公开(公告)号：US11856861B2

公开(公告)日：2023-12-26

申请号：US16767106

申请日：2018-11-23

申请人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

发明人： Jonathan Chavanne ,  Yoan Civet ,  Yves Perriard

IPC分类号： H10N30/88 ,  A61M60/289 ,  A61M60/161 ,  A61M60/486 ,  A61M60/839 ,  A61M39/22 ,  A61M60/117 ,  H10N30/50 ,  H10N30/857

CPC分类号： H10N30/886 ,  A61M39/22 ,  A61M60/117 ,  A61M60/161 ,  A61M60/289 ,  A61M60/486 ,  A61M60/839 ,  H10N30/50 ,  F16F2228/063 ,  H10N30/857

摘要： A spring (3, 3′) comprising a plurality of elements (30), each element (3) comprising a rigid portion (31) and a flexible beam (32), the extremities (320, 321) of the flexible beam being supported by the rigid portion (31), the flexible beam (32) having a single stable position, so that the flexible beam can be deformed when a pressure is exerted between said extremities in the direction of the rigid portion (31), and returns to said single stable position when the pressure is released, and wherein the rigid portion (31) of at least one element (30) is in contact with the flexible beam (32) of the next element between said extremities (320, 321) of the flexible beam (32), so that the spring has a negative stiffness over an operating range. The arrangement ensures a pure radial compression/expansion of the spring.

公开(公告)号：US20240123202A1

公开(公告)日：2024-04-18

申请号：US18398003

申请日：2023-12-27

申请人： NXT Biomedical, LLC

发明人： Glen Rabito ,  Joseph Passman ,  Robert C. Taft ,  Stanton J. Rowe ,  Robert S. Schwartz ,  Alexander Siegel

IPC分类号： A61M27/00 ,  A61B17/00 ,  A61F2/24 ,  A61F2/82 ,  A61M60/161 ,  A61M60/165 ,  A61M60/216 ,  A61M60/289 ,  A61M60/861

CPC分类号： A61M27/002 ,  A61B17/0057 ,  A61F2/2487 ,  A61F2/82 ,  A61M60/161 ,  A61M60/165 ,  A61M60/216 ,  A61M60/289 ,  A61M60/861 ,  A61B2017/00632 ,  A61M2205/75 ,  A61M2206/20 ,  A61M2210/125

摘要： Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

公开(公告)号：US11904120B2

公开(公告)日：2024-02-20

申请号：US18069025

申请日：2022-12-20

申请人： NXT Biomedical, LLC

发明人： Glen Rabito ,  Joseph Passman ,  Robert C. Taft ,  Stanton J. Rowe ,  Robert S. Schwartz ,  Alexander Siegel

IPC分类号： A61M27/00 ,  A61M60/165 ,  A61M60/216 ,  A61B17/00 ,  A61F2/24 ,  A61F2/82 ,  A61M60/161 ,  A61M60/289 ,  A61M60/861

CPC分类号： A61M27/002 ,  A61B17/0057 ,  A61F2/2487 ,  A61F2/82 ,  A61M60/161 ,  A61M60/165 ,  A61M60/216 ,  A61M60/289 ,  A61M60/861 ,  A61B2017/00632 ,  A61M2205/75 ,  A61M2206/20 ,  A61M2210/125

摘要： Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

公开(公告)号：US20230129101A1

公开(公告)日：2023-04-27

申请号：US18069025

申请日：2022-12-20

申请人： NXT Biomedical, LLC

发明人： Glen Rabito ,  Joseph Passman ,  Robert C. Taft ,  Stanton J. Rowe ,  Robert S. Schwartz ,  Alexander Siegel

IPC分类号： A61M27/00 ,  A61M60/165 ,  A61M60/216 ,  A61B17/00 ,  A61F2/24 ,  A61F2/82 ,  A61M60/161 ,  A61M60/289 ,  A61M60/861

摘要： Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

公开(公告)号：US12023479B2

公开(公告)日：2024-07-02

申请号：US17058969

申请日：2019-06-12

申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

发明人： Zain I. Khalpey ,  Zachary David Frankman ,  Marvin J. Slepian

IPC分类号： A61M60/279 ,  A61M60/161 ,  A61M60/17 ,  A61M60/289 ,  A61M60/295 ,  A61M60/468 ,  A61M60/497 ,  A61M60/508 ,  A61M60/837 ,  A61M60/843

CPC分类号： A61M60/279 ,  A61M60/161 ,  A61M60/17 ,  A61M60/289 ,  A61M60/295 ,  A61M60/468 ,  A61M60/497 ,  A61M60/508 ,  A61M60/837 ,  A61M60/843 ,  A61M2205/0216

摘要： A tubular pulsatile ventricular assist device (PVAD) system for providing forward flow of blood in a pulsatile, peristaltic, and non-hemolytic manner to help reduce the amount of blood clotting associated with current ventricular devices on the market. The system can encircle a portion of a blood vessel, and the system can sequentially apply a pressure through each port in a particular pre-determined patter so as to selectively occlude the lumen, thereby creating a pulsatile, peristaltic movement along a length of system. Said movement causes blood to flow through the portion of the blood vessel.

