公开(公告)号：US12129347B2

公开(公告)日：2024-10-29

申请号：US18326244

申请日：2023-05-31

Applicant: CHEM LINK, INC.

Inventor： Baljinder Kaur ,  Jonathan Ballema

IPC: C08J3/24 ,  C08G63/91 ,  C09D201/10 ,  C09J183/00 ,  C09J183/04 ,  C09J183/10 ,  C09J185/00 ,  C09J201/10 ,  C09K3/10 ,  C08G77/12 ,  C08G77/20

CPC classification number: C08J3/24 ,  C08G63/91 ,  C09D201/10 ,  C09J183/00 ,  C09J183/04 ,  C09J183/10 ,  C09J185/00 ,  C09J201/10 ,  C09K3/1018 ,  C08G77/12 ,  C08G77/20 ,  C08J2333/06 ,  C08J2333/12 ,  C08J2347/00 ,  C08J2367/00 ,  C08J2371/00 ,  C08J2381/04 ,  C08J2383/04

Abstract: The invention described herein generally pertains to a composition that includes a silyl-terminated polymer having silyl groups linked to a polymer backbone via triazole. The silyl-terminated polymer is a reaction product of a functionalized polymer backbone and a functionalized silane. The polymer backbone includes a first functional group, which may be one of an azide or an alkyne. The functionalized silane includes a second functional group may also be one of an azide or an alkyne, but is also different from the first functional group. The functionalized polymer backbone is reacted with the functionalized silane in the presence of a metal catalyst.

公开(公告)号：US11970559B2

公开(公告)日：2024-04-30

申请号：US17258314

申请日：2019-07-11

Applicant: BYK-Chemie GmbH

Inventor： Inno Rapthel ,  Frederik Piestert ,  Andre Rapthel ,  Thorsten Kroller ,  Patricia Oostendorp ,  Lisa Bachmann

IPC: C08F283/02 ,  C08F212/08 ,  C08F220/14 ,  C08F220/18 ,  C08F220/32 ,  C08G63/91 ,  C08L51/08 ,  C08L67/04

CPC classification number: C08F283/02 ,  C08F212/08 ,  C08F220/14 ,  C08F220/1804 ,  C08F220/1808 ,  C08F220/325 ,  C08L51/08 ,  C08L67/04 ,  C08G63/91 ,  C08G63/912 ,  C08L2203/16 ,  C08L2203/30 ,  C08L2205/02

Abstract: A grafted polylactic acid is provided, wherein the grafted polylactic acid contains carboxylic acid end groups in an amount from 1.0 to 10.0 mg KOH/g and contains epoxide groups in an amount from 0.005 to 0.500 mmol/g.

公开(公告)号：US20180250410A1

公开(公告)日：2018-09-06

申请号：US15908112

申请日：2018-02-28

Applicant: INSTITUT QUIMIC DE SARRIA CETS FUNDAClÓ PRIVADA

Inventor： Salvador Borros Gomez ,  Victor RAMOS PEREZ ,  Nathaly SEGOVIA RAMOS ,  Pere DOSTA PONS

IPC: A61K47/34 ,  A61K9/51 ,  A61K31/7088 ,  A61K31/7105 ,  C12N15/113 ,  A61K31/713 ,  C08G73/02 ,  C08G63/91 ,  C12N15/88 ,  A61K38/00 ,  C08G69/10

CPC classification number: A61K47/34 ,  A61K9/5146 ,  A61K9/5192 ,  A61K31/7088 ,  A61K31/7105 ,  A61K31/713 ,  A61K38/00 ,  C08G63/91 ,  C08G69/10 ,  C08G73/02 ,  C08G73/028 ,  C12N15/113 ,  C12N15/88 ,  C12N2310/14 ,  C12N2310/141

Abstract: Disclosed are polymers that are poly(beta-amino ester)s (PBAEs) modified with at least one oligopeptide. The polymers may be used in any field where polymers have been found useful including (but not limited to) in medical fields, particularly in drug delivery. The polymers are particularly useful in delivering a polynucleotide such as DNA, RNA, and siRNA, a small molecule, or a protein. Also disclosed are compositions comprising said polymers and an active agent, methods of encapsulating an agent in a matrix of said polymers, and said polymers and compositions for use in medicine.

