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公开(公告)号：US20190134313A1
公开(公告)日：2019-05-09
申请号：US16312476
申请日：2017-06-30
摘要： A drug delivery device comprises a medicament reservoir attached to a housing, a drive mechanism comprising a plunger movable relative to the housing, a dose selecting element releasably coupled to the drive mechanism and rotatable relative to the housing, a trigger axially movable relative to the housing, and a limiter selectively permitting and preventing axial movement of the trigger depending on the amount of a selected dose. The limiter is constrained to the dose selecting element and to the trigger. One of the limiter or a component part is axially coupled to the housing comprises a track which is in engagement with a blocking feature of the other of the limiter or the component part axially coupled to the housing. The track comprises a narrow section limiting relative movement between the track and the blocking feature and a wide section permitting relative movement between the track and the blocking feature.
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公开(公告)号：US20240115810A1
公开(公告)日：2024-04-11
申请号：US18540467
申请日：2023-12-14
申请人： Sanofi
发明人： Michael Schabbach , Anthony Paul Morris , Ronald Antony Smith , Brian Charles Molyneux , Paul Richard Draper , Craig Ashley Mason , Oliver Charles Gazeley , Daniel Edward Clark , David Aubrey Plumptre , Aidan Michael O'Hare , Richard James Thomas , Felix Kramer , Beat Wyss , Philipp Müller
CPC分类号： A61M5/3155 , A61M5/31551 , A61M5/3202 , A61M2005/3126
摘要： The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.
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公开(公告)号：US11642468B2
公开(公告)日：2023-05-09
申请号：US16766144
申请日：2018-11-23
申请人： SANOFI
发明人： Michael Schabbach , Anthony Paul Morris , Ronald Antony Smith , Brian Charles Molyneux , Paul Richard Draper , Craig Ashley Mason , Oliver Charles Gazeley , Daniel Edward Clark , David Aubrey Plumptre , Aidan Michael O'Hare , Richard James Thomas , Felix Kramer , Beat Wyss , Philipp Muller
CPC分类号： A61M5/3155 , A61M5/31551 , A61M5/3202 , A61M2005/3126 , A61M2205/3306 , A61M2205/3584 , A61M2205/52 , A61M2205/581 , A61M2205/8212
摘要： The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.
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公开(公告)号：US20230036681A1
公开(公告)日：2023-02-02
申请号：US17787066
申请日：2020-12-16
申请人： Sanofi
发明人： David Aubrey Plumptre , Robert Veasey , Paul Roger Griffin , Rory James Livingston Hawkins , Charles Henry Bertinat
摘要： The disclosure relates to a cartridge assembly for a drug delivery device, the cartridge assembly comprising a cartridge containing a drug; a cartridge holder, the cartridge holder defining an interior cartridge holding section, where the cartridge is arranged within the cartridge holding section, wherein the cartridge holder comprises a distal region with a needle connector arranged at a distal end of the distal region and a main body region; a fixing feature which is arranged at the distal region; and a region with reduced mechanical stiffness compared to the stiffness of the main body region, the region with reduced mechanical stiffness being integrated into the distal region and arranged between the needle connector and the fixing feature, such that when the cartridge is moved in a proximal direction, an emerging load is transferred from the cartridge to the fixing feature and to the main body region in the proximal direction.
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公开(公告)号：US11406762B2
公开(公告)日：2022-08-09
申请号：US16312204
申请日：2017-06-30
申请人： SANOFI
发明人： Markus Ploch , Aled Meredydd James , Anthony Paul Morris , Matthew Meredith Jones , Oliver Charles Gazeley , Robert Veasey , David Aubrey Plumptre
摘要： A drug delivery device comprising a housing body; a piston rod configured to rotate in a rotational direction during dose dispensing under a driving force; and a threaded insert, wherein the piston rod is in threaded engagement with the threaded insert such that during the dose dispensing. the piston rod displaces axially in a distal direction relative to the threaded insert for displacement of a cartridge hung. The threaded insert is movable relative to a stop provided in the housing body and a spring is provided to bias the threaded insert against the stop so that the rotation of the piston rod causes the threaded insert to move away from the stop in response to reaction forces, induced by the cartridge bung into the threaded insert, acting on the piston rod in a proximal direction when the reaction forces exceed a biasing force of the spring.
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公开(公告)号：US20220241514A1
公开(公告)日：2022-08-04
申请号：US17728165
申请日：2022-04-25
IPC分类号： A61M5/315
摘要： A supplemental device for attachment to an injection device, the supplemental device having a housing containing at least two electromechanical switches each having an open state and a closed state and a protrusion associated with each switch configured to protrude from the housing so as to contact a rotatable surface of the injection device while the supplemental device is attached to the injection device; and a processor arrangement configured to detect a change in the state of each of the switches; and to determine a direction of rotation of the rotatable surface of the injection device from the detected state changes.
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公开(公告)号：US11020533B2
公开(公告)日：2021-06-01
申请号：US16555772
申请日：2019-08-29
发明人： Frank Erbstein , Paul Richard Draper , Robert Frederick Veasey , David Aubrey Plumptre , Joseph Butler
摘要： A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the medicament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.
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公开(公告)号：US11013863B2
公开(公告)日：2021-05-25
申请号：US16126763
申请日：2018-09-10
发明人： David Aubrey Plumptre , Paul Richard Draper , David Richard Mercer , Naceur Rekaya , Paul Griffin
摘要： The present disclosure pertains to an assembly for a drug delivery device having a housing part, a piston rod displaceable relative to the housing part, a first sleeve member and a second sleeve member. First and second sleeve members are coupled to the housing part. In an initial state of the assembly the first sleeve member is movable from an initial position to a second position relative to the second sleeve member which allows the piston rod to axially travel from an initial position to a predetermined second position such that the assembly is in a primed state. Moreover, in the primed state of the assembly, with the first sleeve member being in the second position relative to the second sleeve member, first and second sleeve members are permanently rotationally and axially locked to each other by a first engagement feature such that first and second sleeve members together form a sleeve.
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公开(公告)号：US10821231B2
公开(公告)日：2020-11-03
申请号：US16385682
申请日：2019-04-16
摘要： The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.
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公开(公告)号：US10729855B2
公开(公告)日：2020-08-04
申请号：US15787737
申请日：2017-10-19
摘要： A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
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