公开(公告)号：US09022993B2

公开(公告)日：2015-05-05

申请号：US13509602

申请日：2010-12-06

申请人： Uwe Dasbach ,  Steffen Raab ,  Marianne Rottluff

发明人： Uwe Dasbach ,  Steffen Raab ,  Marianne Rottluff

IPC分类号： A61M5/00 ,  A61M5/315 ,  A61M5/24 ,  A61M5/48 ,  A61M5/31

CPC分类号： A61M5/3156 ,  A61M5/24 ,  A61M5/31555 ,  A61M5/31585 ,  A61M5/31593 ,  A61M5/482 ,  A61M2005/3103 ,  A61M2005/3126

摘要： A drive assembly for a drug delivery device is presented having a housing with a proximal end and a distal end, a drive member, and a piston rod. A longitudinal axis extends between the proximal end and the distal end and the piston rod is axially moveable relative to the housing. The piston rod has a guide track and the drive member has a guide piece disposed and movable in the guide track. The guide track is configured with at least one section which is oblique relative to the longitudinal axis and defines a displacement for dispensing a single pre-set dose of medication during a relative movement between the guide piece and the piston rod when the guide piece cooperates with the oblique section between a distal final area of the oblique section and a proximal final area of the oblique section.

摘要翻译： 本发明提供了一种用于药物输送装置的驱动组件，其具有具有近端和远端的壳体，驱动构件和活塞杆。 纵向轴线在近端和远端之间延伸，并且活塞杆相对于壳体可轴向移动。 活塞杆具有导轨，并且驱动构件具有设置并可在引导轨道中移动的引导件。 所述导轨配置有至少一个相对于所述纵向轴线倾斜的部分，并且当所述导向件与所述导向件与所述活塞杆配合时在所述导向件和所述活塞杆之间的相对运动期间限定用于分配单个预设剂量的药物的位移 倾斜部分的远端最终区域与倾斜部分的近端部区域之间的倾斜部分。

公开(公告)号：US20130018327A1

公开(公告)日：2013-01-17

申请号：US13509602

申请日：2010-12-06

申请人： Uwe Dasbach ,  Steffen Raab ,  Marianne Rottluff

发明人： Uwe Dasbach ,  Steffen Raab ,  Marianne Rottluff

IPC分类号： A61M5/315

CPC分类号： A61M5/3156 ,  A61M5/24 ,  A61M5/31555 ,  A61M5/31585 ,  A61M5/31593 ,  A61M5/482 ,  A61M2005/3103 ,  A61M2005/3126

摘要： Drive assembly for a drug delivery device, comprising a housing with a proximal end and a distal end, a drive member, and a piston rod. A longitudinal axis (A) extends between the proximal end and the distal end. The piston rod is axially moveable relative to the housing. The piston rod comprises a guide track. The drive member comprises a guide piece being disposed and being movable in the guide track. The guide track comprises at least one section which is oblique relative to the longitudinal axis (A) and defining a displacement for dispensing a single pre-set dose of medication during a relative movement between the guide piece and the piston rod when the guide piece cooperates with the oblique section between a distal final area of the oblique section and a proximal final area of the oblique section. The pitch of the at least one oblique section decreases from the distal final area to the proximal final area. Drug delivery device with a drive assembly, wherein a medication containing cartridge is coupled to the piston rod in a manner to dispense the medication.

摘要翻译： 用于药物输送装置的驱动组件，包括具有近端和远端的壳体，驱动构件和活塞杆。 纵向轴线（A）在近端和远端之间延伸。 活塞杆相对于壳体可轴向移动。 活塞杆包括导轨。 驱动构件包括布置并可在导轨中移动的引导件。 所述导轨包括至少一个相对于所述纵向轴线（A）倾斜的部分，并且当所述导向件协作时，所述至少一个部分在所述导向件和所述活塞杆之间的相对运动期间限定用于分配单个预设剂量的药物的位移 其中倾斜部分的远端部分与倾斜部分的近端部分之间的倾斜部分。 至少一个倾斜部分的间距从远端最终区域减小到近端最终区域。 具有驱动组件的药物递送装置，其中药物容纳药筒以分配药物的方式联接到活塞杆。

公开(公告)号：US09737666B2

公开(公告)日：2017-08-22

申请号：US13504296

申请日：2010-11-01

申请人： Philippe Nzike ,  Steffen Raab ,  Uwe Dasbach ,  Uwe Boeser ,  Ulrich Bruggemann ,  Brice Ulrich Tchouadje ,  Kevin Igor Youmbi Ngatchou

发明人： Philippe Nzike ,  Steffen Raab ,  Uwe Dasbach ,  Uwe Boeser ,  Ulrich Bruggemann

IPC分类号： A61M5/315 ,  A61M5/24

CPC分类号： A61M5/31535 ,  A61M5/24 ,  A61M5/31555 ,  A61M5/31556 ,  A61M5/31585 ,  A61M2005/2407 ,  A61M2205/581 ,  A61M2205/582

摘要： An assembly for a drug delivery device is disclosed. An example assembly includes a housing, a rotation member, a drive member, and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.

