公开(公告)号：US07033614B2

公开(公告)日：2006-04-25

申请号：US10648828

申请日：2003-08-27

Applicant: Phil Linz ,  Rantan K. Chaudhuri

Inventor： Phil Linz ,  Rantan K. Chaudhuri

IPC: A61K7/021 ,  A61K7/08 ,  A61K7/48 ,  A61K7/50 ,  A61K33/00

CPC classification number: A61Q5/12 ,  A61K8/20 ,  A61K33/245 ,  A61K2800/436 ,  A61Q5/02 ,  A61Q19/10 ,  Y10S514/827 ,  Y10S514/828 ,  Y10S514/844 ,  Y10S514/846 ,  Y10S514/848 ,  Y10S514/937 ,  Y10S514/951

Abstract: A rinse-off composition comprising in percent by weight 0.10–10.00 of a dispersion of bismuth oxychloride 3.50–90.00 of a surfactant, 0.001–0.050 of a dye, 3.00–15.00 of an emollient and 10.00–80.00 of water; said dispersion of bismuth oxychloride containing bismuth oxychloride platelet particles having a lateral width of 5–25 microns and a thickness of 20–200 nm, said platelet particles being substantially covered a liquid vehicle and said liquid vehicle being present in an amount sufficient to maintain a stable dispersion and to provide for facile resuspension.

Abstract translation: 一种洗涤组合物，其包含以重量计0.10-10.00的表面活性剂的三氯氧化物3.50-90.00的分散体，0.001-0.050的染料，3.00-15.00的润肤剂和10.00-80.00的水; 所述含有氯氧化铋血小板颗粒的分散体的横向宽度为5-25微米，厚度为20-200nm，所述血小板颗粒基本上覆盖液体载体，所述液体载体的存在量足以维持 稳定的分散和提供轻松的再悬浮。

公开(公告)号：US20050261134A1

公开(公告)日：2005-11-24

申请号：US10967758

申请日：2004-10-18

Applicant: Hugo Demeyere ,  Gunnel Johnasson ,  Mangus Nydén

Inventor： Hugo Demeyere ,  Gunnel Johnasson ,  Mangus Nydén

IPC: A01N25/04 ,  A01N25/16 ,  A61K8/14 ,  A61K8/41 ,  A61K9/127 ,  A61Q5/12 ,  C11D1/62 ,  C11D3/00 ,  C11D3/50 ,  C11D11/00 ,  A61K7/075 ,  A61K7/08

CPC classification number: A61Q13/00 ,  A61K8/14 ,  A61K8/416 ,  A61Q5/12 ,  C07C211/62 ,  C11D1/62 ,  C11D3/0015 ,  C11D3/30 ,  C11D3/502 ,  C11D11/0094

Abstract: Compositions for effectively delivering a water-soluble active material to a surface comprise: (a) from about 1% to about 30%, by weight of the composition, of a dialkyl quaternary ammonium compound having the formula: wherein R1 and R2 are independently C12 to C20 saturated alkyl chains; Y is wherein R4 is ethyl or isopropyl; R3 and R5 are independently methyl, ethyl, hydroxyethyl, or hydroxypropyl; m is 1, 2, or 3; n is 1 or 2; p is 0 or 1; and X− is a suitable anion; (b) from about 0.01% to about 10%, by weight of the composition, of water-soluble active material having a C log P of less than about 2.0; and (c) at least about 60%, by weight of the composition, of water; wherein the compositions contain vesicles having a vesicle permeability index of less than about 1.3. Processes to make the compositions comprise the steps of dispersing the dialkyl quaternary ammonium compound and the water-soluble active material in an aqueous solution to form vesicles having a vesicle permeability index of less than about 1.3.

