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    Suppository insertion device, suppository, and method of manufacturing a suppository
    3.
    发明授权
    Suppository insertion device, suppository, and method of manufacturing a suppository 有权

    公开(公告)号：US10149967B2

    公开(公告)日：2018-12-11

    申请号：US14436359

    申请日：2013-10-18

    Applicant: Cristcot LLC

    Inventor： Jennifer J. Davagian ,  Mark C. Ensign

    IPC: A61M31/00 ,  A61J3/08 ,  A61B50/30 ,  A45D40/16 ,  A61K9/02 ,  A61K9/00 ,  A45D40/00 ,  A45D40/08 ,  A45D40/12 ,  A45D40/20

    Abstract: Today's suppositories are typically packaged individually for digital administration into the anal canal of a patient. A suppository applicator described herein, which works with individually packaged suppositories, can alternatively be shipped in a prepackaged operational arrangement with a suppository to enable the patient to administer the suppository through use of the applicator in a single operation after opening a hygienic wrapper containing the applicator-suppository combination. A method for manufacturing a suppository includes manufacturing the suppository in the presence of and in contact with an element configured to be used to insert the suppository into a body cavity. The method may include using the element to define a shape of the suppository during the manufacturing. The resulting applicator-suppository combination is more hygienic and easier to handle than the separate applicator and suppository and provides more efficiency from time of opening the packaging to time of commencing administration of the suppository.

    Holder and packaging for a hardened medicated matrix
    7.
    发明授权
    Holder and packaging for a hardened medicated matrix 失效
    用于硬化药物基质的支架和包装

    公开(公告)号：US5296234A

    公开(公告)日：1994-03-22

    申请号：US776543

    申请日：1991-10-11

    Applicant: Michelle A. Hadaway ,  David E. Kramer ,  Robert J. Best

    Inventor： Michelle A. Hadaway ,  David E. Kramer ,  Robert J. Best

    IPC: A61J1/00 ,  A23G3/00 ,  A23G3/56 ,  A61J3/08 ,  A61J7/00 ,  A61K9/00 ,  A61M35/00 ,  A61K9/14

    CPC classification number: A23G3/563 ,  A61J7/003 ,  A61K9/0056 ,  A61J2205/30

    Abstract: A stick-like holder and packaging, including an overcap and a sealed, light, moisture and tamper resistant foil pouch, for a hardened, medicated matrix affixed to one end of the holder including detent means for releaseably mounting the overcap on the matrix end of the holder and with the holder having a flat, label receiving handle at its other end and a flange to prevent swallowing of the holder when placed in a patient's mouth to medicate or pre-medicate the patient.

    Abstract translation: 一种棒状保持器和包装，包括顶盖和密封的轻，防潮和防篡改箔袋，用于固定在保持器的一端的硬化的药物基质，包括用于将顶盖可释放地安装在基体端的 保持器和保持器在其另一端具有平坦的标签接收手柄和法兰，以防止当放置在患者口中时保持器的吞咽以对患者进行药物治疗或预处理。

    Seamless suppository dispenser
    8.
    发明授权
    Seamless suppository dispenser 失效
    无缝栓剂

    公开(公告)号：US4537311A

    公开(公告)日：1985-08-27

    申请号：US507965

    申请日：1983-06-27

    Applicant: William R. Wilkinson ,  Russell G. Sharp

    Inventor： William R. Wilkinson ,  Russell G. Sharp

    IPC: A61J3/08 ,  B65D83/04

    CPC classification number: A61J3/08

    Abstract: A combination mold and carrier for seamless suppositories. The dispenser has an elongated rectangular one-piece body of a flexible material that is dimensionally stable at ordinary temperatures. A plurality of suppository cavities of uniform constant tapers with rounded bottoms are formed in tubular members extending from the top side of the body. The body side surfaces are tapered with circular cross sections concentrically with the cavities. These side surfaces merge together adjacent the topside and separate into the individual tubular members towards the bottoms of the cavities. The cavities have rounded bottoms to facilitate ejection of suppositories by a manual pinching action. A circular flat base formed on the rounded walls support the body upright on a work surface with the cavities upright to receive a suppository mixture. A rectangular cover with open ends can be slideably mounted over the body in a telescoped relationship. In addition, the body can have identical cavities or cavities varying in axial dimension so that identical and graduated doses can be provided in the suppositories from the same medicinal casting compound.

