公开(公告)号：US20160175253A1

公开(公告)日：2016-06-23

申请号：US14910173

申请日：2014-08-06

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Henry Sun ,  Xiaohui Ma ,  Zhixin Guo ,  Sen Lin ,  Genbei Wang ,  Lulu Yan ,  Lihua Zhang ,  Shuiping Zhou ,  Shunnan Zhang

IPC: A61K9/16 ,  A61K31/365

CPC classification number: A61K9/1682 ,  A61K9/1635 ,  A61K9/1676 ,  A61K9/5026 ,  A61K9/5078 ,  A61K31/365 ,  B01J2/006

Abstract: The present invention relates to an andrographolide enteric targeting micropellet and a method for preparation thereof; furthermore, the present invention also relates to uses of andrographolide and andrographolide enteric targeting micropellets in preparation of a pharmaceutical for treatment of inflammatory bowel disease.

Abstract translation: 本发明涉及穿心莲内酯肠溶靶向微丸及其制备方法; 此外，本发明还涉及穿心莲内酯和穿心莲内酯肠溶靶向微丸在制备用于治疗炎症性肠病的药物中的用途。

公开(公告)号：US09889093B2

公开(公告)日：2018-02-13

申请号：US14910173

申请日：2014-08-06

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Henry Sun ,  Xiaohui Ma ,  Zhixin Guo ,  Sen Lin ,  Genbei Wang ,  Lulu Yan ,  Lihua Zhang ,  Shuiping Zhou ,  Shunnan Zhang

IPC: A61K9/16 ,  A61K31/365 ,  A61K9/50 ,  B01J2/00

CPC classification number: A61K9/1682 ,  A61K9/1635 ,  A61K9/1676 ,  A61K9/5026 ,  A61K9/5078 ,  A61K31/365 ,  B01J2/006

Abstract: The present invention relates to an andrographolide enteric targeting micropellet and a method for preparation thereof; furthermore, the present invention also relates to uses of andrographolide and andrographolide enteric targeting micropellets in preparation of a pharmaceutical for treatment of inflammatory bowel disease.

公开(公告)号：US20160200661A1

公开(公告)日：2016-07-14

申请号：US14914166

申请日：2014-08-26

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Shuiping Zhou ,  Wei Li ,  Yuanpeng Jin ,  Xinxin Li ,  Xiaohui Ma ,  Wei Zhou ,  Min Han ,  Shuming Li

IPC: C07C69/732 ,  C07C67/56

CPC classification number: C07C69/732 ,  A61K36/537 ,  A61K2236/00 ,  C07B2200/09 ,  C07C67/56

Abstract: The present invention relates to the medical field, specifically a salvianolic acid T as described in structural formula (I), a chiral isomer thereof, a preparation method therefor, pharmaceutical compositions, antioxidants, and free radical scavengers thereof, and a use of the compound.

Abstract translation: 本发明涉及医学领域，特别是结构式（I）所述的丹酚酸T，其手性异构体，其制备方法，药物组合物，抗氧化剂及其自由基清除剂，以及该化合物 。

公开(公告)号：US20170224622A1

公开(公告)日：2017-08-10

申请号：US15469834

申请日：2017-03-27

Applicant: TASLY PHARMACEUTICAL GROUP CO. LTD.

Inventor： Henry Sun ,  Xiaohui Ma ,  Zhixin Guo ,  Sen Lin ,  Genbei Wang ,  Lulu Yan ,  Lihua Zhang ,  Shuiping Zhou ,  Shunnan Zhang

IPC: A61K9/16 ,  A61K9/50 ,  A61K31/365

CPC classification number: A61K9/1682 ,  A61K9/1635 ,  A61K9/1676 ,  A61K9/5026 ,  A61K9/5078 ,  A61K31/365 ,  B01J2/006

Abstract: The present invention relates to an andrographolide enteric targeting micropellet and method for preparation thereof; furthermore, the present invention also relates to uses of andrographolide and andrographolide enteric targeting micropellets in the preparation of a pharmaceutical for treatment of inflammatory bowel disease.

公开(公告)号：US11491173B2

公开(公告)日：2022-11-08

申请号：US16976832

申请日：2019-04-04

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Shuiping Zhou ,  He Sun ,  Yiqian Zhang ,  Xiaohui Ma ,  Jiawen Shi ,  Yi He ,  Xinxin Li ,  Jing Wang ,  Xiaoqing Li ,  Lijun Fan ,  Jingjing Zhang

IPC: A61K31/7048 ,  A61P9/04 ,  A61K31/216 ,  A61K31/343 ,  A61K31/405 ,  A61K31/704

Abstract: Disclosed are a pharmaceutical composition and an application thereof. The pharmaceutical composition of the present invention comprises the following components in parts by weight: 2-20 parts of phenolic acids, 0.5-5 parts of flavonoids, 0.005-0.5 part of tanshinones, 5-20 parts of saponins, and 10-18 parts of volatile oils. The pharmaceutical composition has the functions of protecting against myocardial damage and treating heart failure.

公开(公告)号：US10314923B2

公开(公告)日：2019-06-11

申请号：US15541556

申请日：2015-12-24

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Jianming Chen ,  Baoan Gao ,  Qinqin Zhou ,  Shuiping Zhou ,  Nan Cai ,  Yuansheng Zhang ,  Chan Wu ,  Nong Yu ,  Lina Chen ,  Wenli Liu

IPC: A61K9/00 ,  A61K9/08 ,  A61K9/16 ,  A61K9/19 ,  A61K41/00 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/24 ,  A61K47/26 ,  A61K47/69 ,  A61K31/357

Abstract: A silybin injection contains silybin, sulfobutyl ether-β-cyclodextrin, an organic solvent for injection, a pH regulator, and may further contain a co-solvent, a lyophilization bulking agent, and water for injection.

公开(公告)号：US20170224623A1

公开(公告)日：2017-08-10

申请号：US15469711

申请日：2017-03-27

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Henry Sun ,  Xiaohui Ma ,  Zhixin Guo ,  Sen Lin ,  Genbei Wang ,  Lulu Yan ,  Lihua Zhang ,  Shuiping Zhou ,  Shunnan Zhang

IPC: A61K9/16 ,  B01J2/00 ,  A61K31/365

CPC classification number: A61K9/1682 ,  A61K9/1635 ,  A61K9/1676 ,  A61K9/5026 ,  A61K9/5078 ,  A61K31/365 ,  B01J2/006

Abstract: The present invention relates to an andrographolide enteric targeting micropellet and method for preparation thereof; furthermore, the present invention also relates to uses of andrographolide and andrographolide enteric targeting micropellets in the preparation of a pharmaceutical for treatment of inflammatory bowel disease.