公开(公告)号：US20040204646A1

公开(公告)日：2004-10-14

申请号：US10836223

申请日：2004-05-03

申请人： V-Target Technologies Ltd.

发明人： Michael Nagler ,  Yoel Zilberstein

IPC分类号： A61B005/05 ,  A61B006/00

CPC分类号： G01T1/161 ,  A61B1/05 ,  A61B1/31 ,  A61B5/0035 ,  A61B5/06 ,  A61B5/415 ,  A61B5/418 ,  A61B6/4057 ,  A61B6/425 ,  A61B6/4258

摘要： An intracorporeal-imaging head, is provided, which combines at least optical and radioactive-emission imaging, possibly also with high-resolution position tracking. The radioactive-emission-imaging probe has a wide-aperture, or coarse collimator, for high count-rate efficiency; nevertheless, the high-resolution position tracking ensures high resolution of the radioactive-emission image. Specifically, wide-aperture collimation-deconvolution algorithms are provided, for obtaining a high-efficiency, high resolution image of a radioactive-emission source, by scanning the radioactive-emission source with a probe of a wide-aperture collimator, and at the same time, monitoring the position of the radioactive-emission probe, at very fine time intervals, to obtain the equivalence of fine-aperture collimation. The blurring effect of the wide aperture is then corrected mathematically. The intracorporeal-imaging head may further include ultrasound and MRI imagers, as well as a surgical instrument, such as a biopsy needle, a knife, a cryosurgery device, a resection wire, a laser ablation device, an ultrasound ablation device, other devices for localized radiation ablations, devices for implanting brachytherapy seeds, and other minimally invasive devices. According to another embodiment, an intracorporeal-detecting head is provided, which combines at least optical and radioactive-emission detectors, for a nullYes or Nonull type detection, by the at least two modalities.

摘要翻译： 提供体内成像头，其至少结合光学和放射性发射成像，可能还具有高分辨率位置跟踪。 放射性发射成像探针具有宽孔径或粗略的准直器，以实现高计数率效率; 然而，高分辨率位置跟踪确保了放射性发射图像的高分辨率。 具体地说，提供宽孔径准直 - 去卷积算法，用于通过用宽孔径准直器的探头扫描放射性发射源，并且在相同的情况下获得放射性发射源的高效率高分辨率图像 时间，以非常精细的时间间隔监测放射性发射探头的位置，以获得细孔准直的等效性。 然后在数学上校正宽光圈的模糊效果。 体内成像头可以进一步包括超声和MRI成像仪，以及手术器械，例如活检针，刀，冷冻手术装置，切除线，激光消融装置，超声消融装置，用于 局部放射线消融，用于植入近距离放射治疗种子的装置和其它微创装置。 根据另一个实施例，提供一种体内检测头，其通过至少两种方式将至少光学和放射性发射检测器组合为“是或否”型检测。