公开(公告)号：US06624132B1

公开(公告)日：2003-09-23

申请号：US09606478

申请日：2000-06-29

Applicant: Victor Fuk-Pong Man ,  Steven Eugene Lentsch ,  Yvonne Marie Killeen

Inventor： Victor Fuk-Pong Man ,  Steven Eugene Lentsch ,  Yvonne Marie Killeen

IPC: C11D742

CPC classification number: C11D3/046 ,  C11D3/38663

Abstract: The present invention relates to a liquid enzyme cleaning composition in which the enzyme is stable at alkaline pH and in the presence of water at concentrations of at least about 50 to about 60 weight percent. In one embodiment, the composition of the invention stabilizes the enzyme with potassium borate.

Abstract translation: 本发明涉及液体酶清洁组合物，其中该酶在碱性pH下和在至少约50至约60重量％浓度的水存在下是稳定的。 在一个实施方案中，本发明的组合物用硼酸钾稳定酶。

公开(公告)号：US06610642B2

公开(公告)日：2003-08-26

申请号：US09922678

申请日：2001-08-06

Applicant: Chanchal Kumar Ghosh ,  André Cesar Baeck ,  Ryohei Ohtani ,  Alfred Busch ,  Michael Stanford Showell ,  Ayrookaran J. Poulose ,  Volker Schellenberger ,  James T. Kellis, Jr. ,  Christian Paech ,  Joanne Nadherny ,  Donald P. Naki ,  Katherine D. Collier ,  Robert M. Caldwell

Inventor： Chanchal Kumar Ghosh ,  André Cesar Baeck ,  Ryohei Ohtani ,  Alfred Busch ,  Michael Stanford Showell ,  Ayrookaran J. Poulose ,  Volker Schellenberger ,  James T. Kellis, Jr. ,  Christian Paech ,  Joanne Nadherny ,  Donald P. Naki ,  Katherine D. Collier ,  Robert M. Caldwell

IPC: C11D742

CPC classification number: C11D3/386

Abstract: The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of Bacillus amyloliquefaciens subtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 of Bacillus amyloliquefaciens subtilisin; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a subtitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of Bacillus amyloliquefaciens subtilisin; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of Bacillus amyloliquefaciens subtilisin; and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.

公开(公告)号：US06602841B1

公开(公告)日：2003-08-05

申请号：US09581717

申请日：2000-06-16

Applicant: Nathaniel T. Becker ,  Robert I. Christensen, Jr. ,  Alfred L. Gaertner ,  Mahmood M. Ghani ,  Douglas A. Dale

Inventor： Nathaniel T. Becker ,  Robert I. Christensen, Jr. ,  Alfred L. Gaertner ,  Mahmood M. Ghani ,  Douglas A. Dale

IPC: C11D742

CPC classification number: C12N9/48 ,  C11D3/38672 ,  C11D11/0088

Abstract: A granule having high stability and low dust is described. The granule includes a hydrated barrier material having moderate or high water activity. Also described are methods of producing the granules.

Abstract translation: 描述了具有高稳定性和低灰尘的颗粒。 颗粒包括具有中等或高水分活性的水合阻隔材料。 还描述了生产颗粒的方法。

公开(公告)号：US06384007B1

公开(公告)日：2002-05-07

申请号：US09709172

申请日：2000-11-09

Applicant: Daniel Convents ,  Monique Doornink ,  Jean Hypolites Koek ,  David William Thornthwaite ,  Nicole Zwets

Inventor： Daniel Convents ,  Monique Doornink ,  Jean Hypolites Koek ,  David William Thornthwaite ,  Nicole Zwets

IPC: C11D742

CPC classification number: C11D3/26 ,  C11D3/38654 ,  C11D3/3942

Abstract: There is provided a process for enhancing the activity of a phenol oxidizing enzyme, comprising adding to the enzyme, as an enhancer for the activity of said enzyme, one or more compounds having the having the formula: wherein Z1 and Z2 are electron withdrawing groups, independently selected from the group consisting of optionally substituted alkyl/(hetero)aryl- -sulfone, -sulfoxide, -sulfonate, -carbonyl, -oxalyl, -amidoxalyl, -hydrazidoxalyl, -carboxyl and esters and salts thereof, -amidyl, -hydrazidyl, nitrile. The process is especially useful for removing colored stains from fabrics in a washing process.