公开(公告)号：US09078973B2

公开(公告)日：2015-07-14

申请号：US13258151

申请日：2010-03-31

申请人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach ,  Udo Stauder

发明人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach ,  Udo Stauder

IPC分类号： A61M5/31 ,  A61M5/32

CPC分类号： A61M5/3129 ,  A61M5/3135 ,  A61M5/321 ,  A61M2005/3139

摘要： A drug delivery device comprises an outer housing rollable around a rotation axis and at least one stop member. The stop member protrudes radially from the outer housing of the drug delivery device and is configured to prevent rolling movement of the drug delivery device along a predetermined surface. The outer housing comprises a main housing and a dose member. The dose member is movable with respect to the main housing when setting and/or delivering a dose of a drug. The stop member comprises a first part and a second part, wherein the first part is arranged on the main housing and the second part is arranged on the dose member.

摘要翻译： 药物输送装置包括围绕旋转轴线可滚动的外壳体和至少一个止动件。 止动构件从药物输送装置的外壳径向地突出并且构造成防止药物输送装置沿着预定表面的滚动运动。 外壳包括主壳体和剂量构件。 当设置和/或递送药物的剂量时，剂量构件可相对于主壳体移动。 止挡构件包括第一部分和第二部分，其中第一部分布置在主壳体上，并且第二部分布置在剂量构件上。

公开(公告)号：US20130110054A1

公开(公告)日：2013-05-02

申请号：US13509601

申请日：2010-12-06

申请人： Steffen Raab ,  Uwe Dasbach

发明人： Steffen Raab ,  Uwe Dasbach

IPC分类号： A61M5/315

CPC分类号： A61M5/31586 ,  A61M5/3146 ,  A61M5/31501 ,  A61M5/31541 ,  A61M5/31555 ,  A61M5/31556 ,  A61M5/3156 ,  A61M5/31573 ,  A61M5/31575 ,  A61M5/31585 ,  A61M5/31593

摘要： A drive assembly for a drug delivery device, comprising a housing with a proximal end and a distal end, and a longitudinal axis (A) extending between the proximal end and the distal end, a rotation sleeve being rotatable relative to the housing, and a piston rod being axially moveable relative to the housing. The piston rod is in mechanical cooperation with the rotation sleeve to be rotatable and moveable in the distal direction relative to the housing when the rotation sleeve rotates in a first direction (D1) and to be stationary in axial direction relative to the housing when the rotation sleeve rotates in a second direction (D2) opposite to the first direction (D1).

摘要翻译： 一种用于药物输送装置的驱动组件，包括具有近端和远端的壳体，以及在近端和远端之间延伸的纵向轴线（A），旋转套筒可相对于壳体旋转，并且 活塞杆相对于壳体可轴向移动。 当旋转套筒沿第一方向（D1）旋转时，活塞杆与旋转套筒机械协作以相对于壳体在远端方向上可旋转并且可移动，并且当旋转轴线相对于壳体在轴向方向上静止时 套筒沿与第一方向（D1）相反的第二方向（D2）旋转。

公开(公告)号：US20120172818A1

公开(公告)日：2012-07-05

申请号：US13254087

申请日：2010-03-31

申请人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach

发明人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach

IPC分类号： A61M5/315 ,  A61M5/31

CPC分类号： A61M5/1452 ,  A61M5/31511 ,  A61M5/31555 ,  A61M5/31585 ,  A61M2205/0222

摘要： A first movable element (4) and a second movable element (7) of a mechanism in a medical device are arranged in such a manner that, during an operation of the mechanism, a surface of the first element slides on a surface of the second element. The first element and the second element are formed from materials providing a coefficient of sliding friction of said surfaces on one another of less than 0.14 at a relative velocity of 2 mm per second.

摘要翻译： 医疗装置中的机构的第一可移动元件（4）和第二可移动元件（7）以这样的方式设置，使得在机构的操作期间，第一元件的表面在第二元件 元件。 第一元件和第二元件由以相对于每秒2mm的速度提供所述表面彼此之间小于0.14的滑动摩擦系数的材料形成。

