IMAGE-GUIDED DELIVERY OF A MIXTURE OF BACTERIA AND NON-BACTERIA LINKED NANOPARTICLES

    公开(公告)号:US20180289626A1

    公开(公告)日:2018-10-11

    申请号:US16005982

    申请日:2018-06-12

    摘要: A computer-implemented method for image-guided delivery of a nanoparticle mixture to a target tumor located in a region of interest includes selecting a non-hypoxic delivery location within the region of interest for delivery of a non-bacteria-associated nanoparticle component included in the nanoparticle mixture and selecting a hypoxic delivery location within the region of interest for delivery of a bacteria-associated nanoparticle component included in the nanoparticle mixture. An image-guided delivery and monitoring process may then be performed. During this process intra-operative images of the region of interest are continually acquired and used to guide placement of a device into the non-hypoxic delivery location, monitor delivery of the non-bacteria-associated nanoparticle component included in the nanoparticle mixture at the non-hypoxic delivery location, guide placement of the device into the hypoxic delivery location, and monitor delivery of the bacteria-associated nanoparticle component included in the nanoparticle mixture at the hypoxic delivery location.

    Image-guided delivery of a mixture of bacteria and non-bacteria linked nanoparticles

    公开(公告)号:US10022333B2

    公开(公告)日:2018-07-17

    申请号:US15178588

    申请日:2016-06-10

    摘要: A computer-implemented method for image-guided delivery of a nanoparticle mixture to a target tumor located in a region of interest includes selecting a non-hypoxic delivery location within the region of interest for delivery of a non-bacteria-associated nanoparticle component included in the nanoparticle mixture and selecting a hypoxic delivery location within the region of interest for delivery of a bacteria-associated nanoparticle component included in the nanoparticle mixture. An image-guided delivery and monitoring process may then be performed. During this process intra-operative images of the region of interest are continually acquired and used to guide placement of a device into the non-hypoxic delivery location, monitor delivery of the non-bacteria-associated nanoparticle component included in the nanoparticle mixture at the non-hypoxic delivery location, guide placement of the device into the hypoxic delivery location, and monitor delivery of the bacteria-associated nanoparticle component included in the nanoparticle mixture at the hypoxic delivery location.

    VIRTUAL BIOPSY TECHNIQUES FOR ANALYZING DISEASES
    4.
    发明申请
    VIRTUAL BIOPSY TECHNIQUES FOR ANALYZING DISEASES 审中-公开
    用于分析疾病的虚拟生物技术

    公开(公告)号:US20170032090A1

    公开(公告)日:2017-02-02

    申请号:US15223927

    申请日:2016-07-29

    IPC分类号: G06F19/00 G06N7/00

    摘要: A computer-implemented method for deriving biopsy results in a non-invasive manner includes acquiring a plurality of training data items. Each training data item comprises non-invasive patient data and one or more biopsy derived scores associated with an individual. The method further includes extracting a plurality of features from the non-invasive patient data based on the one or more biopsy derived scores and training a predictive model to generate a predicted biopsy score based on the plurality of features and the one or more biopsy derived scores.

    摘要翻译: 用于导出活组织检查的计算机实现的方法导致非侵入性方式包括获取多个训练数据项。 每个训练数据项包括非侵入性患者数据和与个体相关联的一个或多个活组织检验得出的得分。 所述方法还包括基于所述一个或多个活组织检查得出的分数从所述非侵入性患者数据中提取多个特征,并且训练预测模型以基于所述多个特征和所述一个或多个活组织检查得出得分来产生预测的活检得分 。

    Image-guided delivery of a mixture of bacteria and non-bacteria linked nanoparticles

    公开(公告)号:US10471018B2

    公开(公告)日:2019-11-12

    申请号:US16005982

    申请日:2018-06-12

    摘要: A computer-implemented method for image-guided delivery of a nanoparticle mixture to a target tumor located in a region of interest includes selecting a non-hypoxic delivery location within the region of interest for delivery of a non-bacteria-associated nanoparticle component included in the nanoparticle mixture and selecting a hypoxic delivery location within the region of interest for delivery of a bacteria-associated nanoparticle component included in the nanoparticle mixture. An image-guided delivery and monitoring process may then be performed. During this process intra-operative images of the region of interest are continually acquired and used to guide placement of a device into the non-hypoxic delivery location, monitor delivery of the non-bacteria-associated nanoparticle component included in the nanoparticle mixture at the non-hypoxic delivery location, guide placement of the device into the hypoxic delivery location, and monitor delivery of the bacteria-associated nanoparticle component included in the nanoparticle mixture at the hypoxic delivery location.