Regulated method for separating a mixture

    公开(公告)号:US12214297B2

    公开(公告)日:2025-02-04

    申请号:US18509100

    申请日:2023-11-14

    Abstract: The invention relates to a method for separating a mixture in an installation comprising a first system comprising a plurality of chromatography columns, a second system downstream of the first system and a tank fed by an outlet line of the first system and feeding the second system with a continuous stream, the method successively comprising, in a cyclical manner, in a given part of the first system, steps of collecting a raffinate, injecting the mixture to be separated, collecting an extract and injecting a mobile phase; wherein the method further comprises the measurement of the purity and/or yield of at least one collected fraction, comprising: the determination of the concentration of at least two species of the mixture to be separated in the fraction collected in the tank; and the determination of the purity and/or yield of at least one species of the fraction collected in the tank.

    SYSTEMS INCLUDING SIMULATED MOVING BED SEPARATORS FOR HIGH PURITY FRUCTOSE PRODUCTION AND RELATED METHODS

    公开(公告)号:US20210347801A1

    公开(公告)日:2021-11-11

    申请号:US17307609

    申请日:2021-05-04

    Abstract: A method of enriching a material comprising glucose, fructose, and one or more components inert to isomerization using chromatography to produce a high purity fructose product. An embodiment of the method purifies high fructose corn syrup from a feedstock into three product streams: a first fraction rich in glucose, a second fructose product comprising an extract of fructose purity exceeding about 95%, and a third less pure fructose fraction comprising fructose ranging from about 55% to about 90% fructose purity. The third less pure fructose fraction may be combined with 42% fructose syrup to produce saleable mid-purity fructose product, such as having 55% fructose purity. An SMB system is also disclosed and comprises a first SMB separator, a second SMB separator, and an isomerization chamber.

    Regulated Method For Separating A Mixture

    公开(公告)号:US20210023474A1

    公开(公告)日:2021-01-28

    申请号:US16762457

    申请日:2018-11-16

    Abstract: The invention relates to a method for separating a mixture in a system comprising a plurality of chromatography columns, the method successively comprising, in a cyclical manner, in a given part of the system: a step of collecting a raffinate; a step of injecting the mixture to be separated; a step of collecting an extract; and a step of injecting a mobile phase; the method further comprising: determining, in a node of the system, the history of a variable representing the concentration of at least one species contained in the mixture to be separated; detecting, within said history, a characteristic point between the beginning of a step of collecting the extract and the end of the following step of collecting the raffinate; comparing the position of the characteristic point in relation to a target position; and adjusting the carrier volume of the characteristic point, modifying the position of the characteristic point in order to bring the position of the characteristic point closer to the target position; the volume of the mobile phase injected per cycle being maintained higher than, or equal to, a minimum threshold and/or lower than, or equal to, a maximum threshold. The invention also relates to a computer program for carrying out the steps of such a method, to a storage medium on which such a program is recorded, and to a system comprising a processor coupled to a memory on which such a program is recorded.

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