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公开(公告)号：US20180192983A1
公开(公告)日：2018-07-12
申请号：US15911749
申请日：2018-03-05
Applicant: LightLab Imaging, Inc.
Inventor： Lorina Dascal , Itai Winkler , Stavit Cohen , Amit Cohen , Desmond C. Adler
IPC: A61B6/00 , G06T7/00 , G06T7/11 , A61B5/00 , A61B8/12 , A61B6/12 , A61B90/00 , A61B5/055 , A61B6/03 , A61B8/00 , A61M25/10
CPC classification number: A61B6/5258 , A61B5/0035 , A61B5/0066 , A61B5/0073 , A61B5/0084 , A61B5/055 , A61B6/032 , A61B6/12 , A61B6/4417 , A61B6/463 , A61B6/481 , A61B6/487 , A61B6/504 , A61B6/507 , A61B6/5247 , A61B8/12 , A61B8/4245 , A61B8/565 , A61B2090/364 , A61B2090/3735 , A61B2090/3966 , A61M25/104 , A61M2025/105 , G06T7/0012 , G06T7/11 , G06T2207/10101 , G06T2207/30101 , G06T2207/30204
Abstract: In part, the invention relates to processing, tracking and registering angiography images and elements in such images relative to images from an intravascular imaging modality such as, for example, optical coherence tomography (OCT). Registration between such imaging modalities is facilitated by tracking of a marker of the intravascular imaging probe performed on the angiography images obtained during a pullback. Further, detecting and tracking vessel centerlines is used to perform a continuous registration between OCT and angiography images in one embodiment.
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公开(公告)号：US20180192957A1
公开(公告)日：2018-07-12
申请号：US15913300
申请日：2018-03-06
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Chenyang Xu
IPC: A61B5/00
CPC classification number: A61B5/6852 , A61B5/0066 , A61B5/7264
Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.
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公开(公告)号：US20180177404A1
公开(公告)日：2018-06-28
申请号：US15736575
申请日：2016-06-23
Applicant: LightLab Imaging, Inc.
Inventor： Yu Liu
CPC classification number: A61B5/0084 , A61B3/102 , A61B5/0066 , G02B3/0087 , G02B6/4206 , G02B6/4212
Abstract: In part, the disclosure relates to a lens assembly. The lens assembly can be used to direct light for sensing and imaging. In one embodiment, the lens assembly is a component of an intravascular data collection probe such as an optical coherence tomography probe. The lens assembly can include an optical fiber having a first diameter and a gradient index lens that includes a rod having a length L. The rod can include a substantial planar end and a polished end. The rod can include a longitudinal axis and a second diameter. The second diameter is greater than the first diameter in one embodiment. The substantially planar end is optically coupled to an endface of the optical fiber. The refractive index changes along the length L of the rod.
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94.发明授权公开(公告)号：US10006753B2
公开(公告)日：2018-06-26
申请号：US14573749
申请日：2014-12-17
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt , Victor Grinberg
CPC classification number: G01B9/02055 , G01B9/02004 , G01B9/02044 , G01B9/02074 , G01B9/02083 , H03G3/3084 , H04B10/616 , H04B10/671
Abstract: In part, aspects of the invention relate to methods, apparatus, and systems for intensity and/or pattern line noise reduction in a data collection system such as an optical coherence tomography system that uses an electromagnetic radiation source and interferometric principles. In one embodiment, the noise is intensity noise or line pattern noise and the source is a laser such as a swept laser. One or more attenuators responsive to one or more control signals can be used in conjunction with an analog or digital feedback network in one embodiment.
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公开(公告)号：US20180003482A1
公开(公告)日：2018-01-04
申请号：US15644668
申请日：2017-07-07
Applicant: LightLab Imaging, Inc.
Inventor： Joseph M. Schmitt
CPC classification number: G01B9/02091 , A61B5/0066 , A61B5/0073 , G01B9/02004 , G01B9/02043 , G01B9/02069 , G01B2290/25 , G01B2290/60 , H01S3/1062 , H01S5/141 , H01S5/146 , H01S5/5036
Abstract: In one embodiment of the invention, a semiconductor optical amplifier (SOA) in a laser ring is chosen to provide low polarization-dependent gain (PDG) and a booster semiconductor optical amplifier, outside of the ring, is chosen to provide high polarization-dependent gain. The use of a semiconductor optical amplifier with low polarization-dependent gain nearly eliminates variations in the polarization state of the light at the output of the laser, but does not eliminate the intra-sweep variations in the polarization state at the output of the laser, which can degrade the performance of the SS-OCT system.
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Patent Agency Ranking
公开(公告)号：US20170301084A1
公开(公告)日：2017-10-19
申请号：US15488005
申请日：2017-04-14
Applicant: LightLab Imaging, Inc.
Inventor： Ajay Gopinath
Abstract: In part, the disclosure relates to an automated method of branch detection with regard to a blood vessel imaged using an intravascular modality such as OCT, IVUS, or other imaging modalities. In one embodiment, a representation of A-lines and frames generated using an intravascular imaging system is used to identify candidate branches of a blood vessel. One or more operators such as filters can be applied to remove false positives associated with other detections.
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公开(公告)号：US20170024910A1
公开(公告)日：2017-01-26
申请号：US15218871
申请日：2016-07-25
Applicant: LightLab Imaging, Inc.
