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1.发明申请SAMPLE COOLING DEVICE, AUTOSAMPLER PROVIDED WITH THE SAME, AND SAMPLE COOLING METHOD 有权样品冷却装置，自动保护装置，以及样品冷却方法公开(公告)号：US20150355061A1
公开(公告)日：2015-12-10
申请号：US14759105
申请日：2013-03-18
Applicant: SHIMADZU CORPORATION
Inventor： Takashi INOUE
CPC classification number: G01N1/42 , B01L7/00 , B01L2300/0663 , B01L2300/10 , B01L2300/1894 , F25B47/006 , F25D21/04 , G01N30/24 , G01N35/1095 , G01N2035/00445
Abstract: There are provided a sample cooling device capable of effectively removing moisture in the air inside an accommodating chamber where a sample container is accommodated, and of preventing a problem caused by occurrence of frost, an autosampler provided with the same, and a sample cooling method. A first driving process of setting a set temperature of a dehumidifier section to at or below the freezing point, and a second driving process of stopping driving of the dehumidifier section or of raising the set temperature of the dehumidifier section to above the freezing point after the first driving process is performed over a predetermined period of time are performed. Thus, the set temperature of the dehumidifier section may be made to at or below the freezing point by the first driving process, and moisture in the air inside the accommodating chamber may be made to temporarily attach to the dehumidifier section as frost and then be melted by the second driving process and be collected as water.
Abstract translation: 提供一种样品冷却装置，其能够有效地除去容纳样本容器的容纳室内的空气中的水分，并且防止由霜冻发生引起的问题，具有该问题的自动进样器和样品冷却方法。 将除湿部的设定温度设定在冰点以下或冰点以下的第一驱动处理，以及停止除湿部的驱动或将除湿部的设定温度提高到冰点以上的第二驱动处理 执行在预定时间段内的第一驱动处理。 因此，可以通过第一驱动处理使除湿部的设定温度成为冰点或低于冰点，并且容纳室内的空气中的水分可以作为霜临时附接到除湿器部分，然后熔化 通过第二个驾驶过程，并作为水收集。
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公开(公告)号：US20220259542A1
公开(公告)日：2022-08-18
申请号：US17628528
申请日：2019-07-26
Applicant: SHIMADZU CORPORATION
Inventor： Yamato MAEDA , Akari TAKEDA , Yoshitake YAMAMOTO , Yoshitaka NODA , Takashi INOUE
Abstract: A cell collecting device include a pipette tip that sucks substances in a cell culture container, a first valve connected to the pipette tip through a first flow path, a first pump connected to the first valve through a second flow path, and a second pump connected to the first valve through a third flow path. In a remove mode, the first valve is switched to connect the first flow path and the second flow path to each other and disconnect the third flow path, and the first pump is driven to discharge waste in the cell culture container, that has been sucked from the pipette tip, from a drain of the first pump through the first flow path and the second flow path, and in a picking mode, the first valve is switched to connect the first flow path and the third flow path to each other and disconnect the second flow path, and the second pump is driven to suck cells in the cell culture container using the pipette tip.
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公开(公告)号：US20220026400A1
公开(公告)日：2022-01-27
申请号：US17295979
申请日：2018-12-10
Applicant: SHIMADZU CORPORATION
Inventor： Shotaro ANDO , Takashi INOUE , Kenichi YASUNAGA
Abstract: The auto-sampler for chromatographs includes a sampling needle, a pipe, a pump portion, and a connecting mechanism configured to connect the sampling needle and the pipe. The connecting mechanism includes a first component fixed to the sampling needle, a second component fixed to the pipe, a fixing component, and a packing. The fixing component fixes the first component and the second component using screwing of screws while the end surface of the sampling needle and the end surface of the pipe are in contact with the packing. As a result, dead volume at the connecting portion between the sampling needle and the pipe is reduced.
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公开(公告)号：US20210285919A1
公开(公告)日：2021-09-16
申请号：US17125050
申请日：2020-12-17
Applicant: SHIMADZU CORPORATION
Inventor： Satoru WATANABE , Takashi INOUE
Abstract: An autosampler includes a retention path for injecting a sample into a mobile phase that flows through an analysis path to a column, the retention path including a needle at a downstream end and holding the sample, an injection path including a port at an upstream end for injecting into the analysis path, the sample injected from the needle into the port, a low-pressure path having an upstream end connected to a pump, and a valve that can switch between a first state in which an upstream analysis path and a downstream analysis path are connected and a downstream end of the low-pressure path and an upstream end of the retention path are connected and a second state in which the upstream analysis path and the upstream end of the retention path are connected and the downstream end of the injection path and the downstream analysis path are connected.
