专利检索 ap:("Washington University" OR "Disarm Therapeutics, Inc.") AND inv:"Aaron Diantonio" 第 1 页

1.

发明授权
Inhibitors of SARM1 NADase activity and uses thereof 有权

公开(公告)号：US11903935B2

公开(公告)日：2024-02-20

申请号：US17508321

申请日：2021-10-22

申请人： Washington University , Disarm Therapeutics, Inc.

发明人： Jeffrey Milbrandt , Kow Essuman , Yo Sasaki , Aaron Diantonio , Xianrong Mao , Rajesh Devraj , Raul Eduardo Krauss , Robert Owen Hughes

IPC分类号： A61K31/4439 , A61K47/55 , A61K47/52 , A61P25/28 , A61K33/243 , A61K31/047 , A61K31/145 , A61K31/198 , A61K31/41 , A61K31/437 , A61K31/4375 , A61K31/444 , A61K31/4535 , A61K31/566 , A61K31/7048 , A61K31/7084 , A61K33/245 , A61K33/28 , A61K33/30

CPC分类号： A61K31/4439 , A61K31/047 , A61K31/145 , A61K31/198 , A61K31/41 , A61K31/437 , A61K31/4375 , A61K31/444 , A61K31/4535 , A61K31/566 , A61K31/7048 , A61K31/7084 , A61K33/243 , A61K33/245 , A61K33/28 , A61K33/30 , A61K47/52 , A61K47/55 , A61P25/28

摘要： The present disclosure provides compounds useful as inhibitors of SARM1 NADase activity, compositions thereof, and methods of using the same. The present disclosure provides compounds useful for treating a neurodegenerative or neurological disease or disorder, compositions thereof, and methods of using the same.