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公开(公告)号：US11478131B2
公开(公告)日：2022-10-25
申请号：US16242416
申请日：2019-01-08
Inventor： Marc Chelala , Sritam P. Rout , Maria F. Torres , Kyle R. Cowdrick , David M. Gullotti , Amir Hossein Soltanianzadeh , George Coles , Youseph Yazdi , Pankaj J. Pasricha , Ryan V. Wales , Demetri Monovoukas , John T. Favreau
IPC: A61B1/01 , A61B1/00 , A61B1/005 , A61M25/01 , A61M25/09 , A61B17/00 , A61B17/34 , A61B17/32 , A61B18/00
Abstract: The present disclosure relates generally to the field of medical devices and establishing access to body passageways. In particular, the present disclosure relates to devices, systems and methods to facilitate entry of an endoscopic accessory tool into and/or through patient-specific anatomies. For example, the devices, systems and methods of the present disclosure may transmit mechanical motion to the distal end of an endoscopic accessory tool to facilitate atraumatic access to tortuous or otherwise restricted anatomies.
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Patent Agency Ranking
公开(公告)号：US10772716B2
公开(公告)日：2020-09-15
申请号：US16281620
申请日：2019-02-21
Applicant: THE JOHNS HOPKINS UNIVERSITY
Inventor： Gary Gerstenblith , Jason Benkoski , George Coles , Chao-Wei Hwang , Peter Johnston , Gordon Tomaselli , Robert G. Weiss , Steven P. Schulman , Jeffrey A. Brinker
IPC: A61F2/02 , A61L27/38 , A61L27/54 , A61K35/545 , A61L29/00 , A61L29/16 , C12N5/0775 , A61K35/28 , A61K9/00 , A61L29/14 , A61L31/10 , A61L31/14 , A61L31/16 , A61L27/16 , A61L27/28 , A61L27/56
Abstract: A method for promoting healing of tissue by delivering a bioreactor into a subject is provided. The bioreactor is an enclosed housing with paracrine factor producing cells enclosed within the housing. The housing is impermeable to the paracrine factor producing cells, impermeable to immunological cells outside of the housing, and permeable to paracrine factors produced by the paracrine factor producing cells. The paracrine factors produced by the paracrine factor producing cells are released out of the housing to promote healing of the tissue.
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公开(公告)号：US20190314416A1
公开(公告)日：2019-10-17
申请号：US16281620
申请日：2019-02-21
Applicant: THE JOHNS HOPKINS UNIVERSITY
Inventor： Gary Gerstenblith , Jason Benkoski , George Coles , Chao-Wei Hwang , Peter Johnston , Gordon Tomaselli , Robert G. Weiss , Steven P. Schulman
Abstract: A method for promoting healing of tissue by delivering a bioreactor into a subject is provided. The bioreactor is an enclosed housing with paracrine factor producing cells enclosed within the housing. The housing is impermeable to the paracrine factor producing cells, impermeable to immunological cells outside of the housing, and permeable to paracrine factors produced by the paracrine factor producing cells. The paracrine factors produced by the paracrine factor producing cells are released out of the housing to promote healing of the tissue.
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4.发明申请公开(公告)号：US20190208990A1
公开(公告)日：2019-07-11
申请号：US16242416
申请日：2019-01-08
Inventor： Marc Chelala , Sritam P. Rout , Maria F. Torres , Kyle R. Cowdrick , David M. Gullotti , Amir Hossein Soltanianzadeh , George Coles , Youseph Yazdi , Pankaj J. Pasricha , Ryan V. Wales , Demetri Monovoukas , John T. Favreau
CPC classification number: A61M25/0133 , A61B1/00066 , A61B1/00087 , A61B1/00133 , A61B1/00154 , A61B1/0016 , A61B1/0051 , A61B1/0055 , A61B1/0057 , A61B1/01 , A61B1/018 , A61B1/04 , A61B2017/003 , A61M25/09041
Abstract: The present disclosure relates generally to the field of medical devices and establishing access to body passageways. In particular, the present disclosure relates to devices, systems and methods to facilitate entry of an endoscopic accessory tool into and/or through patient-specific anatomies. For example, the devices, systems and methods of the present disclosure may transmit mechanical motion to the distal end of an endoscopic accessory tool to facilitate atraumatic access to tortuous or otherwise restricted anatomies.
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公开(公告)号：US20230016313A1
公开(公告)日：2023-01-19
申请号：US17947695
申请日：2022-09-19
Inventor： Marc Chelala , Sritam P. Rout , Maria F. Torres , Kyle R. Cowdrick , David M. Gullotti , Amir Hossein Soltanianzadeh , George Coles , Youseph Yazdi , Pankaj J. Pasricha , Ryan V. Wales , Demetri Monovoukas , John T. Favreau
Abstract: The present disclosure relates generally to the field of medical devices and establishing access to body passageways. In particular, the present disclosure relates to devices, systems and methods to facilitate entry of an endoscopic accessory tool into and/or through patient-specific anatomies. For example, the devices, systems and methods of the present disclosure may transmit mechanical motion to the distal end of an endoscopic accessory tool to facilitate atraumatic access to tortuous or otherwise restricted anatomies.
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公开(公告)号：US20170245976A1
公开(公告)日：2017-08-31
申请号：US15467455
申请日：2017-03-23
Applicant: THE JOHNS HOPKINS UNIVERSITY
Inventor： Gary Gerstenblith , Jason Benkoski , Jeffrey Brinker , George Coles , Chao-Wei Hwang , Peter Johnston , Gordon Tomaselli , Robert G. Weiss , Steven P. Schulman
CPC classification number: A61F2/022 , A61K35/28 , A61K35/545 , A61L27/16 , A61L27/28 , A61L27/3834 , A61L27/54 , A61L27/56 , A61L29/00 , A61L29/005 , A61L29/16 , A61L2300/42 , A61L2300/64 , A61L2430/20 , C12N5/0663 , C12N2533/30
Abstract: An implantable bioreactor containing a barrier which is designed to allow the release of cell-derived biomolecules, but restricts the entry of immunologic and other cells, or the egress of the cells contained within the bioreactor. Two broad classes of implantable bioreactors are envisioned, encompassing devices for both systemic delivery of the bio-products and local delivery at the target tissue. Bioreactors of both classes can be implanted via surgery, through percutaneous techniques, or other techniques which effect implantation.
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