Abstract translation: 用于有效地将水溶性活性物质递送到表面的组合物包含：（a）按组合物重量计约1％至约30％的具有下式的二烷基季铵化合物：其中R 1， R 2和R 2独立地是C 12〜C 20饱和烷基链; Y是其中R 4是乙基或异丙基; R 3和R 5独立地是甲基，乙基，羟乙基或羟丙基; m为1,2或3; n为1或2; p为0或1; 和X - 是合适的阴离子; （b）占组合物重量的约0.01％至约10％的具有小于约2.0的C log P的水溶性活性材料; 和（c）按组合物重量计至少约60％的水; 其中所述组合物含有囊泡渗透指数小于约1.3的囊泡。 制备组合物的方法包括将二烷基季铵化合物和水溶性活性物质分散在水溶液中以形成囊泡渗透指数小于约1.3的步骤。

公开(公告)号：US20050244360A1

公开(公告)日：2005-11-03

申请号：US11176350

申请日：2005-07-08

Applicant: Nelly Billoni

Inventor： Nelly Billoni

IPC: A61K8/362 ,  A61Q19/00 ,  A61K7/075 ,  A61K7/06 ,  A61K7/08

CPC classification number: A61Q19/008 ,  A61K8/362

Abstract: The invention concerns a cosmetic composition for treating or preventing disorders associated with a greasy skin, in particular by an activity reducing sebum secretion, comprising as active principle at least one dicarboxylic fatty acid or one derivative of such a fatty acid. The invention concerns in particular cosmetic compositions for topical administration. The invention also concerns a cosmetic method for treating or preventing disorders associated with hyperseborrhea.

Abstract translation: 本发明涉及用于治疗或预防与油腻皮肤相关的病症，特别是减少皮脂分泌的活性的化妆品组合物，其包含作为至少一种二羧酸脂肪酸或这种脂肪酸的一种衍生物的活性成分。 本发明特别涉及用于局部给药的化妆品组合物。 本发明还涉及用于治疗或预防与过度脂肪相关的疾病的美容方法。

公开(公告)号：US20050232891A1

公开(公告)日：2005-10-20

申请号：US10825703

申请日：2004-04-16

Applicant: Stephen Moloney ,  Albert Jecminek

Inventor： Stephen Moloney ,  Albert Jecminek

IPC: A61K8/00 ,  A61K8/55 ,  A61K8/58 ,  A61K31/663 ,  A61K31/665 ,  A61K45/00 ,  A61P17/00 ,  A61P17/16 ,  A61Q19/00 ,  A61Q19/08 ,  A61K7/075 ,  A61K7/08

CPC classification number: A61K8/55 ,  A61K31/663 ,  A61K31/665 ,  A61Q19/00 ,  A61Q19/08

Abstract: The present invention provides for the administration of aryl-substituted 1,1-diphosphonate compounds to increase the dermal collagen content of skin and effect improvement in photoaged skin, chronologically aged skin and in skin of postmenopusal women and patients suffering from osteoporosis.

Abstract translation: 本发明提供了芳基取代的1,1-二膦酸盐化合物的施用，以增加皮肤的真皮胶原含量，并且对受影响的妇女和患有骨质疏松症的患者的光老化皮肤，按时间顺序老化的皮肤和皮肤进行改善。

公开(公告)号：US20050214238A1

公开(公告)日：2005-09-29

申请号：US11082801

申请日：2005-03-18

Applicant: Kazuhisa Fukuhara ,  Kenichi Ueyama

Inventor： Kazuhisa Fukuhara ,  Kenichi Ueyama

IPC: A61K8/00 ,  A61K8/04 ,  A61K8/34 ,  A61K8/35 ,  A61K8/36 ,  A61K8/362 ,  A61K8/365 ,  A61K8/39 ,  A61K8/49 ,  A61K8/86 ,  A61K8/89 ,  A61K8/891 ,  A61Q5/00 ,  A61Q5/06 ,  A61Q5/12 ,  C08L83/04 ,  A61K7/06 ,  A61K7/075 ,  A61K7/08 ,  A61K7/11

CPC classification number: A61Q5/12 ,  A61K8/046 ,  A61K8/34 ,  A61K8/362 ,  A61K8/365 ,  A61K8/39 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06

