Variable amplitude signals for neurological therapy, and associated systems and methods

    公开(公告)号:US11944817B2

    公开(公告)日:2024-04-02

    申请号:US17900681

    申请日:2022-08-31

    申请人: Nevro Corp.

    发明人: Chris Dawson

    IPC分类号: A61N1/36 A61N1/05

    摘要: Variable amplitude signals for neurological therapy, and associated systems and methods are disclosed. A representative method includes activating automatic delivery of an electrical therapy signal to a patient's spinal cord region at a frequency in a frequency range between 1.5 kHz and 100 kHz, via at least one signal delivery contact carried by an implanted signal delivery device. The delivery can include repeatedly and automatically delivering the electrical therapy signal at each of multiple therapy signal amplitudes to the at least one signal delivery contact, without the therapy signal generating paresthesia in the patient. The foregoing process can be used as a screening tool to screen responders from non-responders in the context of a non-paresthesia-generating therapy, and/or can be used during long-term treatment, for example, for chronic pain.

    POWER CONTROL CIRCUIT FOR STERILIZED DEVICES, AND ASSOCIATED SYSTEMS AND METHODS

    公开(公告)号:US20240017063A1

    公开(公告)日:2024-01-18

    申请号:US18106297

    申请日:2023-02-06

    申请人: Nevro Corp.

    发明人: Bret Foreman

    IPC分类号: A61N1/36 G05F1/56

    CPC分类号: A61N1/36034 G05F1/56

    摘要: A power control circuit for use with devices that will be placed in a flammable sterilizing gas includes a bi-stable switch that is configured to produce an output to place the circuitry of a connected device in a run state or a sleep state. The bi-stable switch controls one or more transistors to drain energy from energy storage devices in the circuitry of the connected device to a level below an ignition level of a sterilizing gas. A remotely actuatable switch can be actuated from outside of a packaging in which the power control circuit is placed to cause the bi-stable switch to produce an output that puts the circuitry in the run state without removing the power control circuit from the packaging.

    TREATMENT OF CONGESTIVE HEART FAILURE WITH ELECTRICAL STIMULATION, AND ASSOCIATED SYSTEMS AND METHODS

    公开(公告)号:US20230271016A1

    公开(公告)日:2023-08-31

    申请号:US18103652

    申请日:2023-01-31

    申请人: Nevro Corp.

    IPC分类号: A61N1/362 A61N1/36

    摘要: Systems and methods for treating congestive heart failure with high frequency stimulation are disclosed. A representative method for treating a patient includes applying an electrical signal having a frequency of from about 1 kHz to about 100 kHz to the patient via a treatment system that includes a signal delivery element in electrical communication with the patient's vagus nerve at a portion of the vagus nerve located at or proximate to the anterior interventricular junction of the patient's heart. The method can further include automatically detecting at least one physiological parameter of the patient, automatically determining at least one of an ejection fraction of the patient's heart and a correlate of the ejection fraction based on the detected parameter, and automatically adjusting the applied signal based on the determined ejection fraction.

    VARIABLE AMPLITUDE SIGNALS FOR NEUROLOGICAL THERAPY, AND ASSOCIATED SYSTEMS AND METHODS

    公开(公告)号:US20230248974A1

    公开(公告)日:2023-08-10

    申请号:US17900681

    申请日:2022-08-31

    申请人: Nevro Corp.

    发明人: Chris Dawson

    IPC分类号: A61N1/36 A61N1/05

    摘要: Variable amplitude signals for neurological therapy, and associated systems and methods are disclosed. A representative method includes activating automatic delivery of an electrical therapy signal to a patient's spinal cord region at a frequency in a frequency range between 1.5 kHz and 100 kHz, via at least one signal delivery contact carried by an implanted signal delivery device. The delivery can include repeatedly and automatically delivering the electrical therapy signal at each of multiple therapy signal amplitudes to the at least one signal delivery contact, without the therapy signal generating paresthesia in the patient. The foregoing process can be used as a screening tool to screen responders from non-responders in the context of a non-paresthesia-generating therapy, and/or can be used during long-term treatment, for example, for chronic pain.

    Leads having sidewall openings, and associated systems and methods

    公开(公告)号:US11420045B2

    公开(公告)日:2022-08-23

    申请号:US16367873

    申请日:2019-03-28

    申请人: Nevro Corp.

    摘要: The present technology is generally directed to spinal cord modulation leads having one or more sidewall openings configured for inserting stylets to steer and/or position the leads within a patient and/or with respect to a pulse generator, and associated systems and methods. In some embodiments, sidewall opening is generally positioned in an intermediate portion of the lead and is operatively coupled to a lumen extending distally to a distal end of the lead, and/or proximally to a proximal end of the lead.