公开(公告)号：US20180201727A1

公开(公告)日：2018-07-19

申请号：US15743939

申请日：2016-08-16

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yu Yang ,  Jiyoung Park ,  Suresh S. Iyer ,  Christopher W. A. Krohe ,  Kyle P. Starkey ,  Timothy D. Fletcher ,  Dong-Wei Zhu ,  Thomas E. S. Muehle ,  Jeffrey A. Peterson ,  Thomas J. Blong

IPC: C08G63/685 ,  C08G63/692 ,  C08G63/54 ,  C08G63/695 ,  C08G63/91 ,  C08L77/12

CPC classification number: C08G63/6856 ,  B32B7/12 ,  B32B27/08 ,  B32B27/32 ,  B32B27/322 ,  B32B27/36 ,  B32B2250/02 ,  B32B2327/12 ,  B32B2327/18 ,  B32B2367/00 ,  C08G63/12 ,  C08G63/127 ,  C08G63/16 ,  C08G63/18 ,  C08G63/181 ,  C08G63/54 ,  C08G63/685 ,  C08G63/688 ,  C08G63/6884 ,  C08G63/6886 ,  C08G63/692 ,  C08G63/6926 ,  C08G63/695 ,  C08G63/6956 ,  C08G63/91 ,  C08G63/916 ,  C08G63/918 ,  C08G69/44 ,  C08L67/02 ,  C08L67/03 ,  C08L67/06 ,  C08L77/12 ,  C08L2203/16 ,  C09J167/02 ,  C09J167/03 ,  C09J167/06 ,  Y10T428/28 ,  Y10T428/2843 ,  Y10T428/2852 ,  Y10T428/3154 ,  Y10T428/31544 ,  Y10T428/31786 ,  Y10T428/31797

Abstract: Polyester polymers are described comprising polymerized units comprising a hydroxy functional aromatic group wherein the hydroxy group has been functionalized with an adhesion promoting group. In some embodiments, the polyester polymer comprises polymerized units have the general structure (A) wherein L1 and L2 are independently divalent linking groups comprising an ester group; and RA is an adhesion promoting group bonded to the oxygen atom by means of an ionic or covalent bond. In other embodiments, film articles, laminates are described and methods of making functionalized polyester polymers are described.

公开(公告)号：US20180112034A1

公开(公告)日：2018-04-26

申请号：US15394483

申请日：2016-12-29

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Heather D. Maynard

IPC: C08G63/91 ,  C07H3/04 ,  C08G63/78

CPC classification number: C08G63/912 ,  A61K38/00 ,  A61K38/193 ,  A61K47/24 ,  A61K47/34 ,  A61K47/58 ,  A61K47/593 ,  C07H3/04 ,  C08B37/0006 ,  C08F220/40 ,  C08F2220/285 ,  C08F2438/03 ,  C08G63/08 ,  C08G63/6852 ,  C08G63/688 ,  C08G63/6882 ,  C08G63/78 ,  C08G63/91 ,  C08G2230/00 ,  C12P19/12 ,  C08F216/38

Abstract: Structures and methods of making biodegradable trehalose co-polymers are disclosed. Specifically, biodegradable trehalose co-polymers consist of the general structure R5—[R1R2C—CR3R4]n-[DG]m—R6, wherein R1-R4 are independently selected from hydrogen or a side chain comprising at least one carbon atom, and wherein at least one of R1-R4 is a side chain comprising -L-trehalose, wherein L is a linker molecule that links trehalose to the monomer through at least one of the trehalose hydroxyl groups (—OH), wherein DG is a biodegradable group, and wherein R5 and R6 are end groups.

公开(公告)号：US20180064822A1

公开(公告)日：2018-03-08

申请号：US15807335

申请日：2017-11-08

Applicant: Nektar Therapeutics

Inventor： Antoni Kozlowski

IPC: C08G65/48 ,  C08G63/91 ,  A61K31/7088

CPC classification number: A61K47/58 ,  A61K31/7088 ,  A61K47/60 ,  A61K47/6901 ,  C08G63/91 ,  C08G65/48

Abstract: The invention provides for preparing a polymer-active agent conjugate, the method comprising the steps of reacting an amino acid derivative with a biologically active agent under conditions to form a polymer-active agent conjugate.

