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12 条记录 (耗时 0.013 秒)

    Modified Fibroin
    1.
    发明申请
    Modified Fibroin 审中-公开

    公开(公告)号：US20200207817A1

    公开(公告)日：2020-07-02

    申请号：US16633589

    申请日：2018-07-25

    申请人： Spiber Inc. ,  Riken

    发明人： Keisuke Morita ,  Yunosuke Abe ,  Takehisa Maekawa ,  Koichi Kotaka ,  Junichi Sugahara ,  Keiji Numata

    IPC分类号： C07K14/435 ,  D01F4/02 ,  C12N15/63

    摘要： The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)n motif-REP]m or Formula 2: [(A)n motif-REP]m-(A)n motif, in which the domain sequence has an amino acid sequence with a reduced content of a glutamine residue equivalent to an amino acid in which one or a plurality of glutamine residues in REP are deleted or substituted with other amino acid residues, as compared with a naturally occurring fibroin. [In Formula 1 and Formula 2, (A)n motif represents an amino acid sequence consisting of 4 to 27 amino acid residues, and the number of alanine residues with respect to the total number of amino acid residues in the (A)n motif is 80% or more. REP represents an amino acid sequence consisting of 10 to 200 amino acid residues. m represents an integer of 10 to 300. A plurality of (A)n motifs may be the same amino acid sequence or different amino acid sequences.]

    Method for Manufacturing Protein Fiber
    3.
    发明申请
    Method for Manufacturing Protein Fiber 有权

    公开(公告)号：US20210040648A1

    公开(公告)日：2021-02-11

    申请号：US16965626

    申请日：2019-01-31

    申请人： Spiber Inc.

    发明人： Yunosuke Abe ,  Hirotada Ando

    IPC分类号： D01F4/02 ,  D01D5/06

    摘要： The present invention relates to a method for manufacturing a protein fiber, the method including a step of bringing a spinning raw liquid containing a spider silk protein and a solvent into contact with a coagulation liquid to coagulate the spider silk protein, in which the coagulation liquid contains a ketone.

    Modified Fibroin Fibers
    4.
    发明申请
    Modified Fibroin Fibers 有权

    公开(公告)号：US20220074077A1

    公开(公告)日：2022-03-10

    申请号：US17279081

    申请日：2019-09-27

    申请人： Spiber Inc.

    发明人： Yunosuke Abe ,  Masato Matsuo ,  Shota Togashi

    IPC分类号： D01F4/02 ,  D01D11/00

    摘要： The present invention provides a modified fibroin fiber having a shrinkage history of being irreversibly shrunk after spinning, the modified fibroin fiber containing modified fibroin, wherein a fiber diameter of a raw material fiber before being irreversibly shrunk exceeds 25 μm.

    Protein Fiber Production Method
    5.
    发明申请
    Protein Fiber Production Method 有权

    公开(公告)号：US20210395317A1

    公开(公告)日：2021-12-23

    申请号：US17279564

    申请日：2019-09-30

    申请人： Spiber Inc.

    发明人： Yunosuke Abe ,  Hirotada Ando ,  Koichi Kotaka

    IPC分类号： C07K14/435 ,  C07K14/47 ,  D01D5/06 ,  D01F4/00 ,  D01F4/02

    摘要： Disclosed is a method for producing a protein fiber, the method including: bringing a spinning dope containing a protein and an organic solvent into contact with a coagulation liquid to coagulate the protein, wherein a content of the protein in the spinning dope is more than 10% by mass based on a total amount of the spinning dope, and the coagulation liquid contains water or an aqueous solution of pH 0.25 or more and pH 10.00 or less.

    Method for Manufacturing Protein Molded Body
    7.
    发明申请
    Method for Manufacturing Protein Molded Body 有权

    公开(公告)号：US20220324923A1

    公开(公告)日：2022-10-13

    申请号：US17764669

    申请日：2020-09-28

    申请人： Spiber Inc.

    发明人： Kentaro Takahashi ,  Atsushi Ikeda ,  Hideki Kagata ,  Yunosuke Abe ,  Kazuki Sakata

    IPC分类号： C07K14/435 ,  D01F4/02

    摘要： An object of the present invention is to provide a method for advantageously producing a protein molded article which can solve a problem caused by esterification of a hydroxyl group contained in a protein while maintaining a sufficient strength. A method for producing a protein molded article according to the present invention includes a step of bringing a raw material molded article containing a protein in which a hydroxyl group is esterified into contact with an acidic or basic medium in a state of applying a tensile force, thus hydrolyzing an ester group.

    Method for Manufacturing Artificially-Structured Protein Fiber
    8.
    发明申请
    Method for Manufacturing Artificially-Structured Protein Fiber 有权

    公开(公告)号：US20220127755A1

    公开(公告)日：2022-04-28

    申请号：US17428136

    申请日：2020-02-07

    申请人： Spiber Inc.

    发明人： Hirotada Ando ,  Hideto Ishii ,  Koichi Kotaka ,  Ryoko Sato ,  Hiroshi Kano ,  Jun Kobayashi ,  Akito Sato ,  Yunosuke Abe

    IPC分类号： D01D5/06 ,  C07K14/435 ,  D01F4/02

    摘要： An object of the present invention is to provide a method for producing an artificial structural protein fiber having a small diameter and having a stress equal to or higher than that of the related art. A method for producing an artificial structural protein fiber according to the present invention is a method for producing an artificial structural protein fiber by a wet spinning method, the method including a coagulation step of discharging a spinning dope containing an artificial structural protein and an organic solvent from a spinneret into a coagulation liquid to coagulate the artificial structural protein, wherein a bath draft in the coagulation step is more than 0.4 and 20 or less.