公开(公告)号：US09812846B2

公开(公告)日：2017-11-07

申请号：US15140125

申请日：2016-04-27

Applicant: The General Hospital Corporation

Inventor： Seok-Hyun Yun ,  Brett Eugene Bouma ,  Guillermo J. Tearney ,  Johannes Fitzgerald De Boer

IPC: H01S3/08 ,  H01S5/50 ,  H01S5/00 ,  H01S5/14 ,  H01S5/10 ,  A61B5/00 ,  G01J3/02 ,  G01J3/453 ,  G01N21/47 ,  G02B27/48 ,  G01B9/02 ,  G02B6/36 ,  G02B26/12 ,  G02F1/09 ,  G02F1/11 ,  H01S3/00 ,  H01S3/106 ,  G01J9/02 ,  H01S3/105

CPC classification number: H01S5/5045 ,  A61B5/0059 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02002 ,  G01B9/02004 ,  G01B9/02043 ,  G01B9/02075 ,  G01B9/02081 ,  G01B9/02083 ,  G01B9/02084 ,  G01B9/0209 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0264 ,  G01J3/453 ,  G01J9/0215 ,  G01N21/4795 ,  G02B6/3604 ,  G02B26/12 ,  G02B27/48 ,  G02F1/093 ,  G02F1/11 ,  H01S3/0071 ,  H01S3/0078 ,  H01S3/08009 ,  H01S3/08063 ,  H01S3/105 ,  H01S3/1068 ,  H01S5/0071 ,  H01S5/0078 ,  H01S5/1025 ,  H01S5/14 ,  H01S5/141 ,  H01S5/146

Abstract: Exemplary apparatus and method are provided. In particular, an electromagnetic radiation can be emitted with, e.g. a light source arrangement. For example, the light source arrangement can include a cavity and a filter, and a spectrum of the electromagnetic radiation can be controlled, e.g., with such cavity and filter, to have a mean frequency that changes (i) at an absolute rate that is greater than about 100 terahertz per millisecond, and (ii) over a range that is greater than about 10 terahertz. Additionally or alternatively, the light source arrangement can include a frequency shifting device which can shift the mean frequency of the electromagnetic radiation.

公开(公告)号：US20130128274A1

公开(公告)日：2013-05-23

申请号：US13720507

申请日：2012-12-19

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Seok-Hyun Yun ,  Brett Eugene Bouma ,  Guillermo J. Tearney ,  Johannes Fitzgerald De Boer

IPC: G01B9/02

CPC classification number: H01S5/5045 ,  A61B5/0059 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02002 ,  G01B9/02004 ,  G01B9/02043 ,  G01B9/02075 ,  G01B9/02081 ,  G01B9/02083 ,  G01B9/02084 ,  G01B9/0209 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0264 ,  G01J3/453 ,  G01J9/0215 ,  G01N21/4795 ,  G02B6/3604 ,  G02B26/12 ,  G02B27/48 ,  G02F1/093 ,  G02F1/11 ,  H01S3/0071 ,  H01S3/0078 ,  H01S3/08009 ,  H01S3/08063 ,  H01S3/105 ,  H01S3/1068 ,  H01S5/0071 ,  H01S5/0078 ,  H01S5/1025 ,  H01S5/14 ,  H01S5/141 ,  H01S5/146

Abstract: An apparatus and method are provided. In particular, at least one first electro-magnetic radiation may be provided to a sample and at least one second electro-magnetic radiation can be provided to a non-reflective reference. A frequency of the first and/or second radiations varies over time. An interference is detected between at least one third radiation associated with the first radiation and at least one fourth radiation associated with the second radiation. Alternatively, the first electro-magnetic radiation and/or second electro-magnetic radiation have a spectrum which changes over time. The spectrum may contain multiple frequencies at a particular time. In addition, it is possible to detect the interference signal between the third radiation and the fourth radiation in a first polarization state. Further, it may be preferable to detect a further interference signal between the third and fourth radiations in a second polarization state which is different from the first polarization state. The first and/or second electro-magnetic radiations may have a spectrum whose mean frequency changes substantially continuously over time at a tuning speed that is greater than 100 Tera Hertz per millisecond.

公开(公告)号：USRE47675E1

公开(公告)日：2019-10-29

申请号：US15151789

申请日：2016-05-11

Applicant: The General Hospital Corporation

Inventor： Brett Eugene Bouma ,  Seok-Hyun Yun ,  Wang-Yuhl Oh ,  Johannes Fitzgerald De Boer ,  Guillermo J. Tearney

IPC: H01S3/10 ,  G01J3/10 ,  G01B9/02 ,  G01J3/12 ,  G01N21/47 ,  G02B27/48 ,  A61B5/00 ,  G01J9/02 ,  H01S3/08 ,  H01S3/105 ,  H01S5/14 ,  H01S5/40

Abstract: An apparatus and source arrangement for filtering an electromagnetic radiation can be provided which may include at least one spectral separating arrangement configured to physically separate one or more components of the electromagnetic radiation based on a frequency of the electromagnetic radiation. The apparatus and source arrangement may also have at least one continuously rotating optical arrangement which is configured to receive at least one signal that is associated with the one or more components. Further, the apparatus and source arrangement can include at least one beam selecting arrangement configured to receive the signal.

