公开(公告)号：US20250037984A1

公开(公告)日：2025-01-30

申请号：US18709488

申请日：2022-08-26

Applicant: SHIMADZU CORPORATION

Inventor： Ryo FUJITA ,  Tomoyoshi MATSUSHITA

IPC: H01J49/10 ,  H01J49/24 ,  H01J49/42

Abstract: When a gas is supplied from a gas supply unit (19) to a collision cell (11) in detection of a first target ion, before detection of the first target ion, a controller (22) applies a voltage having a first adjustment voltage value to an electrode located on a downstream side of the collision cell (11) in an ion traveling direction, the first adjustment voltage value being obtained by adding an adjustment value to a first detection voltage value corresponding to the first target ion, and in detection of the first target ion, the controller (22) applies a voltage having the first detection voltage value to the electrode located on the downstream side of the collision cell (11) in the ion traveling direction. The adjustment value is a value indicating a polarity opposite to a polarity of the first target ion.

公开(公告)号：US20240426795A1

公开(公告)日：2024-12-26

申请号：US18822365

申请日：2024-09-02

Applicant: Battelle Memorial Institute

Inventor： Timothy E. Lane ,  Chris L. Scott ,  Brian Hopp

IPC: G01N30/72 ,  A01M7/00 ,  G01N30/02 ,  H01J49/04 ,  H01J49/10

Abstract: Systems and methods of the present disclosure include the use of a tracer in agricultural spray solutions, and preferably a metal tracer, to determine if off-target drift of an active ingredient (AI) is based on drift caused during application or volatility of Al after application.

公开(公告)号：US20240426719A1

公开(公告)日：2024-12-26

申请号：US18750686

申请日：2024-06-21

Applicant: ENERGYSOURCE MINERALS, LLC

Inventor： Carlos Maria Valerio

IPC: G01N1/38 ,  G01N1/40 ,  G01N1/44 ,  G01N21/71 ,  H01J49/10

Abstract: The invention generally relates to a method for analyzing magnetic impurities and materials in lithium hydroxide monohydrate. Any magnetic materials (e.g., Cr, Fe, Co, Nd, Ni, Sm, and other rare earth elements) in the lithium hydroxide monohydrate (LHM) are recovered by a neodymium, glass-encased magnetic stir bar and then subjected to acid digestion. The digested LHM samples are analyzed using Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) or Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). The inventive method provides a standardized procedure for analyzing or measuring magnetic impurities in the LHM samples to determine if the LHM end product meets a lithium-ion battery manufacturer's specifications for battery-grade lithium hydroxide monohydrate.

公开(公告)号：US12163919B2

公开(公告)日：2024-12-10

申请号：US17208455

申请日：2021-03-22

Applicant: Bruker Scientific LLC

Inventor： Melvin Andrew Park

IPC: G01N27/622 ,  G01N27/623 ,  H01J49/04 ,  H01J49/06 ,  H01J49/10 ,  H01J49/42

Abstract: The invention provides a trapped ion mobility separator (TIMS) and methods to operate it wherein an ion region of the TIMS, through which ions travel along an axis from an entrance to an exit, has an elongate cross-sectional profile perpendicular to the axis with a long dimension and a short dimension. First and second counteracting forces on the ions along the axis are provided, wherein at least one of the first and second forces has an effect on the ions that is ion mobility dependent, and wherein at least one of the first and second forces varies spatially along the axis such that ions are trapped and separated by ion mobility. Different embodiments provide the first and second forces using different combinations of gas flow and electric field potential, and employ various electrode structures that provide the system with different advantageous characteristics.

公开(公告)号：US20240363324A1

公开(公告)日：2024-10-31

申请号：US18292897

申请日：2022-03-15

Applicant: SHIMADZU CORPORATION

Inventor： Tomoyoshi MATSUSHITA

IPC: H01J49/10 ,  H01J49/04

CPC classification number: H01J49/105 ,  H01J49/0422

Abstract: A mass spectrometer includes: a roughing vacuum pump; a turbomolecular pump; a first chamber from which a gas is discharged by the roughing vacuum pump; a second chamber into which hydrogen gas is introduced, the second chamber being located at a stage subsequent to the first chamber; a third chamber provided with a detector, the third chamber being located at a stage subsequent to the second chamber; a gas-discharge tube that forms a gas-discharge flow from the first chamber to the roughing vacuum pump; and a gas-discharge tube that forms a gas-discharge flow from each of the second chamber and the third chamber to the gas-discharge tube by the turbomolecular pump. The mass spectrometer introduces, into the gas-discharge tube, an additional gas having a molecular weight higher than a molecular weight of the hydrogen gas.

