专利检索 ap:("THE REGENTS OF THE UNIVERSITY OF MICHIGAN") AND inv:"Liming Shu" 第 1 页

1.

发明申请
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME 审中-公开

公开(公告)号：US20180022697A1

公开(公告)日：2018-01-25

申请号：US15546320

申请日：2016-02-01

申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人： Scott D. Larsen , Akira Abe , Liming Shu , Michael William Wilson , Richard F. Keep , Duxin Sun , James A. Shayman

IPC分类号： C07D207/06 , C07D263/20 , C07D207/10 , C07D295/13 , C07D205/04

CPC分类号： C07D207/06 , A61K31/4015 , C07D205/04 , C07D207/04 , C07D207/09 , C07D207/10 , C07D263/20 , C07D263/24 , C07D295/125 , C07D295/13

摘要： Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the treatment of diseases and conditions wherein inhibition of glucosylceramide synthase provides a benefit, like Gaucher disease and Fabry disease, also are disclosed.

2.

发明申请
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME 有权
标题翻译：胶原蛋白合成酶抑制剂及其治疗方法

公开(公告)号：US20130095089A1

公开(公告)日：2013-04-18

申请号：US13652016

申请日：2012-10-15

申请人： The Regents of The University of Michigan

发明人： Scott Larsen , Akira Abe , Liming Shu , Michael William Wilson , Richard F. Keep , James A. Shayman

IPC分类号： A61K31/4025 , C07D207/09 , A61K31/40 , A61P25/16 , A61P25/00 , A61K48/00 , A61P7/06 , A61P35/00 , A61P13/12 , A61P9/10 , A61P31/00 , A61K38/43 , C07D405/10 , A61P3/10

CPC分类号： A61K45/06 , A61K31/40 , C07D295/125 , C07D295/135 , C07D319/18 , A61K2300/00

摘要： Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the treatment of diseases and conditions wherein inhibition of glucosylceramide synthase provides a benefit, like Gaucher disease and Fabry disease, also are disclosed.

摘要翻译： 披露了葡糖基神经酰胺合成酶抑制剂及其组合物。还公开了使用葡萄糖神经酰胺合成酶抑制剂治疗其中抑制葡萄糖神经酰胺合酶有益的疾病和病症的方法，如戈谢病和法布里病。

3.

发明授权
Glucosylceramide synthase inhibitors and therapeutic methods using the same 有权
标题翻译：葡萄糖神经酰胺合酶抑制剂及其治疗方法

公开(公告)号：US08961959B2

公开(公告)日：2015-02-24

申请号：US13652016

申请日：2012-10-15

申请人： The Regents of the University of Michigan

发明人： Scott Larsen , Akira Abe , Liming Shu , Michael William Wilson , Richard F. Keep , James A. Shayman

IPC分类号： A61K38/43 , A01N43/36 , A61K31/40 , A61K48/00 , A01N33/18 , A01N33/24 , A61K31/045 , C07D405/00 , C07D207/08 , C07D207/46 , C07D295/04 , A61K45/06 , C07D319/18 , C07D295/125 , C07D295/135

CPC分类号： A61K45/06 , A61K31/40 , C07D295/125 , C07D295/135 , C07D319/18 , A61K2300/00

摘要： Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the treatment of diseases and conditions wherein inhibition of glucosylceramide synthase provides a benefit, like Gaucher disease and Fabry disease, also are disclosed.

摘要翻译： 披露了葡糖基神经酰胺合成酶抑制剂及其组合物。还公开了使用葡萄糖神经酰胺合成酶抑制剂治疗其中抑制葡萄糖神经酰胺合酶有益的疾病和病症的方法，如戈谢病和法布里病。

4.

发明授权
Glucosylceramide synthase inhibitors and therapeutic methods using the same 有权

公开(公告)号：US10202340B2

公开(公告)日：2019-02-12

申请号：US15546320

申请日：2016-02-01

申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人： Scott D. Larsen , Akira Abe , Liming Shu , Michael William Wilson , Richard F. Keep , Duxin Sun , James A. Shayman

IPC分类号： A61K31/4015 , C07D207/06 , C07D263/20 , C07D207/04 , C07D263/24 , C07D205/04 , C07D207/09 , C07D207/10 , C07D295/125 , C07D295/13

摘要： Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the treatment of diseases and conditions wherein inhibition of glucosylceramide synthase provides a benefit, like Gaucher disease and Fabry disease, also are disclosed.