A high-speed multiple units train end windshield comprehensive performance test bed of the present invention is mainly composed of a motion end windshield and six-degree-of-freedom motion device assembly, a fixed end windshield and supporting device assembly, a dynamic contour measurement device assembly and a control system. The fixed end windshield and supporting device assembly is composed of a fixed end supporting frame, a fixed end windshield and installing base assembly and a fixed end simulation end wall, the fixed end supporting frame is a doorframe-shaped frame structure formed by welding the square tubes and is installed on a test bed foundation via a fixed end supporting frame ground rail, and the fixed end simulation end wall is installed on the fixed end supporting frame via a three dimensional force sensor and a connecting plate device of the three dimensional force sensor. The high-speed multiple units train end windshield comprehensive performance test bed of the present invention adopts the windshield clamps and the three dimensional force sensor device to measure the stress conditions of the windshields segmentally, can detect the usage performances of the windshields on an actual operation working condition more really and effectively, and can find out the windshield damage reasons rapidly.