Abstract: Provided is a leave-on hair cosmetic composition, which contains the following components (A) and (B): (A) a citric acid or salt thereof; and (B) at least one or more of an organic solvent selected from the group consisting of aromatic alcohols, N-alkylpyrrolidones, alkylene carbonates, polypropylene glycols, lactones and cyclic ketones, wherein the organic solvent has a ClogP of from −2 to 3; and wherein the leave-on hair cosmetic composition has a pH of from 2 to 5 at 25° C. when diluted to 20 times the weight with water and has a buffering capacity of 0.001 gram equivalent/L or greater but less than 0.2 gram equivalent/L. Provided also is a hair quality improving method which comprises treating the hair with the hair cosmetic composition. The hair cosmetic composition of the present invention can provide benefits such as luster, manageability and good feel of the hair to hair which is apt to be dry and moistureless owing to damage by coloring, permanent weaving, or repetition of excessive blow drying.

Abstract translation: 本发明提供了含有以下组分（A）和（B）的（a）柠檬酸或其盐的脱毛发化妆品组合物。 和（B）至少一种或多种选自芳族醇，N-烷基吡咯烷酮，碳酸亚烷基酯，聚丙二醇，内酯和环酮的有机溶剂，其中有机溶剂的ClogP为-2至3 ; 并且其中所述假毛发化妆品组合物在25℃下的pH为2至5，当用水稀释至20倍时，并且具有0.001克当量/ L或更大但小于0.2克当量的缓冲能力 / L。 还提供了一种头发质量改进方法，其包括用毛发化妆品组合物处理头发。 本发明的毛发化妆品组合物可以提供由于着色，永久编织或重复过度吹干造成的头发易受干燥和无湿感的头发的光泽，易控性和良好的感觉。

公开(公告)号：US20050208012A1

公开(公告)日：2005-09-22

申请号：US11135459

申请日：2005-05-24

Applicant: Martin Albrecht ,  Miklos Ghyczy

Inventor： Martin Albrecht ,  Miklos Ghyczy

IPC: A61K8/00 ,  A61K8/02 ,  A61K8/06 ,  A61K8/14 ,  A61K8/30 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/40 ,  A61K8/42 ,  A61K8/44 ,  A61K8/49 ,  A61K8/55 ,  A61K8/58 ,  A61K8/60 ,  A61K8/63 ,  A61K8/68 ,  A61K8/72 ,  A61K8/73 ,  A61K8/96 ,  A61K8/97 ,  A61K31/7076 ,  A61Q5/02 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/08 ,  A61K7/075 ,  A61K7/08

CPC classification number: A61Q19/08 ,  A61K8/14 ,  A61K8/42 ,  A61K8/44 ,  A61K8/553 ,  A61K8/606 ,  A61Q17/00 ,  A61Q19/00

Abstract: A composition, especially for treatment of aged and/or stressed skin, the composition containing, in addition to water, at least one substance that forms lamellar structures with water. The composition further contains S-adenosylmethionine and/or at least one compound that contains a functional group of the general formula —CH2—N⊕—(CH3)3. The lamellar structure has a layer structure in which an upper layer of the substance is aligned with a lower layer, the hydrophilic groups of the substance each point outwards, and the lipophilic groups of the substance are aligned inwards with one another. The lamellar structure is surrounded by a hydrophilic medium, preferably water.