公开(公告)号：US20160320170A1

公开(公告)日：2016-11-03

申请号：US15140125

申请日：2016-04-27

Applicant: The General Hospital Corporation

Inventor： Seok-Hyun Yun ,  Brett Eugene Bouma ,  Guillermo J. Tearney ,  Johannes Fitzgerald De Boer

IPC: G01B9/02 ,  G02B6/36 ,  G02F1/09 ,  G02B26/12 ,  G02F1/11 ,  G01J3/453 ,  H01S3/00

CPC classification number: H01S5/5045 ,  A61B5/0059 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02002 ,  G01B9/02004 ,  G01B9/02043 ,  G01B9/02075 ,  G01B9/02081 ,  G01B9/02083 ,  G01B9/02084 ,  G01B9/0209 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0264 ,  G01J3/453 ,  G01J9/0215 ,  G01N21/4795 ,  G02B6/3604 ,  G02B26/12 ,  G02B27/48 ,  G02F1/093 ,  G02F1/11 ,  H01S3/0071 ,  H01S3/0078 ,  H01S3/08009 ,  H01S3/08063 ,  H01S3/105 ,  H01S3/1068 ,  H01S5/0071 ,  H01S5/0078 ,  H01S5/1025 ,  H01S5/14 ,  H01S5/141 ,  H01S5/146

Abstract: An apparatus and method are provided. In particular, at least one first electro-magnetic radiation may be provided to a sample and at least one second electro-magnetic radiation can be provided to a non-reflective reference. A frequency of the first and/or second radiations varies over time. An interference is detected between at least one third radiation associated with the first radiation and at least one fourth radiation associated with the second radiation. Alternatively, the first electro-magnetic radiation and/or second electro-magnetic radiation have a spectrum which changes over time. The spectrum may contain multiple frequencies at a particular time. In addition, it is possible to detect the interference signal between the third radiation and the fourth radiation in a first polarization state. Further, it may be preferable to detect a further interference signal between the third and fourth radiations in a second polarization state which is different from the first polarization state. The first and/or second electro-magnetic radiations may have a spectrum whose mean frequency changes substantially continuously over time at a tuning speed that is greater than 100 Tera Hertz per millisecond.

公开(公告)号：US09377290B2

公开(公告)日：2016-06-28

申请号：US14256361

申请日：2014-04-18

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Seok-Hyun Yun ,  Brett Eugene Bouma ,  Guillermo J. Tearney ,  Johannes Fitzgerald De Boer

IPC: G01B9/02 ,  A61B5/00 ,  G01J3/02 ,  G01J3/453 ,  G01N21/47 ,  G02B27/48 ,  G01J9/02 ,  H01S3/08 ,  H01S3/105 ,  H01S5/14

CPC classification number: H01S5/5045 ,  A61B5/0059 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02002 ,  G01B9/02004 ,  G01B9/02043 ,  G01B9/02075 ,  G01B9/02081 ,  G01B9/02083 ,  G01B9/02084 ,  G01B9/0209 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0264 ,  G01J3/453 ,  G01J9/0215 ,  G01N21/4795 ,  G02B6/3604 ,  G02B26/12 ,  G02B27/48 ,  G02F1/093 ,  G02F1/11 ,  H01S3/0071 ,  H01S3/0078 ,  H01S3/08009 ,  H01S3/08063 ,  H01S3/105 ,  H01S3/1068 ,  H01S5/0071 ,  H01S5/0078 ,  H01S5/1025 ,  H01S5/14 ,  H01S5/141 ,  H01S5/146

Abstract: An apparatus and method are provided. In particular, a radiation can be provided which includes at least one first electro-magnetic radiation directed to a sample and at least one second electro-magnetic radiation directed to a reference, whereas a frequency of the radiation varies over time. An interference between at least one third radiation associated with the first radiation(s) and at least one fourth radiation associated with the second radiation(s) can be detected to generate an electrical first signal. A second signal associated with at least one phase of at least one frequency component of the electrical first signal can be obtained. Further, comparison data can be generated by comparing the second signal to at least one particular information.

Abstract translation: 提供了一种装置和方法。 特别地，可以提供辐射，其包括指向样品的至少一个第一电磁辐射和指向参考的至少一个第二电磁辐射，而辐射的频率随时间变化。 可以检测到与第一辐射相关联的至少一个第三辐射与与第二辐射相关联的至少一个第四辐射之间的干扰，以产生电的第一信号。 可以获得与电第一信号的至少一个频率分量的至少一个相位相关联的第二信号。 此外，可以通过将第二信号与至少一个特定信息进行比较来生成比较数据。