公开(公告)号：US12109429B2

公开(公告)日：2024-10-08

申请号：US17117858

申请日：2020-12-10

申请人： KNOW Bio, LLC

发明人： Nathan Stasko ,  David T. Emerson ,  Adam Cockrell ,  F. Neal Hunter ,  Michael John Bergmann ,  Rebecca McDonald ,  Nicholas William Medendorp, Jr. ,  Gerald H. Negley ,  Katelyn P. Reighard

IPC分类号： A61N5/06 ,  H01L27/15

CPC分类号： A61N5/0613 ,  A61N5/0601 ,  A61N5/0603 ,  A61N5/0624 ,  H01L27/15 ,  A61N2005/0611 ,  A61N2005/0626 ,  A61N2005/0647 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/0661 ,  A61N2005/0662 ,  A61N2005/0663

摘要： Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.

公开(公告)号：US20240269476A1

公开(公告)日：2024-08-15

申请号：US18284289

申请日：2022-10-11

申请人： DARAM Inc.

发明人： Seok Hee KANG ,  Hyangmi PARK

IPC分类号： A61N5/06

CPC分类号： A61N5/06 ,  A61N2005/0645 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/0666

摘要： A wearable device for male genitalia in the inventive concept includes a body being in form of a half ring and being in contact with a penis and a scrotum, a hinge connected with the body to be adjustable in an angle to position the penis and the scrotum at an inner side of the body, and a light radiation device provided in the body to radiate light having a predetermined wavelength band in the direction of the penis and the scrotum.

公开(公告)号：US20240066313A1

公开(公告)日：2024-02-29

申请号：US18361338

申请日：2023-07-28

申请人： InnoLux Corporation

发明人： Jih-Ping LIN ,  Chun-Kai LEE ,  Fang-Iy WU ,  Cheng-Hsu CHOU

IPC分类号： A61N5/06

CPC分类号： A61N5/06 ,  A61N2005/0653 ,  A61N2005/066 ,  A61N2005/0663 ,  A61N2005/0664

摘要： An electronic device includes a light emitting layer, a light conversion layer and an adjustable structure. The light emitting layer has a plurality of light emitting units for emitting light. The light conversion layer converts the wavelength of the light emitted by at least one light emitting unit to provide converted light. The adjustable structure is controlled to adjust a light penetrating area to correspond to the affected part to be treated, wherein at least one of the light and the converted light passes through the light penetrating area to irradiate the affected part.

公开(公告)号：US11850444B2

公开(公告)日：2023-12-26

申请号：US16893247

申请日：2020-06-04

申请人： Polyphotonix Limited

发明人： Richard Anthony Kirk ,  Martin Neil Holland ,  Thomas Snell ,  Duncan Hill ,  Luke Stuart Barclay

IPC分类号： A61N5/06 ,  A61F9/02 ,  A61F9/04

CPC分类号： A61N5/0613 ,  A61F9/029 ,  A61F9/04 ,  A61N5/0618 ,  A61N2005/0626 ,  A61N2005/0648 ,  A61N2005/0653 ,  A61N2005/0662

摘要： A medical apparatus and method of operating a medical apparatus are disclosed. The apparatus includes a radiation source for emitting radiation towards an area to be treated of a patient; a mount element arranged to be worn by the patient for positioning the radiation source in a predetermined position relative to the area to be treated; a sensor element arranged to provide a signal indicative of whether the apparatus is being worn by the patient; and at least one controller arranged to receive the signal from the sensor, and to determine whether the apparatus is being worn by the patient, and to determine duration data indicative of the duration for which the radiation source emits radiation whilst the apparatus is being worn by the patient.

公开(公告)号：US20190240500A1

公开(公告)日：2019-08-08

申请号：US16388724

申请日：2019-04-18

申请人： Circuit Therapeutics, Inc.

发明人： David C. Lundmark ,  Karl Deisseroth ,  Fred Moll ,  Dan Andersen ,  Alexander K. Arrow

IPC分类号： A61N5/06 ,  A61M5/20 ,  A61N1/05 ,  A61B17/34 ,  A61B17/00 ,  A61N1/36 ,  A61K38/16 ,  A61K48/00 ,  A61K41/00 ,  A61K38/17 ,  A61M37/00 ,  A61M25/01 ,  A61M5/142

CPC分类号： A61N5/0601 ,  A61B17/00234 ,  A61B17/3403 ,  A61B2017/3413 ,  A61K38/16 ,  A61K38/164 ,  A61K38/168 ,  A61K38/177 ,  A61K41/00 ,  A61K41/0057 ,  A61K48/00 ,  A61K48/0075 ,  A61M5/142 ,  A61M5/20 ,  A61M25/0105 ,  A61M25/0147 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0061 ,  A61M2205/3576 ,  A61M2205/50 ,  A61N1/0551 ,  A61N1/3605 ,  A61N1/36053 ,  A61N5/062 ,  A61N5/0622 ,  A61N2005/0612 ,  A61N2005/0626 ,  A61N2005/0627 ,  A61N2005/063 ,  A61N2005/0631 ,  A61N2005/0643 ,  A61N2005/0651 ,  A61N2005/0653 ,  A61N2005/0665 ,  A61N2005/067

摘要： Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitve proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.

公开(公告)号：US20190070432A1

公开(公告)日：2019-03-07

申请号：US16181899

申请日：2018-11-06

申请人： ROGERS SCIENCES, INC.

