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公开(公告)号：US09136098B2
公开(公告)日：2015-09-15
申请号：US14130465
申请日：2012-07-06
Applicant: Jason Lee Wildgoose , Steven Derek Pringle , Kevil Giles , Jeffery Mark Brown , Paul Murray , Daniel James Kenny
Inventor： Jason Lee Wildgoose , Steven Derek Pringle , Kevil Giles , Jeffery Mark Brown , Paul Murray , Daniel James Kenny
CPC classification number: H01J49/10 , H01J49/0031 , H01J49/061 , H01J49/065 , H01J49/161
Abstract: A pulsed ion source is disclosed wherein the ion source is energized one or more times to generate a first group of ions and a second group of ions. The first and second groups of ions are simultaneously transmitted through an ion guide whilst keeping the first and second groups of ions isolated from each other.
Abstract translation: 公开了脉冲离子源，其中离子源被激发一次或多次以产生第一组离子和第二组离子。 第一和第二组离子同时透过离子导向器同时保持第一和第二组离子彼此隔离。
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公开(公告)号：US08952320B2
公开(公告)日：2015-02-10
申请号：US11719665
申请日：2005-11-18
Applicant: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
Inventor： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
CPC classification number: H01J49/4215 , H01J49/428
Abstract: A mass spectrometer is disclosed comprising a quadrupole rod set ion guide or mass filter device (6). A broadband frequency signal (10) having one or more notches (11a, 11b, 11c) is applied to the rods of the quadrupole rod set (6). The notched broadband frequency signal (10) causes undesired ions to be resonantly ejected from the ion guide (6). The notched broadband frequency signal (10) has frequency components missing which correspond with the resonance frequency of ions which are desired to be onwardly transmitted. The ion guide or mass filter device (6) enables a plurality of desired ions having different mass to charge ratios to be simultaneously transmitted by the ion guide or mass filter device (6) whilst other ions are resonantly ejected from the ion guide or mass filter device (6).
Abstract translation: 公开了一种质谱仪，其包括四极杆离子导向器或质量过滤装置（6）。 具有一个或多个凹口（11a，11b，11c）的宽频率信号（10）被施加到四极杆组（6）的杆上。 有缺口的宽带频率信号（10）使不想要的离子从离子导向器（6）共振地弹出。 缺口宽带频率信号（10）具有与期望向前发射的离子的谐振频率相对应的频率分量。 离子导向器或质量过滤装置（6）使得具有不同质荷比的多个所需离子能够由离子导向器或质量过滤装置（6）同时传输，而其它离子从离子导向器或质量过滤器 装置（6）。
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公开(公告)号：US20140191123A1
公开(公告)日：2014-07-10
申请号：US14130465
申请日：2012-07-06
Applicant: Jason Lee Wildgoose , Steven Derek Pringle , Kevil Giles , Jeffery Mark Brown , Paul Murray , Daniel James Kenny
Inventor： Jason Lee Wildgoose , Steven Derek Pringle , Kevil Giles , Jeffery Mark Brown , Paul Murray , Daniel James Kenny
CPC classification number: H01J49/10 , H01J49/0031 , H01J49/061 , H01J49/065 , H01J49/161
Abstract: A pulsed ion source is disclosed wherein the ion source is energised one or more times to generate a first group of ions and a second group of ions. The first and second groups of ions are simultaneously transmitted through an ion guide whilst keeping the first and second groups of ions isolated from each other.
Abstract translation: 公开了脉冲离子源，其中离子源被激发一次或多次以产生第一组离子和第二组离子。 第一和第二组离子同时透过离子导向器同时保持第一和第二组离子彼此隔离。
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公开(公告)号：US08153960B2
公开(公告)日：2012-04-10
申请号：US11916438
申请日：2006-06-05
Applicant: Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
Inventor： Kevin Giles , Martin Green , Steven Derek Pringle , Jason Lee Wildgoose
IPC: H01J49/26
CPC classification number: H01J49/427 , H01J49/4235
Abstract: An ion guide or ion trap (1) is disclosed having an entrance electrode (2) and an exit electrode (3). The potential of the exit electrode (3) is periodically dropped for a relatively short period of time allowing some ions to escape from the ion guide or ion trap (1) via an aperture in the exit electrode (3). The period of time that the potential of the exit electrode (3) is dropped for is progressively increased and ions emerge from the ion guide or ion trap (1) in a mass to charge ratio dependent manner. The ion guide or ion trap (1) may be operated as a mass separator or low resolution mass analyser.
Abstract translation: 公开了一种具有入口电极（2）和出口电极（3）的离子导向器或离子阱（1）。 出口电极（3）的电位周期性地下降相当短的时间段，允许一些离子通过出射电极（3）中的孔从离子导向器或离子阱（1）逸出。 退出电极（3）的电位下降的时间段逐渐增加，并且离子导向器或离子阱（1）以质荷比依赖的方式出现离子。 离子导向器或离子阱（1）可以作为质量分离器或低分辨率质量分析器来操作。
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公开(公告)号：US08076637B2
公开(公告)日：2011-12-13
申请号：US12524378
申请日：2008-01-25
Applicant: Steven Derek Pringle , Jason Lee Wildgoose
Inventor： Steven Derek Pringle , Jason Lee Wildgoose
CPC classification number: H01J49/428
Abstract: A mass spectrometer is disclosed comprising a quadrupole rod set ion guide or mass filter device. Broadband frequency-signals (13, 14, 15) having a plurality of frequency notches (16a; 16b; 16c) are applied sequentially to the rods of the quadrupole rod set. The notched broadband frequency signals (16a, 16b, 16c) cause undesired ions to be resonantly or parametrically ejected from the ion guide. The resulting ion signals are deconvoluted to provide a mass spectrum.
