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公开(公告)号：US20180268185A1
公开(公告)日：2018-09-20
申请号：US15856539
申请日：2017-12-28
Inventor： Rafael Piestun , Anthony Barsic
CPC classification number: G06K9/00 , G01N21/6458 , G02B21/14 , G02B21/361 , G02B21/367 , G06K9/6807 , G06T7/73 , G06T2200/04 , G06T2207/10016 , G06T2207/10056 , G06T2207/10064 , G06T2207/30242 , H05K999/99
Abstract: Systems, methods, and computer program products are disclosed to localize and/or image a dense array of particles. In some embodiments, a plurality of particles may be imaged using an imaging device. A plurality of point spread function dictionary coefficients of the image may be estimated using a point spread function dictionary; where the point spread function dictionary can include a plurality of spread function responses corresponding to different particle positions. From the point spread function dictionary coefficients the number of particles in the image can be determined. Moreover location of each particle in the image can be determined from the point spread function dictionary coefficients.
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公开(公告)号：US20150192510A1
公开(公告)日：2015-07-09
申请号：US14409397
申请日：2013-06-24
Inventor： Rafael Piestun , Anurag Agrawal , Sean Quirin , Anthony Barsic , Ginni Grover
CPC classification number: G01N15/1429 , G01B11/002 , G01B11/14 , G01B21/16 , G01N15/1456 , G01N21/6458 , G01N2015/0038 , G01N2015/1445
Abstract: Imaging or measurement methods and systems including methods and systems for finding the three-dimensional orientation and position of multiple dipole-like particles and single molecules, methods and systems for generating helical beams and helical spread functions, and methods and systems for super-resolution and super-localization of dense arrays of emitters.
Abstract translation: 成像或测量方法和系统，包括用于发现多个偶极子颗粒和单分子的三维取向和位置的方法和系统，用于产生螺旋波束和螺旋扩散函数的方法和系统，以及用于超分辨率和 密集阵列发射体的超定位。
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公开(公告)号：US10955331B2
公开(公告)日：2021-03-23
申请号：US14409397
申请日：2013-06-24
Inventor： Rafael Piestun , Anurag Agrawal , Sean Quirin , Anthony Barsic , Ginni Grover
Abstract: Imaging or measurement methods and systems including methods and systems for finding the three-dimensional orientation and position of multiple dipole-like particles and single molecules, methods and systems for generating helical beams and helical spread functions, and methods and systems for super-resolution and super-localization of dense arrays of emitters.
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公开(公告)号：US10657346B2
公开(公告)日：2020-05-19
申请号：US15856539
申请日：2017-12-28
Inventor： Rafael Piestun , Anthony Barsic
Abstract: Systems, methods, and computer program products are disclosed to localize and/or image a dense array of particles. In some embodiments, a plurality of particles may be imaged using an imaging device. A plurality of point spread function dictionary coefficients of the image may be estimated using a point spread function dictionary; where the point spread function dictionary can include a plurality of spread function responses corresponding to different particle positions. From the point spread function dictionary coefficients the number of particles in the image can be determined. Moreover location of each particle in the image can be determined from the point spread function dictionary coefficients.
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