Abstract translation: 提供了一种增强酚氧化酶活性的方法，包括向所述酶中添加作为所述酶活性的增强剂，一种或多种具有下式的化合物：其中Z1和Z2是吸电子基团， - 杂芳基 - - 砜，亚砜， - 磺酸酯， - 羰基， - 草酰基， - 酰氨基草酰基， - 酰基草酰基， - 羧基及其酯和盐， - 氨基， ，腈。 该方法特别适用于在洗涤过程中从织物上除去有色污渍。

公开(公告)号：US06380146B1

公开(公告)日：2002-04-30

申请号：US09596994

申请日：2000-06-20

Applicant: Greta Johanna Breel ,  Daniel Convents ,  Willem Van Liemt ,  Ton Swarthoff ,  Robin Stefan Twisker

Inventor： Greta Johanna Breel ,  Daniel Convents ,  Willem Van Liemt ,  Ton Swarthoff ,  Robin Stefan Twisker

IPC: C11D742

CPC classification number: C11D3/30 ,  C11D3/26 ,  C11D3/349 ,  C11D3/38609 ,  C11D3/3942

Abstract: There is provided a bleaching detergent composition comprising one or more surfactants, a phenol oxidizing enzyme and a compound which acts as enhancer for the phenol oxidizing enzyme, said composition having an Enhancer Index as herein defined of at least 12 and prefereably in the range of 15-50.

Abstract translation: 提供了一种漂白洗涤剂组合物，其包含一种或多种表面活性剂，酚氧化酶和充当酚氧化酶的增强剂的化合物，所述组合物具有如本文所定义的至少12并且优选在15范围内的增强子指数 -50。

公开(公告)号：US06638902B2

公开(公告)日：2003-10-28

申请号：US09773965

申请日：2001-02-01

Applicant: James J. Tarara ,  Sally K. Swart ,  Tareasa Lynn Bradley ,  Reid Rabon ,  Denise Chandler

Inventor： James J. Tarara ,  Sally K. Swart ,  Tareasa Lynn Bradley ,  Reid Rabon ,  Denise Chandler

IPC: C11D742

CPC classification number: C11D3/10 ,  C11D3/386 ,  C11D3/38627 ,  C11D3/38636 ,  C11D3/38645 ,  C11D3/38654 ,  C11D11/0041

Abstract: The present invention relates to a solid enzyme cleaning composition in which the enzyme is stable in the presence of mixtures of carbonate and bicarbonate at alkaline pH, and methods employing this composition. The enzyme cleaning composition preferably employs weight ratios of carbonate and bicarbonate to stabilize one or more enzymes in a solid, a concentrate, and/or a use composition, and at temperatures higher than ambient.

公开(公告)号：US06431370B1

公开(公告)日：2002-08-13

申请号：US09590371

申请日：2000-06-08

Applicant: Edit L. Braunstein ,  Nathaniel T. Becker ,  Thomas P. Graycar

Inventor： Edit L. Braunstein ,  Nathaniel T. Becker ,  Thomas P. Graycar

IPC: C11D742

CPC classification number: C11D3/046 ,  C11D3/386 ,  C11D3/38672 ,  C11D11/0082 ,  C12N9/00 ,  C12N9/54 ,  C12N9/98 ,  C12P1/00 ,  Y10S435/816

Abstract: Detergent formulations are prepared by directly agglomerating a fermentation broth extract, containing a detergent-type enzyme and a nonionic detergent-type surfactant, with a suitable detergent base mixture, without need for prior isolation of the enzyme.