公开(公告)号：US20240353432A1

公开(公告)日：2024-10-24

申请号：US18686846

申请日：2022-08-26

Applicant: Helmholtz Zentrum München - Deutsches Forschungszentrum Für Gesundheit Und Umwelt (GmbH) ,  Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin

Inventor： Bernhard MICHALKE ,  Vivek VENKATARAMANI

IPC: G01N33/90 ,  G01N27/447 ,  H01J49/10

CPC classification number: G01N33/90 ,  G01N27/44721 ,  G01N27/44743 ,  G01N27/44791 ,  H01J49/105 ,  G01N2800/22

Abstract: The present invention relates to an ex vivo analytic method for analysis of a sample (S1), comprising the steps: A) Determining Fe2+, Fe3+, Fe-Ferritin and total Fe content in sample (S1), comprising the steps: A1) Separating simultaneously Fe2+, Fe3+ and Fe-Ferritin present in a sample (S1); and A2) Quantifying simultaneously Fe2+, Fe3+, Fe-Ferritin separated in step A1) and total Fe based on sample (S1); B) Determining S and Se containing compounds content of sample (S1), comprising the steps B1) Separating simultaneously S and Se containing compounds present in sample (S1); and B2) Quantifying simultaneously S and Se containing compounds separated in step B1) of sample (S1). Further, the invention relates to a kit for performing the analytic method.

公开(公告)号：US12112934B2

公开(公告)日：2024-10-08

申请号：US17753036

申请日：2020-08-22

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： Yves Le Blanc

IPC: H01J49/00 ,  H01J49/10

CPC classification number: H01J49/0036 ,  H01J49/0045 ,  H01J49/10

Abstract: Before each sample of a series of batch samples is introduced into a liquid sample delivery device, an ion source device receives aqueous mobile phase solution from the liquid sample delivery device and ionizes its compounds, producing an ion beam. A tandem mass spectrometer performs a neutral loss or precursor ion scan on the ion beam to measure intensities of two or more precursor ions corresponding to a known aqueous mobile phase solution compound. Intensity measurements for each of the two or more different precursor ions are compared to previously stored intensities to determine the threshold times at which these measurements indicate orifice contamination. A threshold time is then predicted for a known compound of interest of the batch samples based on the m/z value of the known compound of interest and the m/z value and the threshold time of each of the two or more different precursor ions.

公开(公告)号：US12104710B2

公开(公告)日：2024-10-01

申请号：US17949538

申请日：2022-09-21

Applicant: Elemental Scientific, Inc.

Inventor： Caleb Gilmore ,  Tyler Yost

IPC: F16K31/06 ,  F16K31/08 ,  H01J49/04 ,  H01J49/10

CPC classification number: F16K31/0617 ,  F16K31/08 ,  H01J49/0495 ,  H01J49/105

Abstract: Valve assemblies are described that provide magnetic coupling between a valve actuator and a valve body housing the valve rotor and stator. A valve assembly embodiment, includes, but is not limited to, a valve body, the valve body including at least one magnet, and a rotor and a stator configured to define a plurality of fluid flow passageways; a valve actuator configured to drive the rotor via a drive shaft; and an actuator mount coupled to the valve actuator and configured to magnetically couple with the at least one magnet of the valve body to magnetically couple the valve body and the valve actuator.

公开(公告)号：US12087568B2

公开(公告)日：2024-09-10

申请号：US18456678

申请日：2023-08-28

Applicant: Standard BioTools Canada Inc.

Inventor： Alexander Loboda ,  Raymond Jong ,  Michael Sullivan ,  Serguei Vorobiev ,  Robert Rotenberg ,  Emil D. Stratulativ ,  Maxim Voronov ,  Mark Armstrong

IPC: H01J49/00 ,  H01J49/04 ,  H01J49/10 ,  H05H1/24 ,  H05H1/30

CPC classification number: H01J49/105 ,  H01J49/0027 ,  H01J49/0463 ,  H05H1/2406 ,  H05H1/30

Abstract: Inductively coupled plasma (ICP) analyzers use an ICP torch to generate a plasma in which a sample is atomized an ionized. Analysis of the atomic ions can be performed by atomic analysis, such as mass spectrometry (MS) or atomic emission spectrometry (AES). Particle based ICP analysis includes analysis of particles such as cells, beads, or laser ablation plumes, by atomizing and ionizing particles in an ICP torch followed by atomic analysis. In mass cytometry, mass tags of particles are analyzed by mass spectrometry, such as by ICP-MS. Systems and methods of the subject application include one or more of: a demountable ICP torch holder assembly, an external ignition device; an ICP load coil comprising an annular fin, particle suspension sample introduction fluidics, and ICP analyzers thereof.

公开(公告)号：US12009196B2

公开(公告)日：2024-06-11

申请号：US17596458

申请日：2019-07-01

Applicant: SHIMADZU CORPORATION

Inventor： Takahiro Harada ,  Yuichi Kuratani

IPC: H01J49/10 ,  H01J49/04

CPC classification number: H01J49/0409 ,  H01J49/10

Abstract: An ionizer 1 detachably attached to a main body 2 of an ion analyzing device includes an ionization section 10 including a sample stage 14 and light irradiation units 11, 12, and 13 configured to irradiate a sample placed on the sample stage 14 with light, a base body, and a movably-holding mechanism which is provided on the base body and configured to hold the ionization section in a manner movable or rotatable about one or more axes.