Polyethylene Glycol Aerogels for Targeted Delivery of Pharmaceutical Drubs
    1.
    发明申请
    Polyethylene Glycol Aerogels for Targeted Delivery of Pharmaceutical Drubs 审中-公开
    聚乙二醇气凝胶用于药物Drub的靶向递送

    公开(公告)号:US20110086100A1

    公开(公告)日:2011-04-14

    申请号:US12902184

    申请日:2010-10-12

    Applicant: Yosry A. Attia

    Inventor: Yosry A. Attia

    Abstract: A polyethylene glycol (PEG) aerogel particles having an average particle diameter not substantially above about 2μ, a volumetric porosity of greater than about 50%, and pore sizes capable of retaining drug molecules. A method for preparing such polyethylene glycol (PEG) aerogel particles includes initiating a catalyzed reaction using a catalyst of PEG forming ingredients to form PEG particles; partially drying the formed PEG particles under conditions to control pore size; and subjecting the partially dried formed PEG particles to CO2 supercritical extraction for form the PEG aerogel particles. Drug molecules include chemotherapeutic agents. The surface of the PEG aerogel particles are reactable with a variety of agents, for example, to selectively target tumors, protects irreversible damage to labile proteins, and protects degradation of sensitive drugs with subsequent loss of biological efficacy.

    Abstract translation: 具有基本上不超过约2μ的平均粒径,大于约50%的体积孔隙率和能够保留药物分子的孔径的聚乙二醇(PEG)气凝胶颗粒。 制备这种聚乙二醇(PEG)气凝胶颗粒的方法包括用形成PEG颗粒的PEG形成成分的催化剂引发催化反应; 在控制孔径的条件下部分干燥形成的PEG颗粒; 并将部分干燥的形成的PEG颗粒进行CO 2超临界萃取以形成PEG气凝胶颗粒。 药物分子包括化学治疗剂。 PEG气凝胶颗粒的表面可与各种试剂反应,例如选择性靶向肿瘤,保护不稳定蛋白质的不可逆损伤,并保护敏感药物的降解,随后丧失生物功效。

    Polyethylene Aerogel and Method of Production
    3.
    发明申请
    Polyethylene Aerogel and Method of Production 审中-公开
    聚乙烯气凝胶及其生产方法

    公开(公告)号:US20150247016A1

    公开(公告)日:2015-09-03

    申请号:US14700387

    申请日:2015-04-30

    Applicant: Yosry A. Attia

    Inventor: Yosry A. Attia

    Abstract: A method for making polyethylene aerogels, including high molecular weight aerogels, commences by in a hydrocarbon solvent (e.g., toluene or benzene) in which polyethylene is insoluble at room temperature, adding polyethylene to the solvent heated to a temperature at which said polyethylene is soluble to form a reaction mixture. A free-radical catalyst is added to the reaction mixture and the reaction mixture is held until the desired gelation of the polyethylene has been achieved. The reaction mixture is cooled to about room temperature; and the hydrocarbon solvent is replaced with a gas (e.g., CO2 or air) to form the polyethylene aerogel. Optionally, the cooled reaction mixture can be contacted with an anti-solvent for polyethylene to replace the hydrocarbon solvent with the anti-solvent. Silica aerogel particles can be encapsulated in polyethylene aerogel by adding the particles to the polyethylene gelation reaction mixture.

    Abstract translation: 制造聚乙烯气凝胶的方法,包括高分子量气凝胶,在烃溶剂(如甲苯或苯)中开始,其中聚乙烯在室温下不溶解,加入聚乙烯加热到所述聚乙烯可溶的温度 以形成反应混合物。 向反应混合物中加入自由基催化剂,并保持反应混合物,直至达到所需的聚乙烯凝胶化。 将反应混合物冷却至约室温; 并且用气体(例如CO 2或空气)代替烃溶剂以形成聚乙烯气凝胶。 任选地,冷却的反应混合物可与用于聚乙烯的反溶剂接触以用抗溶剂代替烃溶剂。 通过将颗粒加入到聚乙烯凝胶化反应混合物中,可以将二氧化硅气凝胶颗粒包封在聚乙烯气凝胶中。

    Scrubbing of contaminants from contaminated air streams with aerogel
materials with optional photocatalytic destruction
    4.
    发明授权
    Scrubbing of contaminants from contaminated air streams with aerogel materials with optional photocatalytic destruction 失效
    用气凝胶材料从污染的空气流中清除污染物,任选的光催化破坏