    Abstract translation: 用于无缝栓剂的组合模具和载体。 分配器具有在普通温度下尺寸稳定的柔性材料的细长矩形单件本体。 具有圆形底部的均匀恒定锥度的多个栓腔形成在从主体的顶侧延伸的管状构件中。 身体侧表面与圆形截面呈圆锥形，与空腔同心。 这些侧面在顶部附近合并在一起，并分离成各个管状构件朝向空腔的底部。 空腔具有圆形底部以便于通过手动夹紧动作排出栓剂。 形成在圆形壁上的圆形扁平底座在工作表面上直立支撑身体，其中腔直立以接收栓剂混合物。 具有开口端的矩形盖可以可伸缩的关系可滑动地安装在身体上。 此外，主体可以具有在轴向尺寸上变化的相同的空腔或空腔，使得可以在来自相同药物浇铸化合物的栓剂中提供相同和分级的剂量。

    Process for forming a barrier phase
    9.
    发明授权
    Process for forming a barrier phase 失效
    形成阻挡相的方法

    公开(公告)号：US4393643A

    公开(公告)日：1983-07-19

    申请号：US402870

    申请日：1982-07-29

    Applicant: Durward Fryar ,  Jerome J. Schmitz

    Inventor： Durward Fryar ,  Jerome J. Schmitz

    IPC: A45D40/16 ,  A61J3/08 ,  B65B7/28 ,  B29D3/00

    CPC classification number: A61Q15/00 ,  A61K8/02 ,  A61K8/0229 ,  A61K8/0237 ,  A61K8/042

    Abstract: A process for forming a barrier phase between two incompatible phases comprising forming a thin layer of barrier material on the outer surface of a pin; placing the coated pin into a package or mold form designed to contain the total product; putting the molten outer phase into the space between the coated pin and the outer wall(s) of the package or mold form and allowing the outer phase to solidify; removing the pin leaving the barrier phase attached to the outer phase; and putting the inner phase into the space previously occupied by the pin.

    Abstract translation: 一种用于在两个不相容相之间形成阻挡相的方法，包括在引脚的外表面上形成阻挡材料薄层; 将涂覆的销放入设计成容纳总产品的包装或模具形式中; 将熔融的外相放入涂覆的销和包装或模具的外壁之间的空间中，并允许外相固化; 去除留下与外相相邻的阻挡相的引脚; 并将内相放入先前由引脚占据的空间中。

    Suppository
    10.
    发明授权
    Suppository 失效
    支持者

    公开(公告)号：US3840010A

    公开(公告)日：1974-10-08

    申请号：US29217972

    申请日：1972-09-25

    Applicant: GIGLIO F

    Inventor： GIGLIO F

    IPC: A61J3/08 ,  A61F15/00

    CPC classification number: A61J3/08

    Abstract: A suppository includes a shaft, a bulbous head secured to one end of the shaft and a conical tail secured to the other end. The head comprises an outwardly curved retention surface and a gradually inwardly curved insertion surface. The tail includes an outwardly tapered retaining surface and a flat base, and has a maximum diameter that is greater than the maximum diameter of the head. A pressure relieving passageway extends through the suppository from one end to the other.

    Abstract translation: 栓剂包括轴，固定到轴的一端的球形头和固定到另一端的锥形尾。 头部包括向外弯曲的保持表面和逐渐向内弯曲的插入表面。 尾部包括向外锥形的保持表面和平坦的基部，并且具有大于头部的最大直径的最大直径。 止血通道从一端延伸通过栓剂。

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