Inventor： Christopher E. Griffin , Sonal Ambwani , Satish Kaveti
CPC classification number: G06T11/003 , A61B5/0066 , A61B5/0084 , A61B5/02007 , A61B5/065 , A61B5/6852 , A61B5/7217 , A61B8/0841 , A61B8/0891 , A61B8/12 , A61B8/5223 , A61M25/09 , G06T7/0012 , G06T7/194 , G06T7/70 , G06T2207/10068 , G06T2207/10101 , G06T2207/30101
Abstract: In part, the disclosure relates to methods of guidewire detection in intravascular data sets such as scan lines, frames, images and combinations thereof. Methods of generating one or more indicia of a guidewire in a representation of blood vessel are also features of the disclosure. A carpet view is generated in one embodiment and regions of relatively higher contrast are detected as candidate guidewire regions. In one embodiment, the disclosure relates to selective removal of guidewire segments from a set of intravascular data and the display of a representation of a blood vessel via a user interface. Representations of a guidewire can be toggled on and off in one embodiment.
Abstract translation: 部分地，本公开涉及血管内数据集（例如扫描线，帧，图像及其组合）中的导丝检测方法。 在血管表示中产生导丝的一个或多个标记的方法也是本公开的特征。 在一个实施例中产生地毯视图，并且检测相对较高对比度的区域作为候选导丝区域。 在一个实施例中，本公开涉及从一组血管内数据中选择性地移除导丝段并经由用户界面显示血管的表示。 在一个实施例中，导丝的表示可以被打开和关闭。
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公开(公告)号：US20160335766A1
公开(公告)日：2016-11-17
申请号：US15157340
申请日：2016-05-17
Applicant: LightLab Imaging, Inc.
Inventor： Sonal Ambwani , Christopher E. Griffin , James G. Peterson , Satish Kaveti , Joel M. Friedman
CPC classification number: A61B34/20 , A61B2034/2065 , G06K9/4647 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T7/174 , G06T2200/24 , G06T2207/10068 , G06T2207/10101 , G06T2207/30021 , G06T2207/30052 , G06T2207/30101
Abstract: The disclosure relates, in part, to computer-based visualization of stent position within a blood vessel. A stent can be visualized using intravascular data and subsequently displayed as stent struts or portions of a stent as a part of a one or more graphic user interface(s) (GUI). In one embodiment, the method includes steps to distinguish stented region(s) from background noise using an amalgamation of angular stent strut information for a given neighborhood of frames. The GUI can include views of a blood vessel generated using distance measurements and demarcating the actual stented region(s), which provides visualization of the stented region. The disclosure also relates to display of intravascular diagnostic information such as indicators. An indicator can be generated and displayed with images generated using an intravascular data collection system. The indicators can include one or more viewable graphical elements suitable for indicating diagnostic information such as stent information.
Abstract translation: 本公开部分地涉及血管内支架位置的基于计算机的可视化。 支架可以使用血管内数据进行可视化，随后显示为支架支架或支架的一部分作为一个或多个图形用户界面（GUI）的一部分。 在一个实施例中，该方法包括使用对于给定的帧邻域的角支架支柱信息的合并来区分支架区域与背景噪声的步骤。 GUI可以包括使用距离测量产生的血管的视图，并且划分实际的支架区域，其提供支架区域的可视化。 本公开还涉及显示血管内诊断信息，如指标。 可以使用血管内数据收集系统生成和显示图像来指示。 指示器可以包括适于指示诸如支架信息的诊断信息的一个或多个可视图形元素。
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公开(公告)号：US20160313507A1
公开(公告)日：2016-10-27
申请号：US15198581
申请日：2016-06-30
Applicant: LightLab Imaging, Inc.
Inventor： Desmond Adler , Stephen McCartin , Christopher Petersen
IPC: G02B6/26 , G02B23/26 , G02B27/09 , G01B9/02 , A61B1/07 , A61B1/00 , A61B1/005 , A61B5/02 , G02B6/32 , A61B5/00
CPC classification number: G02B6/262 , A61B1/00137 , A61B1/005 , A61B1/07 , A61B5/0066 , A61B5/0068 , A61B5/0071 , A61B5/0084 , A61B5/02007 , A61B5/6852 , A61B5/6876 , A61B6/504 , G01B9/02091 , G02B5/08 , G02B6/32 , G02B6/4204 , G02B6/4206 , G02B6/4214 , G02B23/2423 , G02B23/26 , G02B27/005 , G02B27/0911 , G02B27/095 , G02B27/0955 , G02B27/0977 , G02B27/0994
Abstract: In part, the invention relates to optical caps having at least one lensed surface configured to redirect and focus light outside of the cap. The cap is placed over an optical fiber. Optical radiation travels through the fiber and interacts with the optical surface or optical surfaces of the cap, resulting in a beam that is either focused at a distance outside of the cap or substantially collimated. The optical elements such as the elongate caps described herein can be used with various data collection modalities such optical coherence tomography. In part, the invention relates to a lens assembly that includes a micro-lens; a beam director in optical communication with the micro-lens; and a substantially transparent film or cover. The substantially transparent film is capable of bi-directionally transmitting light, and generating a controlled amount of backscatter. The film can surround a portion of the beam director.
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100.发明授权公开(公告)号：US09462950B2
公开(公告)日：2016-10-11
申请号：US13907217
申请日：2013-05-31
Applicant: LightLab Imaging, Inc.
Inventor： Chenyang Xu
CPC classification number: A61B5/0066 , A61B5/0084 , A61B5/6852 , A61B5/7425 , A61B2576/00 , G06K9/46 , G06K9/6267 , G06K2009/4666 , G06T5/00 , G06T7/0012 , G06T7/11 , G06T7/246 , G06T7/73 , G06T7/90 , G06T2207/10101 , G06T2207/20061 , G06T2207/20182 , G06T2207/30101
Abstract: In one embodiment, the invention relates to a processor based method for generating positional and other information relating to a stent in the lumen of a vessel using a computer. The method includes the steps of generating an optical coherence image data set in response to an OCT scan of a sample containing at least one stent; and identifying at least one one-dimensional local cue in the image data set relating to the position of the stent.
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