发明人： Samuel L. Hill ,  Gary S. Rogers ,  Patrick J. McMullan

IPC分类号： A61N5/06 ,  A61M1/00 ,  A61F13/02 ,  A61N5/067

CPC分类号： A61N5/0624 ,  A61F13/00051 ,  A61F13/0206 ,  A61M1/0088 ,  A61M2205/052 ,  A61M2205/053 ,  A61N5/0616 ,  A61N5/062 ,  A61N2005/063 ,  A61N2005/0645 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/0659 ,  A61N2005/0661 ,  A61N2005/0662 ,  A61N2005/0663 ,  A61N2005/0665 ,  A61N2005/067

摘要： One aspect of the present disclosure is directed to a device for providing light to the surface of a subject, comprising an array of a plurality of light emitting modules, wherein the plurality comprises four light emitting modules, each module of the plurality is flexibly connected to another module of the plurality, and two of the modules of the plurality comprise a polygonal perimeter having 4, 5, or 6 major sides, a light source, and a longest apex-to-apex dimension for a module of 5-50 millimeters, and, optionally, a non-adherent member configured to be adjacent to the subject.

公开(公告)号：US20180304095A1

公开(公告)日：2018-10-25

申请号：US15957551

申请日：2018-04-19

申请人： The Charles Stark Draper Laboratory, Inc.

发明人： Joseph J. Register ,  Carlos A. Segura ,  Gregg E. Favalora

IPC分类号： A61N5/06

CPC分类号： A61N5/0622 ,  A61N5/0601 ,  A61N2005/0612 ,  A61N2005/0653 ,  A61N2005/0667 ,  A61N2005/067

摘要： An optical neurostimulation and detection system and method are disclosed. The system includes a medical device including an implantable body, and a stimulation controller that connects to the medical lead device and provides a light source. One or more light emitter modules of the lead body couple light signals of the light source into modulated light signals, and the modulated light signals are emitted through the one or more light emitter modules to stimulate neural cells and/or neural tissue of a subject. In a preferred embodiment, the light emitter modules include a surface acoustic wave (SAW) transducer that couples the light source into the modulated light signals. Such a system provides emitted light incident upon the neural tissue of a much higher resolution than current systems and methods and can provide long-term implantation with fewer side effects and less tissue damage than current systems and methods.

公开(公告)号：US20180243580A1

公开(公告)日：2018-08-30

申请号：US15753010

申请日：2016-07-21

申请人： LEDskin B.V.

发明人： Josephus Johannes Theodoor Louis Verhoeks ,  Rick Wielens ,  Henri Chrétien Marie Sprengers

IPC分类号： A61N5/06 ,  G16H50/20 ,  G16H40/63

CPC分类号： A61N5/06 ,  A61N5/0621 ,  A61N2005/0632 ,  A61N2005/0645 ,  A61N2005/0651 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/0662 ,  A61N2005/0663 ,  G16H40/63 ,  G16H50/20

摘要： Light therapy systems for example for the ambulant treatment of hyperbilirubinemia. An intelligent wearable light module for ambulatory light therapy disposed in a wearable light module housing arranged to be worn on the body of a patient for illuminating, during use of the module, the skin of the patient with light of a wavelength corresponding to the light therapy.

公开(公告)号：US20180206955A1

公开(公告)日：2018-07-26

申请号：US15880284

申请日：2018-01-25

申请人： DENTSPLY SIRONA Inc.

发明人： Naim Karazivan ,  Paul Pierson ,  Christos Angeletakis

IPC分类号： A61C13/15 ,  A61C7/02 ,  A61C19/06 ,  A61C9/00

CPC分类号： A61C9/0006 ,  A61C1/088 ,  A61C7/023 ,  A61C7/146 ,  A61C9/0013 ,  A61C13/0027 ,  A61C19/003 ,  A61C19/004 ,  A61C19/06 ,  A61C19/063 ,  A61C19/066 ,  A61C2204/002 ,  A61N5/0603 ,  A61N5/0613 ,  A61N2005/0653

摘要： A light curing dental system comprising a light emitting tray that precisely distributes an optimal amount of curing light energy to internal, external and extra oral portions of the dental arch to cure a dental material. The light curing dental system generally includes a light source, a light emitting dental tray, an activation module and a photocurable dental material.

公开(公告)号：US09984584B2

公开(公告)日：2018-05-29

申请号：US14844765

申请日：2015-09-03

申请人： Lotus Magnus, LLC

发明人： Timothy Walter ,  Uma Marar

IPC分类号： A61B5/00 ,  G09B5/02 ,  A61M21/02 ,  A61B5/0478 ,  A61B5/0484 ,  A61B5/0488 ,  A61B5/0496 ,  A61N2/00 ,  G09B19/00 ,  A61B18/00 ,  A61M21/00 ,  A61N5/06

CPC分类号： G09B5/02 ,  A61B3/113 ,  A61B5/01 ,  A61B5/02405 ,  A61B5/02438 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/04842 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/0816 ,  A61B5/11 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/4812 ,  A61B2018/00571 ,  A61M21/00 ,  A61M21/02 ,  A61M2021/0016 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0044 ,  A61M2205/502 ,  A61M2230/10 ,  A61M2230/18 ,  A61M2230/60 ,  A61N2/006 ,  A61N2005/0653 ,  G09B5/06 ,  G09B19/00

摘要： Systems and methods for brain stimulation.