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公开(公告)号：US12083151B2
公开(公告)日：2024-09-10
申请号：US17938184
申请日：2022-10-05
发明人： Matthew R. Henn , Geoffrey von Maltzahn , Anthony Mario D'Onofrio , Kevin Daniel Litcofsky , David Arthur Berry , David N. Cook , Noubar B. Afeyan , John Grant Aunins
IPC分类号： A61K39/02 , A23L33/10 , A23L33/135 , A23P10/30 , A61K9/00 , A61K9/48 , A61K35/74 , A61K35/742 , A61K38/13 , A61K39/08 , A61K45/06
CPC分类号： A61K35/742 , A23L33/127 , A23L33/135 , A23P10/30 , A61K9/0053 , A61K9/4891 , A61K35/74 , A61K38/13 , A61K45/06 , A23V2002/00 , Y02A50/30
摘要： Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
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公开(公告)号：US11666612B2
公开(公告)日：2023-06-06
申请号：US17140385
申请日：2021-01-04
发明人： Matthew R. Henn , David N. Cook , Toshiro K. Ohsumi , Mary-Jane Lombardo McKenzie , Kevin D. Litcofsky , Han Zhang , John Grant Aunins , David Arthur Berry
IPC分类号： A61K35/742 , A61K35/74 , A61K35/741 , A61K35/745
CPC分类号： A61K35/742 , A61K35/74 , A61K35/741 , A61K35/745
摘要： Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
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公开(公告)号：US11458173B2
公开(公告)日：2022-10-04
申请号：US17120657
申请日：2020-12-14
发明人： Matthew R. Henn , Geoffrey von Maltzahn , Anthony Mario D'Onofrio , Kevin Daniel Litcofsky , David Arthur Berry , David N. Cook , Noubar B. Afeyan , John Grant Aunins
IPC分类号： A61K39/02 , A61K35/742 , A61K35/74 , A23L33/10 , A23L33/135 , A61K38/13 , A23P10/30 , A61K9/00 , A61K9/48 , A61K45/06
摘要： Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
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公开(公告)号：US11266699B2
公开(公告)日：2022-03-08
申请号：US16230807
申请日：2018-12-21
发明人： Matthew R. Henn , Kevin Daniel Litcofsky , Anthony Mario D'Onofrio , Toshiro K. Ohsumi , Mary-Jane Lombardo McKenzie , Geoffrey von Maltzahn , David N. Cook , David Arthur Berry , Noubar B. Afeyan , John Grant Aunins
IPC分类号： A61K38/13 , A61K35/742 , A61K35/74 , C12N1/20 , A23L33/135 , A61K45/06 , A61K35/00
摘要： Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
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公开(公告)号：US10881696B2
公开(公告)日：2021-01-05
申请号：US15990539
申请日：2018-05-25
发明人： Matthew R. Henn , David N. Cook , Toshiro K. Ohsumi , Mary-Jane Lombardo McKenzie , Kevin D. Litcofsky , Han Zhang , John Grant Aunins , David Arthur Berry
IPC分类号： A61K35/742 , A61K35/74 , A61K35/741 , A61K35/745
摘要： Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
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公开(公告)号：US20200345792A1
公开(公告)日：2020-11-05
申请号：US16230807
申请日：2018-12-21
发明人： Matthew R. Henn , Kevin Daniel Litcofsky , Anthony Mario D'Onofrio , Toshiro K. Ohsumi , Mary-Jane Lombardo McKenzie , Geoffrey von Maltzahn , David N. Cook , David Arthur Berry , Noubar B. Afeyan , John Grant Aunins
IPC分类号： A61K35/742 , A61K35/74 , C12N1/20 , A23L33/135 , A61K45/06
摘要： Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
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公开(公告)号：US11458174B2
公开(公告)日：2022-10-04
申请号：US17120666
申请日：2020-12-14