公开(公告)号：US20180050983A1

公开(公告)日：2018-02-22

申请号：US15556806

申请日：2016-03-10

Applicant: DAIKIN INDUSTRIES, LTD. ,  TOKYO INSTITUTE OF TECHNOLOGY

Inventor： Tadashi KANBARA ,  Tsuyoshi NOGUCHI ,  Toshikazu TAKATA ,  Hiromitsu SOGAWA ,  Shunsuke MONJIYAMA ,  Toyokazu TSUTSUBA

IPC: C07C291/06 ,  C08G63/685 ,  C08G63/91 ,  C08G63/08 ,  C08F120/36

CPC classification number: C07C291/06 ,  C08F120/36 ,  C08G63/08 ,  C08G63/16 ,  C08G63/6856 ,  C08G63/91 ,  C08G63/916 ,  C08K5/32 ,  C08L101/02

Abstract: The present invention provides a compound of the formula (I): wherein, R1 is a hydrogen atom or a hydrocarbon group; R2 is —R4—R5; R3 is —R4—R5 or —R4—R6; R4 is a divalent organic group; R5 is OH, SH, COOH or NHR9; R9 is a hydrogen atom or an alkyl group having 1-6 carbon atoms; and R6 is a hydrogen atom or an alkyl group having 1-6 carbon atoms.

公开(公告)号：US20180039193A1

公开(公告)日：2018-02-08

申请号：US15553306

申请日：2016-02-22

Applicant: Sanyo Chemical Industries, Ltd.

Inventor： Masaru Honda ,  Tsuyoshi Izumi ,  Hiroshi Odajima ,  Masashi Minaki

IPC: G03G9/087 ,  C08K5/29 ,  C08G63/91 ,  C08L67/00

CPC classification number: G03G9/08755 ,  C08G63/00 ,  C08G63/91 ,  C08K5/29 ,  C08L67/00 ,  G03G9/087 ,  G03G9/08786 ,  G03G9/08795 ,  G03G9/08797

Abstract: Provided is a toner binder which attains all of low-temperature fixing properties, gloss, and hot offset resistance and gives a toner that satisfies the flowability, high-temperature storability, charge stability, pulverizability, image strength, flex cracking resistance, and document anti-offset properties. The present invention is a toner binder which comprises a polyester resins and has a surfactant content of 100 ppm or less and in which the THF-insoluble components and the THF-soluble components respectively have a storage modulus (Pa) at 150° C., G′x150, and the storage modulus (Pa) at 150° C., G′y150, which satisfy the following relationships (1) and (2). G′x150≧10,000  (1) G′x150/G′y150≧500  (2)

公开(公告)号：US20170362373A1

公开(公告)日：2017-12-21

申请号：US15532834

申请日：2015-11-30

Applicant: BASF SE

Inventor： Kian MOLAWI ,  Robert LOOS ,  Andreas KUNKEL

IPC: C08G18/42 ,  C08G63/91 ,  C08G18/73

CPC classification number: C08G18/428 ,  C08G18/4286 ,  C08G18/73 ,  C08G63/08 ,  C08G63/18 ,  C08G63/181 ,  C08G63/60 ,  C08G63/78 ,  C08G63/80 ,  C08G63/91 ,  C08G63/916

Abstract: The present invention relates to biodegradable copolyesters with molecular weight Mn from 10 000 to 100 000 measured by GPC, obtainable via reaction of i) from 51 to 84% by weight, based on the copolyester, of a branched polyester middle block produced from aliphatic or aliphatic and aromatic dicarboxylic acids and from aliphatic dihydroxy compounds with molecular weight Mn from 5000 to 25 000 measured by 1H NMR with from 15.9 to 48.9% by weight, based on the copolyester, of a lactide in the presence of a catalyst, and then the resultant polyester triblock with molecular weight Mn measured by 1H NMR from 5800 to 49 500 with ii) from 0.1 to 3% by weight, based on the copolyester, of a diisocyanate. The present invention further relates to a process for the production of, and to the use of, the abovementioned biodegradable copolyesters.

公开(公告)号：US09839695B2

公开(公告)日：2017-12-12

申请号：US15136632

申请日：2016-04-22

Applicant: Nektar Therapeutics

Inventor： Antoni Kozlowski

IPC: A61K47/00 ,  A61K47/48 ,  C08G65/48 ,  A61K31/7088 ,  C08G63/91 ,  A61K47/60 ,  A61K47/69

CPC classification number: A61K47/58 ,  A61K31/7088 ,  A61K47/60 ,  A61K47/6901 ,  C08G63/91 ,  C08G65/48

Abstract: The invention provides for preparing a polymer-active agent conjugate, the method comprising the steps of reacting an amino acid derivative with a biologically active agent under conditions to form a polymer-active agent conjugate.