Abstract translation: 一种组合物，特别是用于治疗老化和/或应激皮肤的组合物，所述组合物除了水之外还含有至少一种与水形成层状结构的物质。 组合物还含有S-腺苷甲硫氨酸和/或至少一种含有通式-CH 2 - （CH 3）官能团的化合物 3 。 层状结构具有层结构，其中物质的上层与下层对准，物质的亲水基团各自指向外部，物质的亲油基团彼此对准。 层状结构被亲水介质，优选水包围。

公开(公告)号：US20050201966A1

公开(公告)日：2005-09-15

申请号：US11061525

申请日：2005-02-22

Applicant: Kenichi Ueyama ,  Nozomi Nagashima ,  Kazuhisa Fukuhara

Inventor： Kenichi Ueyama ,  Nozomi Nagashima ,  Kazuhisa Fukuhara

IPC: A61K8/00 ,  A61K8/34 ,  A61K8/35 ,  A61K8/36 ,  A61K8/362 ,  A61K8/365 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K8/86 ,  A61K8/89 ,  A61K8/891 ,  A61K8/92 ,  A61Q5/00 ,  A61Q5/06 ,  A61Q5/12 ,  A61K7/06 ,  A61K7/075 ,  A61K7/08 ,  A61K7/11

CPC classification number: A61K8/362 ,  A61K8/365 ,  A61K8/44 ,  A61Q5/06 ,  A61Q5/12

Abstract: Provided is a leave-on hair cosmetic composition, which contains the following components (A), (B) and (C): (A) an organic C2-8 dicarboxylic acid or salt thereof, (B) at least one or more of an organic solvent selected from the group consisting of aromatic alcohols, N-alkylpyrrolidones, alkylene carbonates, polypropylene glycols, lactones and cyclic ketones, wherein the organic solvent has a ClogP of from −2 to 3, and (C) an edetic acid or a salt thereof, wherein the cosmetic composition has a pH of from 2 to 5 at 25° C. when diluted to 20 times the weight with water. The present invention also relates to a hair quality improving method which includes treating the hair with the hair cosmetic composition. The hair cosmetic composition of the present invention can provide benefits such as luster, manageability, pliability and elasticity to the hair which is apt to be dry, having lost water therefrom owing to damage by coloring, permanent waving, or repetitive excessive blow drying.

Abstract translation: 本发明提供了含有以下组分（A），（B）和（C）的（A）有机C 2-8二羧酸或其盐的（a） B）至少一种或多种选自芳族醇，N-烷基吡咯烷酮，碳酸亚烷基酯，聚丙二醇，内酯和环酮的有机溶剂，其中有机溶剂的ClogP为-2至3，以及 （C）乙酸或其盐，其中化妆品组合物在25℃下的pH为2至5，当用水稀释至20倍时。 本发明还涉及一种毛发质量改善方法，其包括用毛发化妆品组合物处理头发。 本发明的毛发化妆品组合物可以提供易于干燥的头发的光泽，易控性，柔韧性和弹性，由于着色，永久挥发或重复的过度吹塑干燥而损失水分。

公开(公告)号：US20050180940A1

公开(公告)日：2005-08-18

申请号：US10876953

申请日：2004-06-25

Applicant: Jeffrey Puma

Inventor： Jeffrey Puma

IPC: A61K8/34 ,  A61K8/44 ,  A61K8/46 ,  A61Q7/00 ,  A61K7/06 ,  A61K7/075 ,  A61K7/08

CPC classification number: A61K8/44 ,  A61K8/345 ,  A61K8/466 ,  A61Q7/00

Abstract: A topical composition to protect against hair loss comprising of Sodium diisopropyl naphthalene sulfonate, Butylene glycol, Hampshire N-acyl LED3A, Hamposyl M-30, Hamposyl TC Glutamate. In a preferred embodiment, the composition contains the primary active ingredient sodium diisopropyl naphthalene sulfonate or alkyl naphthalene sulfonate and is commercially available from Cytec Industries under the product name of Aerosol OS Surfactant. The Aerosol OS Surfactant is in the chemical family of alkyl aryl sulfonate. In application as a scalp shampoo for follicle treatment the Aerosol OS Surfactant is an active ingredient of sulfur compounds with anti-inflammatory effects to protect against hair loss. The Aerosol OS can be comprised with any surfactant, chelate or inert carrier, etc. In particular, the composition unblocks the follicle, releases entrapped hair and oxidizes proteins into metabolism allowing the dermal papilla the movement to rise and decline during follicle assimilation.

