Method for synthesising vitamin A

    公开(公告)号:US11365169B2

    公开(公告)日:2022-06-21

    申请号:US17269096

    申请日:2019-08-19

    摘要: A method for preparing a compound of formula (I) in which R1 is selected from H and alkyls, R2 is selected from H, alkyls, OR′ where R′ is selected from alkyls, silyls, CO-alkyl, R3 is selected from the acyl groups of the CO(R″) type, and the CO(OR″), CO(NR″R′″), PO(OR″)(OR′″), PO(OR″)(R′″) groups where R″ and R′″, independently of each other, are selected from H and alkyls, R represents a C(R4)═C(R5)(R6) group where R4, R5 and R6, independently of each other, are selected from H, linear or cyclic alkyls and alkenyls, aryls, alkylaryls, or R4 and R5 together form a saturated or unsaturated, substituted or unsubstituted ring, from a compound of formula (II) or a compound of formula (III) in which, R, R1, R2 and R3 have the above definition.

    Cyclopropyl ring opening by alpha alkylation of an aldehyde with a polycyclic olefin

    公开(公告)号:US11267776B2

    公开(公告)日:2022-03-08

    申请号:US16972081

    申请日:2019-10-14

    申请人: FIRMENICH SA

    发明人: Julie Quintaine

    IPC分类号: C07C45/68 C11B9/00 C07C47/225

    摘要: Described herein is a process including alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step in order to provide a compound of formula in a form of any one of its stereoisomers or a mixture thereof and where n represents 1 to 4 and R2 to R5 represent independently of each other, a hydrogen atom or a C1-6 linear alkyl group or a C3-6 branched alkyl group; and R3 and R4 or R5 or, alternatively, R2 and R3 when taken together form a saturated or unsaturated optionally substituted 5 or 6 membered carbocyclic ring.

    Lily of the valley odorant
    6.
    发明授权

    公开(公告)号:US10472591B2

    公开(公告)日:2019-11-12

    申请号:US16333086

    申请日:2017-12-18

    申请人: FIRMENICH SA

    发明人: Christian Chapuis

    摘要: The present invention concerns a compound of formula (I) in the form of any one of its stereoisomers or as a mixture thereof, and wherein carbon 4 of the cyclohexenyl group has an absolute S configuration and R represents a hydrogen atom or a methyl group and their use in perfumery to impart odor notes of white peach and floral type.