公开(公告)号：US20150275235A1

公开(公告)日：2015-10-01

申请号：US14434116

申请日：2013-10-15

申请人： DSM IP ASSETS B.V.

发明人： Maria Bernedina Elizabeth Jonkers ,  Paul Klaassen ,  Aloysius Wilhelmus Rudolphus Hubertus Teunissen ,  Rene Marcel De Jong

IPC分类号： C12P7/06 ,  C12N9/90 ,  C12N9/12 ,  C12N9/10 ,  C12N9/88 ,  C12N9/92

CPC分类号： C12P7/06 ,  C12N1/16 ,  C12N1/22 ,  C12N9/1022 ,  C12N9/1205 ,  C12N9/88 ,  C12N9/90 ,  C12N9/92 ,  C12P7/10 ,  C12Y202/01001 ,  C12Y202/01002 ,  C12Y207/01017 ,  C12Y404/01005 ,  C12Y501/03001 ,  C12Y503/01006 ,  Y02E50/16 ,  Y02E50/17

摘要： The invention relates to a cell capable of converting one or more pentose sugar and one or more hexose sugar into fermentation product constitutively expressing one or more heterologous or homologous polypeptide having the amino acid sequence set out in SEQ ID NO: 20, or a variant polypeptide thereof having at least 45% identity to SEQ ID NO 20. In an embodiment the heterologous polypeptide has glyoxalase activity.

摘要翻译： 本发明涉及一种能够将一种或多种戊糖和一种或多种己糖转化成组成型表达一种或多种具有SEQ ID NO：20所示氨基酸序列的异源或同源多肽的发酵产物的细胞，或变体多肽 其与SEQ ID NO 20具有至少45％的同一性。在一个实施方案中，异源多肽具有乙二醛酶活性。

公开(公告)号：US20170191087A1

公开(公告)日：2017-07-06

申请号：US15314450

申请日：2015-05-26

申请人： VIB VZW ,  KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R&D

发明人： Johan Thevelein ,  Maria Remedios Foulquié Moreno ,  Meijnen Jean-Paul

IPC分类号： C12P7/06 ,  C12P7/10 ,  C12N9/88

CPC分类号： C12P7/06 ,  C12N9/88 ,  C12P7/10 ,  C12Y404/01005 ,  Y02E50/16 ,  Y02E50/17

摘要： The present invention relates to the use of GLO1 to modulate acetic acid tolerance in yeast. More specifically, it relates to the use of a specific GLO1 allele to confer tolerance to acetic acid, and to improve the fermentation performance of yeast in the presence of acetic acid.

公开(公告)号：US20180282706A1

公开(公告)日：2018-10-04

申请号：US15758885

申请日：2015-09-10

申请人： METABOLIC EXPLORER

发明人： Gwénaëlle CORRE ,  Pascale ALIPRANDI

IPC分类号： C12N9/04 ,  C12P7/18 ,  C12R1/19

CPC分类号： C12N9/0006 ,  C12P7/18 ,  C12R1/19 ,  C12Y101/01 ,  C12Y101/01077 ,  C12Y101/01283 ,  C12Y208/03017 ,  C12Y402/03003 ,  C12Y404/01005 ,  C12Y501/02001

摘要： The present invention relates to new lactaldehyde reductase (LAR) enzymes useful for the production of 1,2-propane-diol and to microorganisms overexpressing said enzymes. The invention also relates to a method for producing 1,2-propanediol by converting lactaldehyde into 1,2-propanediol with said enzymes.

公开(公告)号：US20150359862A1

公开(公告)日：2015-12-17

申请号：US14763360

申请日：2014-01-30

申请人： BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

发明人： Keshore R. Bidasee

IPC分类号： A61K38/51

CPC分类号： A61K38/51 ,  A61K48/00 ,  C12N9/88 ,  C12Y404/01005

摘要： Compositions and methods for inhibiting diabetes-related complications are provided.

摘要翻译： 提供了抑制糖尿病相关并发症的组合物和方法。