Abstract translation: 用于防止脱发的局部组合物，其包含二异丙基萘磺酸钠，丁二醇，汉普郡N-酰基LED3A，Hamposyl M-30，Hamposyl TC谷氨酸钠。 在优选的实施方案中，组合物含有主要活性成分萘磺酸二异丙酯钠或萘磺酸烷基酯，并且可从Cytec Industries以商品名Aerosol OS Surfactant商购获得。 气溶胶OS表面活性剂是烷基芳基磺酸盐的化学家族。 作为毛囊处理的头皮洗发剂，Aerosol OS表面活性剂是具有抗炎作用的硫化合物的有效成分，可防止脱发。 气溶胶OS可以与任何表面活性剂，螯合物或惰性载体等组成。特别地，组合物阻断滤泡，释放截留的毛发并将蛋白氧化成代谢，使真皮乳头在卵泡同化期间运动升高和降低。

公开(公告)号：US20050169877A1

公开(公告)日：2005-08-04

申请号：US11040002

申请日：2005-01-24

Applicant: Jean Grollier ,  Claude Dubief ,  Roland De La Mettrie

Inventor： Jean Grollier ,  Claude Dubief ,  Roland De La Mettrie

IPC: A61K8/02 ,  A61Q5/00 ,  B01D11/02 ,  A61K7/06 ,  A61K7/075 ,  A61K7/08

CPC classification number: A61K8/02 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q19/00 ,  A61Q19/10 ,  B01D11/0288

Abstract: The present invention relates to a process for preparing a composition useful, for example, for the treatment of keratin materials, in particular the skin and human keratin fibres such as the hair, to the composition prepared, and also to a process for treating keratin materials using this composition.

Abstract translation: 本发明涉及一种用于制备组合物的方法，所述组合物可用于例如治疗角蛋白材料，特别是皮肤和人角蛋白纤维如毛发，所制备的组合物，以及用于治疗角蛋白材料的方法 使用这个组合。

公开(公告)号：US20050147576A1

公开(公告)日：2005-07-07

申请号：US11028229

申请日：2005-01-04

Applicant: Thierry Cotton

Inventor： Thierry Cotton

IPC: A61K8/00 ,  A61K8/06 ,  A61K8/30 ,  A61K8/33 ,  A61K8/36 ,  A61K8/365 ,  A61K8/49 ,  A61K8/72 ,  A61K8/73 ,  A61K8/89 ,  A61K8/891 ,  A61K8/895 ,  A61K8/92 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  C08L83/04 ,  C08L83/07 ,  A61K7/075 ,  A61K7/08

CPC classification number: A61K8/895 ,  A61K8/49 ,  A61K8/494 ,  A61Q19/007 ,  A61Q19/02 ,  A61Q19/08

Abstract: The present invention relates to a composition including, in a physiologically acceptable medium, at least one organopolysiloxane elastomer and at least one aminosulphonic compound of formula: which is preferably 4-(2-hydroxyethyl)piperazine-1-ethanesulphonic acid (HEPES). It also relates to a cosmetic method for caring for the skin, intended in particular to tone down visible or tactile irregularities in the surface of the skin, in particular to tone down wrinkles and fine lines and/or skin blemishes, and/or to smooth the skin and/or to unify the complexion, comprising the topical application to the skin of the abovementioned composition.

Abstract translation: 本发明涉及一种组合物，其在生理学上可接受的介质中包含至少一种有机聚硅氧烷弹性体和至少一种下式的氨基磺酸化合物：其优选为4-（2-羟基乙基）哌嗪-1-乙磺酸（HEPES）。 它还涉及一种护理皮肤的美容方法，特别是旨在调低皮肤表面的可见或触觉不规则性，特别是调低皱纹和细纹和/或皮肤瑕疵，和/或平滑 皮肤和/或将肤色统一起来，包括局部应用于上述组合物的皮肤。