5,5-diphenylpent-4-enoic acids and related compounds
    2.
    发明授权
    5,5-diphenylpent-4-enoic acids and related compounds 失效
    5,5-二羟基-4-丁酸及相关化合物

    公开(公告)号:US3829474A

    公开(公告)日:1974-08-13

    申请号:US28536672

    申请日:1972-08-31

    申请人: BEECHAM GROUP LTD

    发明人: BILLETT E MILLER D

    CPC分类号: C07C57/42 C07C57/60 C07C59/64

    摘要: SUBSTITUTED ALKENOIC ACIDS HAVING TWO PHENYL OR LOWER ALKOXYPHENYL GROUPS AND CERTAIN DERIVATIVES HAVE BEEN FOUND TO HAVE EXTROGENIC, E.G., ANTI-FERTILITY PROPERTIES FOR TREATING MENOPAUSAL DISORDERS OR FOR ESTROGENIC REPLACEMENT. TYPICAL COMPOUNDS ARE 2-CARBOXY-5,5-DIPHENYL-4METHYLPENT--4-ENOIC ACIDS, 2-METHYL-4-ETHYL-5,5-DIPHENYL2-CARBOXYPENT-4-ENOIC ACID AND 2,4-DIMETHYL-5-PHENYL5-(4-METHOXY-PHENYL)PENT-4-ENOIC ACID. THE NEW COMPOUNDS ARE FORMULATED AS TABLETS AND CAPSULES FOR ORAL USE AND AS INJECTABLE WITH STERILE WATER,