知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

21 条记录 (耗时 0.022 秒)

    Methods of Orienting Multifilament Yarn and Monofilaments of Poly-4-Hydroxybutyrate and Copolymers Thereof
    4.
    发明申请
    Methods of Orienting Multifilament Yarn and Monofilaments of Poly-4-Hydroxybutyrate and Copolymers Thereof 有权
    定向聚-4-羟基丁酸酯及其共聚物的多丝纱线和单丝的方法

    公开(公告)号：US20160166727A1

    公开(公告)日：2016-06-16

    申请号：US14964985

    申请日：2015-12-10

    申请人： Tepha, Inc.

    发明人： Amit Ganatra ,  Fabio Felix ,  Bhavin Shah ,  Matthew Bernasconi ,  Said Rizk ,  David P. Martin ,  Simon F. Williams

    IPC分类号： A61L17/10 ,  B29C55/00 ,  D01F8/14 ,  A61L31/06 ,  A61L31/14

    CPC分类号： D01F6/625 ,  A61L17/105 ,  A61L31/06 ,  A61L31/148 ,  B29C55/005 ,  B29K2073/00 ,  B29K2673/00 ,  B29L2031/731 ,  D01D5/08 ,  D01F8/14 ,  D02G3/04 ,  D10B2331/04 ,  D10B2331/041 ,  D10B2401/063 ,  D10B2509/04 ,  D10B2509/08

    摘要： Resorbable multifilament yarns and monofilament fibers including poly-4-hydroxybutyrate and copolymers thereof with high tenacity or high tensile strength have been developed. The yarns and fibers are produced by cold drawing the multifilament yarns and monofilament fibers before hot drawing the yarns and fibers under tension at temperatures above the melt temperature of the polymer or copolymer. These yarns and fibers have prolonged strength retention in vivo making them suitable for soft tissue repairs where high strength and strength retention is required. The multifilament yarns have tenacities higher than 8.1 grams per denier, and in vivo, retain at least 65% of their initial strength at 2 weeks. The monofilament fibers retain at least 50% of their initial strength at 4 weeks in vivo. The monofilament fibers have tensile strengths higher than 500 MPa. These yarns and fibers may be used to make various medical devices for various applications.

    摘要翻译： 已经开发了可再吸收的复丝纱线和包括聚-4-羟基丁酸酯的单丝纤维及其具有高强度或高拉伸强度的共聚物。 在高于聚合物或共聚物的熔融温度的温度下，在拉伸纱线和纤维之前，通过冷拉丝多丝纱线和单丝纤维来生产纱线和纤维。 这些纱线和纤维在体内具有延长的强度保持性，使得它们适用于需要高强度和强度保持性的软组织修复。 复丝纱线具有高于8.1克/旦尼尔的强度，并且在体内，在2周时保持其初始强度的至少65％。 单丝纤维在体内4周时保持其初始强度的至少50％。 单丝纤维的拉伸强度高于500MPa。 这些纱线和纤维可用于制造用于各种应用的各种医疗装置。

    CALENDERED SURGICAL MESHES COMPRISING POLYHYDROXYALKANOATES
    7.
    发明申请
    CALENDERED SURGICAL MESHES COMPRISING POLYHYDROXYALKANOATES 审中-公开

    公开(公告)号：US20190069983A1

    公开(公告)日：2019-03-07

    申请号：US16122305

    申请日：2018-09-05

    申请人： Tepha, Inc.

    发明人： Said Rizk ,  Bhavin Shah ,  David P. Martin ,  Simon F. Williams

    IPC分类号： A61F2/00

    摘要： Calendered surgical meshes comprising polyhydroxyalkanoate polymers have been developed. These meshes, preferably made from poly-4-hydroxybutyrate or copolymer thereof, have a thickness that is between 50 to 99% of the thickness of the mesh prior to calendering, and a burst strength that is not less than 20% of the burst strength of the mesh prior to calendering. The thinner calendered meshes are particularly suitable for surgical applications where a thinner profile mesh with high burst strength is required, and where it is advantageous to have a mesh with a smooth surface. The meshes may be partially or fully resorbable, and are particularly suitable for use in the treatment of pelvic organ prolapse.

    EXPANDABLE ABSORBABLE IMPLANTS FOR BREAST RECONSTRUCTION AND AUGMENTATION
    9.
    发明公开
    EXPANDABLE ABSORBABLE IMPLANTS FOR BREAST RECONSTRUCTION AND AUGMENTATION 审中-公开

    公开(公告)号：US20230165673A1

    公开(公告)日：2023-06-01

    申请号：US18075202

    申请日：2022-12-05

    申请人： Tepha, Inc.

    发明人： Skander Limem ,  Bhavin Shah ,  Said Rizk ,  Matthew Dubois ,  Simon F. Williams

    IPC分类号： A61F2/12 ,  A61F2/00 ,  A61K35/35 ,  A61L27/54 ,  A61B90/00

    CPC分类号： A61F2/12 ,  A61F2/0063 ,  A61K35/35 ,  A61L27/54 ,  A61B90/02 ,  A61B2017/00969

    摘要： Expandable absorbable implants have been developed that are suitable for breast reconstruction following mastectomy. The implants can be implanted in the vicinity of a tissue expander, for example, by suturing to the detached edge of the pectoralis major muscle to function as a pectoralis extender, and used to form a sling for a tissue expander. The implants, which permit tissue-ingrowth and slowly degrade, can be expanded in the breast using a tissue expander in order to form a pocket for a permanent breast implant. After expansion, the tissue expander can be removed and replaced with a permanent breast implant. The expandable implants help reduce patient discomfort resulting from tissue expansion, and avoid the need to use allografts or xenografts to create the pocket for the tissue expander. The expandable absorbable implant preferably comprises poly-4-hydroxybutyrate or copolymer thereof.