摘要:
A compound and method for detecting hypoxic cells and tissue are provided. The compound includes a probe selected from the group consisting of a hypoxia sensitive 2-nitroimidazole containing fluorescence imaging probe, a hypoxia sensitive reversible ON-OFF fluorescence imaging probe, a hypoxia sensitive azo-based fluorescence imaging probe, and combinations thereof. The method includes contacting the cells or tissue with the probe of any one of claims 1-13 and detecting fluorescent intensity of the cell or tissue, wherein increased fluorescent intensity indicates that the cells or tissue is hypoxic. Also provided are a method of synthesizing the compound and a method for synthesizing a therapeutic agent including the compound.
摘要:
Compounds of the formula ##STR1## in which the variables are as defined in the claims and which are suitable diazo components for the synthesis of fibre-reactive dyes are described.
摘要:
Reactive dyes of formula in which D is a residue of a dyestuff of the perinone or naphthoylene - dibenzimidazole series, X is an -SO2NH- or -SO2NHRNH-SO2- bridge, R is an aliphatic or aromatic residue, Y is a hydrogen atom or a sulpho group and n is a positive integer are prepared by reacting a sulphochloride of a perinone or naphthoylene-benzimidazole compound with an amine of formula in which Y is as above or by reacting the sulphochlorides with aliphatic or aromatic diamines the products of which reaction are then treated with sulphochlorides of formula in which Y is as above. Alternatively the perinone or naphthylene-benzimidazole sulphochlorides are condensed with mono-acetyldiamines followed by deacetylation and treatment with the 2-chloro-benzthiazole-sulphochlorides above. Orange-brown-yellow shades are obtained in cotton materials by conventional dyeing processes.
摘要:
Provided is a fiber reactive dye composition which can dye or print cellulose based fiber materials or materials containing the fiber materials uniformly with good build-up property and reproducibility and give dyed or printed products excellent in various fastness properties.A fiber reactive dye composition which comprises at least five reactive dyes selected from the groups of reactive dyes represented by the following formulas (I) to (VII) respectively in the form of free acid: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, alkyl, ureido or the like, R.sub.5 and R.sub.6 are each hydrogen, sulfo or the like, R.sub.3, R.sub.4, R.sub.7 to R.sub.13 and R.sub.15 to R.sub.18 are each hydrogen, alkyl or the like, R.sub.14 is --O-- or ##STR2## A, B, D, E, G, J and L are each phenylene or the like, X.sub.1 to X.sub.6 are each halogen, Y.sub.1 to Y.sub.7 are each --SO.sub.2 CH.dbd.CH.sub.2 or --SO.sub.2 C.sub.2 H.sub.4 Z, Z being a group capable of being split off by the action of an alkali, m.sub.1 to m.sub.4 are each an integer of 1-3, and n is 0 or 1, provided that the composition contains respectively at least one yellow dye selected from those of the formulas (I) and (II), red dye selected from those of the formulas (III) and (IV) and blue dye selected from those of the formulas (V) to (VII).
摘要:
Particular 1,2,3-triazole- and 1,2,4-triazole-based compounds can be used as fluorescent probes. The compounds can optionally be substituted with one or two fluorine atoms. The compounds are effective as specific endoplasmatic reticulum (ER)-trackers for live cell imaging in a fungal cell, such as a pathogenic yeast. Compositions including the fluorescent probes can be used in methods for tracking the endoplasmic reticulum in a fungal cell.
摘要:
A photoelectric conversion element including a photoconductor layer, wherein the photoconductor layer contains semiconductor fine particles carrying a metal complex dye of Formula (I); a metal complex dye, a dye solution, a dye-adsorbed electrode, a dye-sensitized solar cell, and a method for producing the solar cell: M(LD)(LA)·(CI) Formula (I) wherein M represents a metal ion; LD represents a tridentate ligand of formulas (DL-1) to (DL-4); LA represents a specific tridentate ligand; and CI represents a counter ion: Y1 and Y2 represent an oxygen, sulfur, nitrogen, or phosphorus atom; AD and BD represent a hydrocarbon or hetero ring; L represents a linking group of formulas (L-1) to (L-4); and Ra and Rb represent a substituent, X represents a nitrogen or carbon atom; CD represents hetero ring; T represents —O—, —S—, —NRL2— or —PRL3; RL1 to RL3 represent a hydrogen atom or a substituent; and Alk represents an alkylene group.
摘要:
A photoelectric conversion element including a photoconductor layer, wherein the photoconductor layer contains semiconductor fine particles carrying a metal complex dye of Formula (I); a metal complex dye, a dye solution, a dye-adsorbed electrode, a dye-sensitized solar cell, and a method for producing the solar cell: M(LD)(LA)·(CI) Formula (I) wherein M represents a metal ion; LD represents a tridentate ligand of formulas (DL-1) to (DL-4); LA represents a specific tridentate ligand; and CI represents a counter ion: Y1 and Y2 represent an oxygen, sulfur, nitrogen, or phosphorus atom; AD and BD represent a hydrocarbon or hetero ring; L represents a linking group of formulas (L-1) to (L-4); and Ra and Rb represent a substituent, X represents a nitrogen or carbon atom; CD represents hetero ring; T represents —O—, —S—, —NRL2— or —PRL3; RL1 to RL3 represent a hydrogen atom or a substituent; and Alk represents an alkylene group.
摘要:
A dyestuff of the formula ##STR1## where D is a chromophoric residuen is 1 or 2Z is ##STR2## where R is H, C.sub.1-4 alkyl, C.sub.1-4 alkyl substituted by OH, OSO.sub.3 H, CN or SO.sub.3 H or is phenyleach hal independently represents a chlorine or fluorine atom occupying one of the remaining 2-, 4- and 6-positions of the pyridine nucleusX is F, Cl, CN or NO.sub.2Y is H, F, Cl, CN or NO.sub.2.These dyestuffs reactively dye cellulose at low temperatures and are less prone to "acid bleeding" than some known reactive dyes.