    公开(公告)号:US6080281A

    公开(公告)日:2000-06-27

    申请号:US569709

    申请日:1995-12-08

    Applicant: Yosry A. Attia

    Inventor: Yosry A. Attia

    Abstract: Disclosed is a method for separating a vaporous or gaseous contaminant from an air stream contaminated therewith. This method includes the steps of: (a) passing said contaminated air into a contact zone in which is disposed an aerogel material capable of selecting adsorbing said contaminant from air and therein contacting said contaminated air with an aerogel material; and (b) withdrawing from said zone, air depleted of said contaminant. For present purposes, "contaminant" means a material not naturally occurring in ambient air and/or a material naturally occurring in air but present at a concentration above that found in ambient air. Thus, the present invention scrubs (or treats) air for the purpose of returning it to its ambient composition. Also disclosed herein is a process for the photocatalytic destruction of contaminants from an air stream wherein the contaminated air stream is passed into a control cell or contact zone in which is disposed a photocatalytic aerogel and exposing said aerogel to ultraviolet (UV) radiation for photocatalytically destroying the adsorbed contaminant, and withdrawing from said cell an exhaust air stream depleted in said contaminant.

    Abstract translation: 公开了一种从被污染的气流中分离蒸气或气态污染物的方法。 该方法包括以下步骤:(a)将所述被污染的空气通入接触区,其中设置有气溶胶材料,所述气凝胶材料能够从空气中选择吸附所述污染物,并且其中使所述污染空气与气凝胶材料接触; 和(b)从所述区域中抽出所述污染物的空气。 为了目前的目的,“污染物”是指在环境空气和/或天然存在于空气中而不是天然存在的物质,其浓度高于环境空气中的浓度。 因此,本发明为了将其返回到其环境组成的目的而擦洗(或处理)空气。 本文还公开了一种用于从空气流中光催化破坏污染物的方法,其中将污染的空气流通入控制电池或接触区域,其中设置光催化气凝胶,并将所述气凝胶暴露于紫外线(UV)辐射用于光催化破坏 吸收的污染物,并从所述电池中排出在所述污染物中耗尽的排气流。

    Coal desulfurization using bacteria adaptation and bacterial
modification of pyrite surfaces
    5.
    发明授权
    Coal desulfurization using bacteria adaptation and bacterial modification of pyrite surfaces 失效
    使用细菌适应和黄铁矿表面细菌修饰的煤脱硫

    公开(公告)号:US4775627A

    公开(公告)日:1988-10-04

    申请号:US854509

    申请日:1986-04-22

    CPC classification number: C12R1/01 B03B1/00 B03B9/005 B03D1/02 C10L9/00

    Abstract: The invention relates to the desulfurization of high sulfur coal, and specifically to the removal of pyrite from high sulfur coal via separation processes based on relative hydrophobicity. The surfaces of the pyrite particles are modified so as to be more hydrophilic by pre-conditioning of the coal with a culture of thiophilic bacteria such as Thiobacillus ferroxidans, and the coal is then subjected to the separation process. The bacterial culture is preadapted to pyrite and to the pyrite surface modification step conditions for a period of several weeks which allows the commercial preconditioning step to be accomplished in less than one hour and typically in five to fifteen minutes.

    Abstract translation: 本发明涉及高硫煤的脱硫,具体涉及通过基于相对疏水性的分离方法从高硫煤中除去黄铁矿。 黄铁矿颗粒的表面被修饰,以便通过用硫酸杆菌(Thiobacillus ferroxidans)等嗜氧性细菌的培养物对煤进行预处理而使其更亲水,然后对煤进行分离。 将细菌培养物预先置于黄铁矿和黄铁矿表面改性步骤条件下进行数周,这允许商业预处理步骤在少于1小时内,通常在5至15分钟内完成。

    Polymeric aerogel fibers and fiber webs
    7.
    发明授权
    Polymeric aerogel fibers and fiber webs 有权
    聚合气凝胶纤维和纤维网

    公开(公告)号:US09540495B2

    公开(公告)日:2017-01-10

    申请号:US14727905

    申请日:2015-06-02

    Applicant: Yosry A. Attia

    Inventor: Yosry A. Attia

    Abstract: Polyethylene aerogels and aerogel fiber webs have a high degree of molecular alignment and interconnected fibers, which offer good mechanical strength and high porosity with open interconnected three-dimensional pore structure of the aerogel fibers. The high porosity of the aerogel fibers forming the web, offer a distinct advantage over solid fibers and fiber webs formed from polymer melts, or other non-gel form of polymer solutions. In this procedure, the polymer in solution is made into cross-linked gel with three-dimensional open pore structure before introducing it to the fiber web making process.