公开(公告)号：US20120165738A1

公开(公告)日：2012-06-28

申请号：US13203599

申请日：2010-03-31

申请人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach

发明人： Michael Harms ,  Steffen Raab ,  Uwe Dasbach

IPC分类号： A61M5/178 ,  B32B37/06

CPC分类号： B29C65/14 ,  B23K26/22 ,  B23K26/282 ,  B23K2101/06 ,  B29C65/1435 ,  B29C65/1441 ,  B29C65/1635 ,  B29C65/1654 ,  B29C65/1677 ,  B29C65/565 ,  B29C65/64 ,  B29C65/66 ,  B29C65/7814 ,  B29C65/7855 ,  B29C66/1122 ,  B29C66/1142 ,  B29C66/124 ,  B29C66/21 ,  B29C66/5344 ,  B29C66/547 ,  B29C66/612 ,  B29C66/73115 ,  B29C66/73116 ,  B29C66/73921 ,  B29C66/742 ,  B29C66/8262 ,  B29K2705/00 ,  B29L2031/7544

摘要： Method for manufacturing a composite work piece for a drug delivery device, comprising the steps: Providing a first work piece part 1 and a second work piece part 2, arranging both work piece parts 1, 2 with respect to each other in such a way that both work piece parts 1, 2 are in mechanical contact with one another in a contact area 3, irradiating a surface of the first work piece part 1 with electromagnetic radiation, thereby softening the first work piece part 1 and/or the second work piece part 2 in a region adjacent to the contact area 3, and joining the first work piece part 1 to the second work piece part 2 in the contact area 3 for the composite work piece. Furthermore, a composite work piece for a drug delivery device is provided.

摘要翻译： 一种药物输送装置用复合制品的制造方法，其特征在于，具备：第一工件部件1和第二工件部件2，使工件零件1,2彼此相对配置， 两个工件部件1,2在接触区域3中彼此机械接触，用电磁辐射照射第一工件部件1的表面，从而软化第一工件部件1和/或第二工件部件 2在与接触区域3相邻的区域中，并且将第一工件部件1连接到用于复合工件的接触区域3中的第二工件部件2。 此外，提供了用于药物输送装置的复合工件。

公开(公告)号：US20120160723A1

公开(公告)日：2012-06-28

申请号：US13254096

申请日：2010-03-31

申请人： Michael Harms ,  Steffen Raab ,  Udo Stauder ,  Volker Korger ,  Uwe Dasbach ,  Caroline Stephan

发明人： Michael Harms ,  Steffen Raab ,  Udo Stauder ,  Volker Korger ,  Uwe Dasbach ,  Caroline Stephan

IPC分类号： A61M5/00 ,  B65D25/10 ,  F16L3/08

CPC分类号： A61M5/003 ,  A61M5/002

摘要： A fixing means (1) for a drug delivery device (6) comprises at least two clip elements (2) for releasably securing at least one drug delivery device (6) to said fixing means (1), wherein each of the two clip elements (2) comprises a flexible holding member (3) and wherein the clip elements (2) share one flexible holding member (4) with each other.

摘要翻译： 用于药物输送装置（6）的固定装置（1）包括至少两个夹子元件（2），用于将至少一个药物输送装置（6）可释放地固定到所述固定装置（1）上，其中两个夹子元件 （2）包括柔性保持构件（3），并且其中夹子元件（2）彼此共享一个柔性保持构件（4）。

公开(公告)号：US20120101452A1

公开(公告)日：2012-04-26

申请号：US13258160

申请日：2010-03-31

申请人： Michael Harms ,  Volker Korger ,  Uwe Dasbach ,  Steffen Raab

发明人： Michael Harms ,  Volker Korger ,  Uwe Dasbach ,  Steffen Raab

IPC分类号： A61M5/315

CPC分类号： A61M5/31543 ,  A61M5/24 ,  A61M5/31525 ,  A61M5/31528 ,  A61M2005/2481

摘要： A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated.

摘要翻译： 身体中的机构用于驱动活塞杆，并且包括用于在输送药物的同时引导活塞杆相对于身体的运动的装置。 提供了用于将活塞杆从用于引导运动的装置释放的另外的装置，从而使活塞杆能够复位到起始位置，特别是在容器被排空并被重新填充之后。 该装置的构造使得活塞杆的复位变得容易。

公开(公告)号：US20120083748A1

公开(公告)日：2012-04-05

申请号：US13258158

申请日：2010-03-31

申请人： Michael Harms ,  Volker Korger ,  Uwe Dasbach ,  Steffen Raab

发明人： Michael Harms ,  Volker Korger ,  Uwe Dasbach ,  Steffen Raab

IPC分类号： A61M5/315

CPC分类号： A61M5/31525 ,  A61M5/178 ,  A61M5/315 ,  A61M5/31543 ,  A61M2005/3115

摘要： A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated by a stop element inhibiting a reversal of the movement of the piston rod when being reset.

摘要翻译： 身体中的机构用于驱动活塞杆，并且包括用于在输送药物的同时引导活塞杆相对于身体的运动的装置。 提供了用于将活塞杆从用于引导运动的装置释放的另外的装置，从而使活塞杆能够复位到起始位置，特别是在容器被排空并被重新填充之后。 该装置的结构是这样一种方式：活塞杆的复位由止动件有助于在复位时阻止活塞杆运动反转。