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1.Pharmaceutical compositions of quinine polygalacturonate and methods for their use 失效
Title translation: 聚对苯二甲酸乙二醇酯的药物组合物及其使用方法公开(公告)号:US3538218A
公开(公告)日:1970-11-03
申请号:US3538218D
申请日:1968-12-30
Applicant: SYNERGISTICS INC
Inventor: SACKLER MORTIMER D , HALPERN ALFRED
IPC: A61K31/49 , A61K31/715 , C07D453/04 , A61K27/00
CPC classification number: A61K31/715 , A61K31/49 , C07D453/04 , Y10S514/895
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公开(公告)号:US3360535A
公开(公告)日:1967-12-26
申请号:US38434064
申请日:1964-07-22
Applicant: GRAY PHARMACEUTICAL CO , SYNERGISTICS INC
Inventor: ALFRED HALPERN , SACKLER MORTIMER D , SACKLER RAYMOND R
CPC classification number: C07C65/105 , Y10S514/863 , Y10S514/932 , Y10S514/933
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3.Certain quaternary ammonium and pyridinium salicylates,acetylsalicylates,para-aminosalicylates and undecylenates 失效
Title translation: 某些季铵盐和磷酸吡啶盐酸盐,乙酰乙酸盐,对氨基苯甲酸盐和未处理剂公开(公告)号:US3498991A
公开(公告)日:1970-03-03
申请号:US3498991D
申请日:1966-03-15
Applicant: SYNERGISTICS INC
Inventor: HALPERN ALFRED , SACKLER MORTIMER D , SACKLER RAYMOND R
IPC: C07D211/14 , C07D213/20 , C07D307/52 , C07D333/20 , C07D31/34 , C07D29/24
CPC classification number: C07D333/20 , C07D211/14 , C07D213/20 , C07D307/52
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公开(公告)号:US3452022A
公开(公告)日:1969-06-24
申请号:US3452022D
申请日:1966-08-08
Applicant: SYNERGISTICS INC
Inventor: SACKLER MORTIMER D , HALPERN ALFRED
IPC: A61K31/49 , A61K31/715 , C07D453/04 , C07D33/14 , A61K27/00 , C07D43/24
CPC classification number: A61K31/715 , A61K31/49 , C07D453/04 , Y10S514/937 , Y10S514/951 , Y10S514/96 , Y10S514/962
Abstract: Novel quinine polygalacturonate is prepared by either reacting quinine with polygalacturonic acid until the pH of the mixture is 6-7.5 or reacting an aqueous solution of a quinine salt with an aqueous solution of an alkali or alkaline earth metal salt of polygalacturonic acid until the pH of the solution is 6-7.5. Pharmaceutical compositions comprise quinine polygalacturonate in conjunction with a diluent and may be administered orally or parenterally. They are effective in treatment of malaria.
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5.Sennoside derivatives and pharmaceutical compositions containing same 失效
Title translation: 番泻苷衍生物和含有它们的药物组合物公开(公告)号:US3274053A
公开(公告)日:1966-09-20
申请号:US19960562
申请日:1962-06-04
Applicant: SYNERGISTICS INC
Inventor: ALFRED HALPERN , SACKLER MORTIMER D
IPC: A61K36/482 , C07H15/244 , C07H15/256
CPC classification number: C07H15/256 , A61K36/482 , C07H15/244
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