    Abstract translation: 聚乙烯气凝胶和气凝胶纤维网具有高度的分子取向和互连的纤维,其提供良好的机械强度和高孔隙率,其中气凝胶纤维具有开放的互连的三维孔结构。 形成纤维网的气凝胶纤维的高孔隙率比固体纤维和由聚合物熔体或其它非凝胶形式的聚合物溶液形成的纤维网具有显着的优点。 在该方法中,将溶液中的聚合物制成具有三维开孔结构的交联凝胶,然后将其引入纤维网制备过程。

    Process for producing a metalliferous concentrate from a particulate
feed material
    8.
    发明授权
    Process for producing a metalliferous concentrate from a particulate feed material 失效
    从颗粒饲料中生产含金属浓缩物的方法

    公开(公告)号:US4512879A

    公开(公告)日:1985-04-23

    申请号:US515574

    申请日:1983-07-20

    CPC classification number: B03B9/00 B07B9/00

    Abstract: A concentrate containing precious metals is produced from a particulate feed material containing particles of various sizes by a size fractionation step, a gravity separation step performed on each size fraction separately, a magnetic separation step and a second gravity separation step. The process is especially intended for separating gold and other metals from so-called "black sand" placer deposits.

    Abstract translation: 含有贵金属的浓缩物通过尺寸分级步骤,分别对每个尺寸级分进行的重力分离步骤,磁分离步骤和第二重力分离步骤由含有各种尺寸的颗粒的颗粒状进料进行制备。 该方法特别用于将金和其他金属与所谓的“黑砂”沉积物分离。

    Polyethylene aerogel and method of production
    9.
    发明授权
    Polyethylene aerogel and method of production 有权
    聚乙烯气凝胶及其生产方法

    公开(公告)号:US09512286B2

    公开(公告)日:2016-12-06

    申请号:US14700387

    申请日:2015-04-30

    Applicant: Yosry A. Attia

    Inventor: Yosry A. Attia

    Abstract: A method for making polyethylene aerogels, including high molecular weight aerogels, commences by in a hydrocarbon solvent (e.g., toluene or benzene) in which polyethylene is insoluble at room temperature, adding polyethylene to the solvent heated to a temperature at which said polyethylene is soluble to form a reaction mixture. A free-radical catalyst is added to the reaction mixture and the reaction mixture is held until the desired gelation of the polyethylene has been achieved. The reaction mixture is cooled to about room temperature; and the hydrocarbon solvent is replaced with a gas (e.g., CO2 or air) to form the polyethylene aerogel. Optionally, the cooled reaction mixture can be contacted with an anti-solvent for polyethylene to replace the hydrocarbon solvent with the anti-solvent. Silica aerogel particles can be encapsulated in polyethylene aerogel by adding the particles to the polyethylene gelation reaction mixture.

    Abstract translation: 制备聚乙烯气凝胶的方法,包括高分子量气凝胶,在烃溶剂(如甲苯或苯)中开始,其中聚乙烯在室温下不溶解,加入聚乙烯加热至所述聚乙烯溶解温度的溶剂 以形成反应混合物。 向反应混合物中加入自由基催化剂,并保持反应混合物,直至达到所需的聚乙烯凝胶化。 将反应混合物冷却至约室温; 并且用气体(例如CO 2或空气)代替烃溶剂以形成聚乙烯气凝胶。 任选地,冷却的反应混合物可与用于聚乙烯的反溶剂接触以用抗溶剂代替烃溶剂。 通过将颗粒加入到聚乙烯凝胶化反应混合物中,可以将二氧化硅气凝胶颗粒包封在聚乙烯气凝胶中。

    Polymeric Aerogel Fibers and Fiber Webs
    10.
    发明申请
    Polymeric Aerogel Fibers and Fiber Webs 审中-公开
    聚合物气凝胶纤维和纤维网

    公开(公告)号:US20150259499A1

    公开(公告)日:2015-09-17

    申请号:US14727905

    申请日:2015-06-02

    Applicant: Yosry A. Attia

    Inventor: Yosry A. Attia

    Abstract: Polyethylene aerogels and aerogel fiber webs have a high degree of molecular alignment and interconnected fibers, which offer good mechanical strength and high porosity with open interconnected three-dimensional pore structure of the aerogel fibers. The high porosity of the aerogel fibers forming the web, offer a distinct advantage over solid fibers and fiber webs formed from polymer melts, or other non-gel form of polymer solutions. In this procedure, the polymer in solution is made into cross-linked gel with three-dimensional open pore structure before introducing it to the fiber web making process.

    Abstract translation: 聚乙烯气凝胶和气凝胶纤维网具有高度的分子取向和互连的纤维,其提供良好的机械强度和高孔隙率,其中气凝胶纤维具有开放的相互连接的三维孔结构。 形成纤维网的气凝胶纤维的高孔隙率比固体纤维和由聚合物熔体或其它非凝胶形式的聚合物溶液形成的纤维网具有显着的优点。 在该方法中,将溶液中的聚合物制成具有三维开孔结构的交联凝胶,然后将其引入纤维网制备过程。

Patent Agency Ranking