公开(公告)号：US20210361929A1

公开(公告)日：2021-11-25

申请号：US16767106

申请日：2018-11-23

申请人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

发明人： Jonathan CHAVANNE ,  Yoan CIVET ,  Yves PERRIARD

IPC分类号： A61M60/486 ,  H01L41/053 ,  A61M60/161 ,  A61M60/289

摘要： A spring (3, 3′) comprising a plurality of elements (30), each element (3) comprising a rigid portion (31) and a flexible beam (32), the extremities (320, 321) of the flexible beam being supported by the rigid portion (31), the flexible beam (32) having a single stable position, so that the flexible beam can be deformed when a pressure is exerted between said extremities in the direction of the rigid portion (31), and returns to said single stable position when the pressure is released, and wherein the rigid portion (31) of at least one element (30) is in contact with the flexible beam (32) of the next element between said extremities (320, 321) of the flexible beam (32), so that the spring has a negative stiffness over an operating range. The arrangement ensures a pure radial compression/expansion of the spring.

公开(公告)号：US20210205598A1

公开(公告)日：2021-07-08

申请号：US17143068

申请日：2021-01-06

申请人： California Institute of Technology

发明人： Niema M. Pahlevan ,  Morteza Gharib ,  Marie Csete

IPC分类号： A61M60/161 ,  A61M60/289 ,  A61L27/36 ,  A61L27/52 ,  A61M60/465

摘要： A system configured to be at least partially implanted along an aorta includes an inelastic, static member and a pinching member. The pinching member is configured to receive an activation signal at an activation rate and in response to the activation signal, repeatedly compress the aorta at the second location at the activation rate to pump fluid within the aorta in a desired pumping direction. The system is configured to selectively control wave reflections in order to achieve both improved wave dynamics to reduce cardiac load and increased (or at least non-diminished) blood flow to targeted organs within the cardiovascular system.

公开(公告)号：US12005246B2

公开(公告)日：2024-06-11

申请号：US17143068

申请日：2021-01-06

申请人： California Institute of Technology

发明人： Niema M. Pahlevan ,  Morteza Gharib ,  Marie Csete

IPC分类号： A61M60/161 ,  A61L27/36 ,  A61L27/52 ,  A61M60/289 ,  A61M60/465

CPC分类号： A61M60/161 ,  A61L27/3625 ,  A61L27/52 ,  A61M60/289 ,  A61M60/465

摘要： A system configured to be at least partially implanted along an aorta includes an inelastic, static member and a pinching member. The pinching member is configured to receive an activation signal at an activation rate and in response to the activation signal, repeatedly compress the aorta at the second location at the activation rate to pump fluid within the aorta in a desired pumping direction. The system is configured to selectively control wave reflections in order to achieve both improved wave dynamics to reduce cardiac load and increased (or at least non-diminished) blood flow to targeted organs within the cardiovascular system.

公开(公告)号：US11559672B2

公开(公告)日：2023-01-24

申请号：US17662413

申请日：2022-05-06

申请人： NXT Biomedical, LLC

发明人： Glen Rabito ,  Joseph Passman ,  Robert C. Taft ,  Stanton J. Rowe ,  Robert S. Schwartz ,  Alexander Siegel

IPC分类号： A61M27/00 ,  A61M60/165 ,  A61M60/216 ,  A61B17/00 ,  A61F2/24 ,  A61F2/82 ,  A61M60/161 ,  A61M60/289 ,  A61M60/861

摘要： Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

公开(公告)号：US20210205601A1

公开(公告)日：2021-07-08

申请号：US17058969

申请日：2019-06-12

申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

发明人： Zain I. Khalpey ,  Zachary David Frankman ,  Marvin J. Slepian

IPC分类号： A61M60/279 ,  A61M60/17 ,  A61M60/837 ,  A61M60/843 ,  A61M60/161 ,  A61M60/508 ,  A61M60/295 ,  A61M60/497

摘要： A tubular pulsatile ventricular assist device (PVAD) system for providing forward flow of blood in a pulsatile, peristaltic, and non-hemolytic manner to help reduce the amount of blood clotting associated with current ventricular devices on the market. The system can encircle a portion of a blood vessel, and the system can sequentially apply a pressure through each port in a particular pre-determined patter so as to selectively occlude the lumen, thereby creating a pulsatile, peristaltic movement along a length of system. Said movement causes blood to flow through the portion of the blood vessel.