Abstract translation: 公开了一种质谱仪，其包括四极棒离子导向器或质量过滤器装置。 具有多个频率切口（16a; 16b; 16c）的宽带频率信号（13,14,15）被依次施加到四极杆组的杆上。 缺口宽带频率信号（16a，16b，16c）使离子引导不需要的离子共振或参数地喷出。 所得到的离子信号被去卷积以提供质谱。
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Patent Agency Ranking
公开(公告)号：US20090194688A1
公开(公告)日：2009-08-06
申请号：US11719665
申请日：2005-11-18
Applicant: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
Inventor： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
CPC classification number: H01J49/4215 , H01J49/428
Abstract: A mass spectrometer is disclosed comprising a quadrupole rod set ion guide or mass filter device (6). A broadband frequency signal (10) having one or more notches (11a, 11b, 11c) is applied to the rods of the quadrupole rod set (6). The notched broadband frequency signal (10) causes undesired ions to be resonantly ejected from the ion guide (6). The notched broadband frequency signal (10) has frequency components missing which correspond with the resonance frequency of ions which are desired to be onwardly transmitted. The ion guide or mass filter device (6) enables a plurality of desired ions having different mass to charge ratios to be simultaneously transmitted by the ion guide or mass filter device (6) whilst other ions are resonantly ejected from the ion guide or mass filter device (6).
Abstract translation: 公开了一种质谱仪，其包括四极杆离子导向器或质量过滤装置（6）。 具有一个或多个凹口（11a，11b，11c）的宽频率信号（10）被施加到四极杆组（6）的杆上。 有缺口的宽带频率信号（10）使不想要的离子从离子导向器（6）共振地弹出。 缺口宽带频率信号（10）具有与期望向前发射的离子的谐振频率相对应的频率分量。 离子导向器或质量过滤装置（6）使得具有不同质荷比的多个所需离子能够由离子导向器或质量过滤装置（6）同时传输，而其它离子从离子导向器或质量过滤器 装置（6）。
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公开(公告)号：US20090173877A1
公开(公告)日：2009-07-09
申请号：US12092601
申请日：2005-11-10
Applicant: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
Inventor： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
CPC classification number: H01J49/004 , G01N27/622 , H01J49/0031 , H01J49/42
Abstract: A mass spectrometer is disclosed comprising a first ion trap or ion guide (2), a single ion mobility spectrometer or separator stage (3) and a second ion trap or ion guide (4) arranged downstream of the ion mobility spectrometer or separator (3). In a mode of operation ions from the second ion trap or ion guide (4) are passed from the second ion trap or ion guide back upstream to the ion mobility spectrometer or separator (3).
Abstract translation: 公开了一种质谱仪，其包括第一离子阱或离子导向器（2），单离子迁移谱仪或分离器级（3）和设置在离子迁移谱仪或分离器（3）的下游的第二离子阱或离子导向器 ）。 在操作模式中，来自第二离子阱或离子导向器（4）的离子从第二离子阱或离子导向器返回到离子迁移谱仪或分离器（3）的上游。
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公开(公告)号：US09685313B2
公开(公告)日：2017-06-20
申请号：US12514972
申请日：2007-11-15
Applicant: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
Inventor： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
CPC classification number: H01J49/4215 , G01N27/622 , H01J49/004 , H01J49/426
Abstract: A mass spectrometer is disclosed comprising an ion mobility spectrometer and an ion gate. A collision cell is arranged downstream of the ion gate. The operation of the ion mobility spectrometer and the ion gate are synchronised so that only ions having a particular mass to charge ratio and a desired charge state are onwardly transmitted to the collision cell.
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公开(公告)号：US09673031B2
公开(公告)日：2017-06-06
申请号：US12302177
申请日：2007-06-01
Applicant: Robert Harold Bateman , Jeffery Mark Brown , Martin Green , Jason Lee Wildgoose , Anthony James Gilbert , Steven Derek Pringle
Inventor： Robert Harold Bateman , Jeffery Mark Brown , Martin Green , Jason Lee Wildgoose , Anthony James Gilbert , Steven Derek Pringle
IPC: H01J49/00
CPC classification number: H01J49/0036
Abstract: A mass spectrometer is disclosed comprising a Time of Flight mass analyzer comprising an ion detector comprising an Analog to Digital Converter. Signals from the Analog to Digital Converter are digitized and the arrival time and intensity of ions are determined. The arrival time T0 and intensity S0 of each ion arrival event is converted into two separate intensities S(n),S(n+i) which are stored in neighboring time bins T(n), T(n+1).
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公开(公告)号：US09607820B2
公开(公告)日：2017-03-28
申请号：US12306162
申请日：2007-06-25
Applicant: Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
Inventor： Robert Harold Bateman , Kevin Giles , Steven Derek Pringle , Jason Lee Wildgoose
CPC classification number: H01J49/429 , G01N27/622 , H01J49/0031 , H01J49/004
Abstract: A mass spectrometer includes an ion mobility spectrometer or separator arranged upstream of a collision or fragmentation cell. Ions are separated according to their ion mobility within the ion mobility spectrometer or separator. The kinetic energy of the ions exiting the ion mobility spectrometer or separator is increased substantially linearly with time in order to optimize the fragmentation energy of ions as they enter the collision or fragmentation cell. During the time that the potential of the ion mobility spectrometer or separator is being varied, the potential of ion-optical components upstream of the ion mobility spectrometer or separator such as an ion source, ion guide, quadrupole mass filter, optional second collision or fragmentation cell and an ion trapping device are kept constant.
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