公开(公告)号：US20150316510A1

公开(公告)日：2015-11-05

申请号：US14748490

申请日：2015-06-24

Applicant: OLYMPUS CORPORATION

Inventor： Ikutoshi FUKUSHIMA ,  Hisashi ODE ,  Tomio ENDO

IPC: G01N29/06 ,  G01N29/24

CPC classification number: G01N29/0681 ,  G01N29/221 ,  G01N29/2418 ,  G01N29/262 ,  G01N2291/02466 ,  G01N2291/101 ,  G01N2291/106 ,  G02B21/002

Abstract: A photoacoustic microscope includes an objective lens that irradiates a specimen with excitation light, a light scanning unit that deflects the excitation light to scan the specimen, an acoustic lens that converts a wavefront of a photoacoustic wave generated by the specimen due to irradiation with the excitation light, a photoacoustic wave detection unit that detects the photoacoustic wave from the acoustic lens, a drive unit that displaces at least one of the acoustic lens and the photoacoustic wave detection unit, and a control unit that controls the drive unit, in synchronization with scanning of the excitation light by the light scanning unit, so that the photoacoustic wave is incident on the photoacoustic wave detection unit perpendicularly.

Abstract translation: 光声显微镜包括用激发光照射样本的物镜，使激发光偏转以扫描样本的光扫描单元，将通过激发照射而由样本产生的光声波的波前转换的声透镜 光，检测来自声透镜的光声波的光声波检测单元，移位声透镜检测单元中的至少一个的驱动单元，以及与扫描同步地控制驱动单元的控制单元 通过光扫描单元产生激发光，使得光声波垂直入射到光声检测单元上。

公开(公告)号：US20220155213A1

公开(公告)日：2022-05-19

申请号：US17591006

申请日：2022-02-02

Applicant: OLYMPUS CORPORATION

Inventor： Takuma DEZAWA ,  Tomio ENDO

IPC: G01N15/14 ,  C12N5/078 ,  G01N21/47

Abstract: An erythrocyte differentiation monitoring apparatus includes a laser light source that radiates a pulsed laser beam in a hemoglobin absorption wavelength range onto a cell within a culture container, a probe that receives a photoacoustic wave emitted from the cell within the culture container as a result of the cell being irradiated with the pulsed laser beam emitted from the laser light source, and a processor that evaluates the progress of differentiation of the cell into an erythrocyte based on the intensity of the photoacoustic wave received by the probe.

公开(公告)号：US20170130188A1

公开(公告)日：2017-05-11

申请号：US15333274

申请日：2016-10-25

Applicant: OLYMPUS CORPORATION

Inventor： Yoshihiro UE ,  Tomio ENDO ,  Osamu ONO ,  Akira MATSUSHITA ,  Yohei TANIKAWA

IPC: C12M1/34 ,  H04N5/232 ,  H04N5/225

CPC classification number: C12M41/46 ,  C12M41/14 ,  C12M41/36 ,  H04N5/2252 ,  H04N5/2253 ,  H04N5/2256 ,  H04N5/23296

Abstract: An observation apparatus is equipped with a housing including a top plate that is a stage on which a container that accommodates a sample is placed; an optical system accommodated in the housing; an imaging device configured to capture an image of the sample with light from the sample that has entered through the stage and the optical system; and a motor that is a power source of a moving mechanism configured to make the optical system move in a direction along the stage. At least one of the imaging device or the motor is placed outside the housing.