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公开(公告)号：US20200377833A1
公开(公告)日：2020-12-03
申请号：US16969859
申请日：2018-03-16
Applicant: SHIMADZU CORPORATION
Inventor： Takashi INOUE , Kenji TAKAKURA , Yoshitaka NODA , Yasuaki MATSUNAGA , Mika OKADA , Akari TAKEDA
Abstract: A cell picking device includes a sucker having a pipette tip attached to a tip portion of the sucker and is used to suck the cell from a tip of the pipette tip, a driver configured to cause the sucker to perform a suction operation and move the sucker in a horizontal-plane direction and an axial direction of the pipette tip with the sucker inclined with respect to a vertical direction. A controller moves the sucker such that the tip of the pipette tip moves in a horizontal direction while being in contact with a bottom surface of the container installed on the sample mounting stage in a predetermined position on the sample mounting stage to desorb a cell arranged in the predetermined position from the bottom surface of the container, and suck the cell desorbed from the bottom surface of the container from the tip of the pipette tip.
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Patent Agency Ranking
公开(公告)号：US20200241030A1
公开(公告)日：2020-07-30
申请号：US16649099
申请日：2018-06-20
Applicant: Shimadzu Corporation
Inventor： Hiroyuki MINATO , Takashi INOUE
Abstract: The sample plate has a principal plane in which a plurality of wells is arranged. The sample plate has a plurality of through-holes each allowing a sampling needle to pass through in a region of the principal plane where the wells are not provided, and positions of the wells and positions of the through-holes are designed such that when two pieces of the sample plates are arranged up and down with a predetermined positional relationship in a state in which respective principal planes are arranged in parallel each other, the through-holes of the sample plate arranged on an upper side is arranged at positions directly above respective wells of the sample plate arranged on a lower side.
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公开(公告)号：US20220260605A1
公开(公告)日：2022-08-18
申请号：US17628029
申请日：2019-07-26
Applicant: SHIMADZU CORPORATION
Inventor： Mika OKADA , Akari TAKEDA , Yamato MAEDA , Yoshitake YAMAMOTO , Potsun CHiANG , Yoshitaka NODA , Takashi INOUE
Abstract: A cell picking device includes a stage, a sucker, a driver, a work content receiver, a registrar and a device controller. A sample container is placed on the stage. The driver is provided to execute sample scraping work and sample sucking work using a pipette tip attached to the sucker. In a case in which selection of work contents of the driver is received by the work content receiver, a work procedure including the received work contents of the driver is registered by the registrar. The work of the driver is controlled by the device controller in accordance with the registered work procedure.
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公开(公告)号：US20210148869A1
公开(公告)日：2021-05-20
申请号：US17047022
申请日：2019-01-16
Applicant: SHIMADZU CORPORATION
Inventor： Yusuke YOKOI , Takaaki FUJITA , Takashi INOUE , Kenichi YASUNAGA
Abstract: An autosampler is switched selectively between an injecting mode where a sampling flow path is incorporated into an analysis flow path of a liquid chromatograph and a loading mode where the sampling flow path is not incorporated into the analysis flow path and injects a sample into the analysis flow path at a position farther upstream than a separation column by being switched to the injecting mode with the sample held in the sampling flow path, and includes a clog determiner configured to acquire a sending liquid pressure of a liquid sending pump that sends a mobile phase in the analysis flow path, obtain a variation value of the liquid sending pressure when the injecting mode and the loading mode are switched and determine presence or absence of a clog in a system incorporated into the analysis flow path in the injecting mode based on the obtained variation value.
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公开(公告)号：US20210060568A1
公开(公告)日：2021-03-04
申请号：US16958679
申请日：2018-08-22
Applicant: SHIMADZU CORPORATION
Inventor： Takashi INOUE
Abstract: A vial holder includes a thermally conductive holder positioned at a lower part and a non-thermally conductive holder positioned at an upper part. The thermally conductive holder is made of thermally conductive material and supports at least bottom surfaces of the vials accommodated in the accommodation holes. The non-thermally conductive holder is made of non-thermally conductive material, is arranged so as to cover an upper surface of the thermally conductive holder while being in contact with the upper surface, and includes a plurality of through holes constituting at least a part of the accommodation holes.
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公开(公告)号：US20190383777A1
公开(公告)日：2019-12-19
申请号：US16010966
申请日：2018-06-18
Applicant: Shimadzu Corporation
Inventor： Takashi INOUE
Abstract: A first mixer mixes solvents therein. A second mixer has a capacity different from that of the first mixer, and mixes solvents therein. A first separation column is associated with the first mixer. A second separation column is associated with the second mixer. A first valve enables switchover between a first communication state in which the first mixer and the first separation column communicate with a detector, and a second communication state in which the second mixer and the second separation column communicate with the detector. Only by switching the first valve, it is possible to switch between the first communication state and the second communication state. The internal capacity of a flow channel in the first communication state differs from that in the second communication state. Therefore, it is easy to perform analysis with different internal capacities.
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