公开(公告)号：US10016759B2

公开(公告)日：2018-07-10

申请号：US14683316

申请日：2015-04-10

申请人： University of Macau

发明人： Cheng Dong ,  Tianlan Chen ,  Jie Gao ,  Yanwei Jia ,  Pui-In Mak ,  Mang-I Vai ,  Rui Paulo da Silva Martins

IPC分类号： B01L3/00 ,  G01N27/447

CPC分类号： B01L3/502784 ,  B01L2200/143 ,  B01L2300/025 ,  B01L2300/0887 ,  B01L2400/0427

摘要： According to one aspect of the present disclosure, a control-engaged electrode-driving method for droplet actuation is provided. The method includes, a first pulse is provided to a first electrode for kicking off a droplet till a centroid of the droplet reaching a centroid of the first electrode. A second pulse is provided to a second electrode when a leading edge of the droplet reaching the second electrode.

公开(公告)号：US09751083B2

公开(公告)日：2017-09-05

申请号：US14680671

申请日：2015-04-07

申请人： University of Macau

发明人： Jie Gao ,  Tianlan Chen ,  Cheng Dong ,  Yanwei Jia ,  Pui-In Mak ,  Mang-I Vai ,  Rui Paulo da Silva Martins

IPC分类号： G01N27/27 ,  B01L3/00 ,  G01N27/447

CPC分类号： B01L3/502792 ,  B01L2200/143 ,  B01L2300/025 ,  B01L2300/0887 ,  B01L2400/0427 ,  G01N27/44704 ,  G01N27/44756 ,  G01N27/44791

摘要： According to one aspect of the present disclosure, a digital microfluidic system is provided. The digital microfluidic system includes a device, a control electronics, a field programmed gate array (FPGA), and a computer. The device includes a droplet on an electrode array, where the electrode array includes a plurality of electrodes. The control electronics connects to the device and provides an actuation pulse to the electrodes, where the control electronics generates a capacitance-derived frequency signal. The FPGA connects to the control electronics and collects the capacitance-derived frequency signal. The computer connects to the FPGA, the computer uses a frequency of the capacitance-derived frequency signal to calculate a precise droplet position and generates a duration voltage signal.

公开(公告)号：US09808800B2

公开(公告)日：2017-11-07

申请号：US14683402

申请日：2015-04-10

申请人： University of Macau

发明人： Tianlan Chen ,  Cheng Dong ,  Jie Gao ,  Yanwei Jia ,  Pui-In Mak ,  Mang-I Vai ,  Rui Paulo da Silva Martins

IPC分类号： G01N27/447 ,  B01L3/00 ,  F04B19/00

CPC分类号： B01L3/50273 ,  B01L3/502792 ,  B01L2300/088 ,  B01L2300/089 ,  B01L2400/0427 ,  F04B19/006

摘要： According to one aspect of the present disclosure, a control-engaged electrode-driving method for droplet actuation is provided. The method includes, a first voltage is provided to a first electrode for licking off a droplet. A second voltage is naturally discharged to a third voltage for maintaining a droplet movement. A fourth voltage is provided to the first electrode for accelerating the droplet. Naturally discharging from the second voltage to the third voltage and providing the fourth voltage to the first electrode are repeated. The first voltage is provided to a second electrode when a centroid of the droplet reaching a centroid of the first electrode. Naturally discharging from the second voltage to the third voltage and providing the fourth voltage to the second electrode are repeated.

公开(公告)号：US11618025B2

公开(公告)日：2023-04-04

申请号：US16648009

申请日：2018-08-01

申请人： University of Macau

发明人： Yanwei Jia ,  Haoran Li ,  Ren Shen ,  Cheng Dong ,  Tianlan Chen ,  Jie Gao ,  Pui-ln Mak ,  Rui Paulo da Silva Martins

IPC分类号： B01L3/00 ,  G01N33/53

摘要： Provided is an apparatus, system and method for on-chip microfluids dispensing. The apparatus comprising a substrate; a plurality of first electrodes arranged one next to another on the substrate; a dielectric layer above and enclosing the plurality of first electrodes; and a second electrode on the substrate, wherein each of the plurality of first electrodes is in electric communication with a respective first driving signal input; wherein the second electrode is in electric communication with a second driving signal input; wherein the plurality of first electrodes define a continuous fluid path along a longitudinal direction for retaining microfluids, and wherein the second electrode is arranged within the continuous fluid path and defines a jetting position and an adjacent mixing position within the continuous fluid path.