发明人： Matthew R. Henn , Geoffrey von Maltzahn , Anthony Mario D'Onofrio , Kevin Daniel Litcofsky , David Arthur Berry , David N. Cook , Noubar B. Afeyan , John Grant Aunins
IPC分类号： A61K39/02 , A61K35/742 , A61K35/74 , A23L33/10 , A23L33/135 , A61K38/13 , A23P10/30 , A61K9/00 , A61K9/48 , A61K45/06
摘要： Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
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8.发明授权公开(公告)号：US09956282B2
公开(公告)日：2018-05-01
申请号：US15104873
申请日：2014-12-16
发明人： David N. Cook , David Arthur Berry , Geoffrey von Maltzahn , Matthew R. Henn , Han Zhang , Brian Goodman
IPC分类号： A61K39/35 , A23L33/135 , A61K35/742 , A61K45/06 , A61K49/00 , G01N33/68 , A61K39/00 , A61K35/00
CPC分类号： A61K39/35 , A23L33/135 , A23V2002/00 , A61K35/742 , A61K39/02 , A61K45/06 , A61K49/0004 , A61K2035/115 , A61K2039/52 , A61K2039/54 , A61K2039/545 , A61K2039/55544 , A61K2039/577 , A61K2039/58 , G01N33/6863 , G01N2333/52 , Y02A50/469
摘要： Provided are compositions containing combinations of bacteria useful for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract, or other niche of a mammalian subject, and methods for use thereof, in particular for the treatment, inhibition, or prevention of immune disorders such as allergies and asthma.
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公开(公告)号：US09585921B2
公开(公告)日：2017-03-07
申请号：US14884655
申请日：2015-10-15
发明人： Gregory McKenzie , Mary-Jane Lombardo McKenzie , David N. Cook , Marin Vulic , Geoffrey von Maltzahn , Brian Goodman , John Grant Aunins , Matthew R. Henn , David Arthur Berry , Jonathan Winkler
IPC分类号： C12N3/00 , A61K35/741 , A61K9/00 , A61K45/06 , A61K35/74 , C12N1/20 , A61K35/742 , A61K35/744 , A61K35/745 , A61K35/747 , A61K9/48
CPC分类号： A61K35/741 , A61K9/0053 , A61K9/48 , A61K9/4816 , A61K35/37 , A61K35/74 , A61K35/742 , A61K35/744 , A61K35/745 , A61K35/747 , A61K45/06 , C12N1/20 , Y02A50/402 , Y02A50/469 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/48 , Y02A50/481
摘要： Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
摘要翻译： 本文公开了含有非致病性，发芽能力的细菌孢子，用于预防，控制和治疗胃肠疾病，病症和病症以及一般营养健康的治疗组合物。
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10.发明申请Bacterial Compositions and Methods of Use Thereof for Treatment of Immune System Disorders 有权细菌组合物及其使用方法用于治疗免疫系统疾病公开(公告)号：US20160317653A1
公开(公告)日：2016-11-03
申请号：US15104873
申请日：2014-12-16
发明人： David N. Cook , David Arthur Berry , Geoffrey von Maltzahn , Matthew R. Henn , Han Zhang , Brian Goodman
IPC分类号： A61K39/35 , A23L33/135 , A61K49/00 , G01N33/68 , A61K35/742 , A61K45/06
CPC分类号： A61K39/35 , A23L33/135 , A23V2002/00 , A61K35/742 , A61K39/02 , A61K45/06 , A61K49/0004 , A61K2035/115 , A61K2039/52 , A61K2039/54 , A61K2039/545 , A61K2039/55544 , A61K2039/577 , A61K2039/58 , G01N33/6863 , G01N2333/52 , Y02A50/469
摘要： Provided are compositions containing combinations of bacteria useful for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract, or other niche of a mammalian subject, and methods for use thereof, in particular for the treatment, inhibition, or prevention of immune disorders such as allergies and asthma.
摘要翻译： 提供了含有用于维持或恢复胃肠道或哺乳动物受试者的其他小生境中的健康微生物群的细菌组合的组合物及其使用方法，特别是用于治疗，抑制或预防免疫疾病，例如 作为过敏和哮喘。
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