公开(公告)号：US20240298689A1

公开(公告)日：2024-09-12

申请号：US18657307

申请日：2024-05-07

申请人： University of Southern California

发明人： Valter D. LONGO ,  Chia-Wei CHENG

IPC分类号： A23L33/00

CPC分类号： A23L33/30 ,  A23L33/40 ,  A23V2002/00

摘要： A method of alleviating symptoms of, or treating, pancreatic beta-cell damage in a subject includes a step of identifying a subject having pancreatic beta-cell damage. Multiple cycles of a diet protocol are administered to the subject. The diet protocol includes administering of a fasting mimicking diet and a re-feeding diet where the fasting mimicking diet is provided for a first time period and the re-feeding diet is provided for a second time period.

公开(公告)号：US20210145038A1

公开(公告)日：2021-05-20

申请号：US17162809

申请日：2021-01-29

申请人： UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： Valter D. LONGO ,  Chia-Wei CHENG

IPC分类号： A23L33/00

摘要： A method of alleviating symptoms of, or treating, pancreatic beta-cell damage in a subject includes a step of identifying a subject having pancreatic beta-cell damage. Multiple cycles of a diet protocol are administered to the subject. The diet protocol includes administering of a fasting mimicking diet and a re-feeding diet where the fasting mimicking diet is provided for a first time period and the re-feeding diet is provided for a second time period.

公开(公告)号：US20210177032A1

公开(公告)日：2021-06-17

申请号：US17182676

申请日：2021-02-23

申请人： UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： Valter D. LONGO ,  Chia-Wei CHENG ,  Sebastian BRANDHORST ,  Min WEI

IPC分类号： A23L33/00 ,  A61K45/00 ,  A23L29/30 ,  A23L33/115 ,  A23L33/175 ,  A23L33/17 ,  A23L33/16 ,  A23L33/15 ,  A23L33/155

摘要： A method includes a step of identifying a subject in need of diet modification; and administering a first diet to the subject for a first time period. The first diet provides 4.5 to 7 kilocalories per pound of subject for a first day and 3 to 5 kilocalories per pound of subject per day for a second to fifth day of the first diet. The first diet includes less than 30 g of sugar on the first day; less than 20 g of sugar on the second to fifth days; less than 28 g of proteins on the first day; less than 18 g of proteins on days the second to fifth days; 20 to 30 grams of monounsaturated fats on the first day; 10 to 15 grams of monounsaturated fats on the second to fifth days; and between 6 and 10 grams of polyunsaturated fats on the first day.

公开(公告)号：US20150004280A1

公开(公告)日：2015-01-01

申请号：US14320996

申请日：2014-07-01

申请人： UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： Valter D. LONGO ,  Chia-Wei CHENG

IPC分类号： A23L1/29

CPC分类号： A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A23V2200/328

摘要： A method of alleviating symptoms of, or treating, pancreatic beta-cell damage in a subject includes a step of identifying a subject having pancreatic beta-cell damage. Multiple cycles of a diet protocol are administered to the subject. The diet protocol includes administering of a fasting mimicking diet and a re-feeding diet where the fasting mimicking diet is provided for a first time period and the re-feeding diet is provided for a second time period.

摘要翻译： 减轻受试者胰腺β细胞损伤症状或治疗胰腺β细胞损伤的方法包括鉴定具有胰腺β-细胞损伤的受试者的步骤。 对受试者施用饮食方案的多个周期。 饮食方案包括施用禁食模拟饮食和再喂食饮食，其中第一时间提供禁食模拟饮食，并且再次喂养饮食提供第二时间段。