The invention discloses a frame positioning and clamping device A of a parameter test board for gantry-type bogies. The frame positioning and clamping device A mainly comprises two thrust crossbeam assemblies (including a first thrust crossbeam assembly c and a second thrust crossbeam assembly k), four transverse positioning mechanism assemblies (including a first transverse positioning mechanism assembly a, a second transverse positioning mechanism assembly b, a third transverse positioning mechanism assembly h and a fourth transverse positioning mechanism assembly j), four longitudinal positioning mechanism assemblies (including a first longitudinal positioning mechanism assembly d, a second longitudinal positioning mechanism assembly e, a third longitudinal positioning mechanism assembly m and a fourth longitudinal positioning mechanism assembly n) and two vertical positioning mechanism assemblies (including a first vertical positioning mechanism assembly f and a second vertical positioning mechanism assembly g). By the frame positioning and clamping device, frames are vertically, transversely and longitudinally positioned and clamped, the frame positioning and clamping device is convenient to operate and reliable in connection, and testing operation of the parameter test board for the bogies is guaranteed.