公开(公告)号：US20110294117A1

公开(公告)日：2011-12-01

申请号：US12953935

申请日：2010-11-24

Applicant: Suhyeon KIM ,  Joo-won RHEE

Inventor： Suhyeon KIM ,  Joo-won RHEE

IPC: C12Q1/68 ,  G01N21/65 ,  G01N21/64 ,  G01N27/00 ,  G01N27/02

CPC classification number: B82Y15/00 ,  C12Q1/6869 ,  G01N21/552 ,  G01N21/658 ,  G01N27/44721 ,  G01N27/44726 ,  G01N27/4473 ,  G01N2021/6439 ,  Y10T436/143333 ,  C12Q2563/155 ,  C12Q2565/607

Abstract: A nucleic acid sequencing device includes at least one nanochannel, a first electrode and a second electrode disposed at opposite ends of the nanochannel for applying a voltage in the lengthwise direction of the nanochannel, and a first detector that detects a location signal of a target nucleic acid passing through the nanochannel and a second detector that detects a signal from a detectable label bound to the target nucleic acid.

Abstract translation: 核酸测序装置包括至少一个纳米通道，第一电极和第二电极，其设置在纳米通道的相对端，用于在纳米通道的长度方向上施加电压;以及第一检测器，其检测靶核酸的位置信号 通过纳米通道的酸和检测来自与靶核酸结合的可检测标记的信号的第二检测器。

公开(公告)号：US20110214991A1

公开(公告)日：2011-09-08

申请号：US13038760

申请日：2011-03-02

Applicant: Suhyeon KIM ,  Joo-won RHEE

Inventor： Suhyeon KIM ,  Joo-won RHEE

IPC: G01N27/453 ,  G01N27/447

CPC classification number: G01N33/48721

Abstract: A microfluidic device includes at least one first channel and at least one second channel or chamber which is connected to the first channel via a nanopore in a fluid communication manner, and a method of determining a nucleotide sequence of a target nucleic acid by using the same. Accordingly, the nucleotide sequence of the target nucleic acid may be efficiently determined.

Abstract translation: 微流体装置包括至少一个第一通道和至少一个第二通道或室，其以流体连通的方式通过纳米孔连接到第一通道，以及通过使用其来确定靶核酸的核苷酸序列的方法 。 因此，可以有效地确定靶核酸的核苷酸序列。

公开(公告)号：US20080311005A1

公开(公告)日：2008-12-18

申请号：US12137890

申请日：2008-06-12

Applicant: Suhyeon KIM ,  Nam HUH

Inventor： Suhyeon KIM ,  Nam HUH

IPC: G01N21/01 ,  B32B38/10 ,  B01L11/00

CPC classification number: G01N15/1404 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2200/0652 ,  B01L2300/0816 ,  G01N15/1484 ,  G01N2015/1413 ,  Y10T156/1002

Abstract: An apparatus for focusing a particle in a sheath flow, the apparatus comprising: a sheath fluid inlet for injecting a sheath fluid; a first flow channel for conveying a fluid, wherein the first flow channel extends from the sheath fluid inlet to the fluid outlet and is formed such that a channel extending from the sheath fluid inlet is divided into two subchannels that extend further and are then merged into one channel; and a second flow channel that extends from the sample fluid inlet to the sample fluid outlet, wherein the second flow channel is in fluid communication with the first flow channel at the merged channel region through the sample fluid outlet so as to introduce a particle in a sample into a sheath fluid conveyed through the first flow channel.

Abstract translation: 一种用于将颗粒聚集在鞘流中的装置，该装置包括：用于注入鞘液的鞘液入口; 用于输送流体的第一流动通道，其中所述第一流动通道从所述护套流体入口延伸到所述流体出口，并且形成为使得从所述护套流体入口延伸的通道被分成两个延伸的子通道，然后将其合并成 一个通道; 以及从所述样品流体入口延伸到所述样品流体出口的第二流动通道，其中所述第二流动通道在所述合流通道区域处通过所述样品流体出口与所述第一流动通道流体连通，以将颗粒引入到 样品进入通过第一流动通道输送的鞘液中。

公开(公告)号：US20100291558A1

公开(公告)日：2010-11-18

申请号：US12580325

申请日：2009-10-16

Applicant: Suhyeon KIM

Inventor： Suhyeon KIM

IPC: C12Q1/68 ,  C12M1/34

CPC classification number: C12Q1/6874

Abstract: Provided are magnetic particles for nucleic acid sequencing and a method of sequencing nucleic acid using the same. The nucleotide sequence of a target nucleic acid may be efficiently determined using the magnetic particles and the method of sequencing nucleic acid using the same.

Abstract translation: 提供用于核酸测序的磁性颗粒和使用其进行核酸测序的方法。 靶核酸的核苷酸序列可以使用磁性粒子和使用其进行核酸测序的方法有效地测定。