Abstract translation: 通过将含有洗涤剂型酶和非离子洗涤剂型表面活性剂的发酵肉汤提取物与合适的洗涤剂基础混合物直接附聚而制备洗涤剂制剂，而不需要事先分离酶。

公开(公告)号：US06380140B1

公开(公告)日：2002-04-30

申请号：US09171501

申请日：1999-03-22

Applicant: Kathleen Paatz ,  Wilfried Raehse ,  Werner Pichler ,  Horst Upadek

Inventor： Kathleen Paatz ,  Wilfried Raehse ,  Werner Pichler ,  Horst Upadek

IPC: C11D742

CPC classification number: B01J2/20 ,  B01J2/28 ,  C11D3/228 ,  C11D3/38672 ,  C12N9/98

Abstract: Enzyme granules suitable for incorporating into detergents or cleaners are provided containing an enzyme, a carrier material and a granulation auxiliary containing phosphated starch. The phosphated starch preferably has a mean degree of phosphation ranging from 1.5 to 2.5. Carrier materials include starch, cereal flour, cellulose, alkali metal aluminosilicate, layer silicate and alkali metal salts. Enzymes include proteases, lipases, amylases and cellulases. A preferred carrier material contains water-swellable starch, sucrose, cereal flour and cellulose powder. The granulation auxiliary may contain a co-granulation auxiliary selected from polyethylene glycol having an average molecular weight of from 200 to 6,000, 1,2-propylene glycol and a poly-ethoxylate having a specified formula. Preferred granules have a mean particle size of from 0.3 to 3 mm. The granules are produced by forming a mixture containing an aqueous enzyme-containing liquid such as a concentrated fermentation broth, the carrier material and the granulation auxiliary, extruding the mixture, cutting the extruded mixture to obtain granules, and optionally spheronizing and drying the granules.

Abstract translation: 提供适于掺入洗涤剂或清洁剂的酶颗粒，其含有酶，载体材料和含有磷酸化淀粉的造粒助剂。 磷酸化淀粉的平均磷酸化度优选为1.5〜2.5。 载体材料包括淀粉，谷物粉，纤维素，碱金属铝硅酸盐，层状硅酸盐和碱金属盐。 酶包括蛋白酶，脂肪酶，淀粉酶和纤维素酶。 优选的载体材料含有水溶胀性淀粉，蔗糖，谷物粉和纤维素粉末。 造粒助剂可以含有选自平均分子量为200〜6000的聚乙二醇，1,2-丙二醇和具有规定式的聚乙氧基化物的共制粒助剂。 优选的颗粒具有0.3至3mm的平均粒度。 通过形成含有含水液体如浓缩发酵液，载体材料和造粒辅助剂的混合物，挤出混合物，切割挤出的混合物以获得颗粒，并任选地使球形化和干燥颗粒而制备颗粒。

公开(公告)号：US06369011B1

公开(公告)日：2002-04-09

申请号：US09445270

申请日：2000-03-03

Applicant: Saroj Rai ,  Paul Elliott Correa ,  Yong Zhu ,  Thomas Paul Graycar ,  Richard Ray Bott

Inventor： Saroj Rai ,  Paul Elliott Correa ,  Yong Zhu ,  Thomas Paul Graycar ,  Richard Ray Bott

IPC: C11D742

CPC classification number: C11D3/386 ,  C12N9/54

Abstract: The present relates to cleaning compositions comprising a protease enzyme which is a carbonyl variant having an amino acid sequence not found in nature, which is derived by replacement of a plurality of amino acid residues of a precursor carbonyl ydrolase with different amino acids.

Abstract translation: 本发明涉及包含蛋白酶的清洁组合物，其是具有在自然界中未发现的氨基酸序列的羰基变体的蛋白酶，其通过用不同氨基酸置换前体羰基葡糖苷酶的多个氨基酸残基而衍生。