公开(公告)号：US11913947B2

公开(公告)日：2024-02-27

申请号：US17355338

申请日：2021-06-23

Applicant: BOE TECHNOLOGY GROUP CO., LTD.

Inventor： Haonan Liu ,  Yudan Yin ,  Ding Ding

IPC: G01N33/68 ,  G01N21/33 ,  G01N21/64 ,  G01N33/52 ,  C07C309/65 ,  C07C309/73 ,  A01N1/02 ,  G01N1/40 ,  G01N33/543 ,  B01L3/00

CPC classification number: G01N33/5438 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2200/12 ,  B01L2300/0819 ,  B01L2300/12 ,  B01L2300/165

Abstract: The present disclosure provides a digital immunochip and a manufacture method thereof. The digital immunochip includes a first substrate and a second substrate which are opposite to each other. The first substrate includes: a first base substrate; at least one driving electrode on the first base substrate and configured to drive an object to be detected to move; a dielectric layer on a side of the at least one driving electrode away from the first base substrate and covering the at least one driving electrode; and a first hydrophobic layer on a side of the dielectric layer away from the first base substrate. The second substrate includes: a second base substrate; and an immunoassay substance on a side of the second base substrate proximal to the first hydrophobic layer of the first substrate and including an antigen or an antibody.

公开(公告)号：US12269030B2

公开(公告)日：2025-04-08

申请号：US17631461

申请日：2021-03-03

Applicant: BOE Technology Group Co., Ltd.

Inventor： Yudan Yin ,  Jing Yu ,  Haonan Liu ,  Zhukai Liu

IPC: B01L3/00 ,  C23C16/40 ,  C23C16/50 ,  C23C16/56

Abstract: Disclosed are a detection chip and a modification method therefor. A surface activation treatment is performed on a hydrophilic layer of the detection chip, such that a hydroxy-containing modification group is formed on a surface of the hydrophilic layer; and a solution containing an oxy compound is then used to perform a surface epoxidation treatment on the hydrophilic layer in order to form an epoxy-containing modification group on the surface of the hydrophilic layer.