公开(公告)号：US20210013022A1

公开(公告)日：2021-01-14

申请号：US16881131

申请日：2020-05-22

Applicant: SHIMADZU CORPORATION

Inventor： Yusuke Tateishi

IPC: H01J49/42 ,  G01N30/72 ,  H01J49/00 ,  H01J49/40 ,  H01J49/02

Abstract: Provided is a mass spectrometer which repeats the operation of capturing ions originating from a sample component into an ion trap (22), ejecting the ions from the ion trap, and analyzing the ions with a TOF mass analyzer (23). A capturing voltage generator (51) applies an ion-capturing radio-frequency voltage to the ion trap. An ejecting voltage generator (52) applies an ion-ejecting voltage whose phase is synchronized with the radio-frequency voltage. A controller (4) controls those devices to introduce next ions to be analyzed into the ion trap while performing a mass spectrometric analysis in the TOF mass analyzer. A blank signal acquirer (4, 32) acquires a blank signal within a measurement period or measurement window while the ion trap is being operated. A noise remover (33) subtracts blank-signal data from signal intensity data acquired by a sample measurement. A spectrum creator (34) creates a mass spectrum based on noise-removed data.

公开(公告)号：US11587780B2

公开(公告)日：2023-02-21

申请号：US17466565

申请日：2021-09-03

Applicant: SHIMADZU CORPORATION

Inventor： Yusuke Tateishi ,  Hiroyuki Miura ,  Hideaki Izumi

IPC: H01J49/40 ,  H01J49/06

Abstract: Provided is a time-of-flight mass spectrometer including: a loop-orbit defining electrode (21) including an outer electrode (211) and inner electrode (212) located on the outside and inside of a loop orbit, respectively; an ion inlet (22); an ion outlet (23) provided in either the outer or inner electrode; a loop-flight voltage applier (28) configured to apply loop-flight voltages to the outer and inner electrodes, respectively; a set of deflecting electrodes (24) facing each other across a section of an n-th loop orbit, where n is a predetermined number, the deflecting electrodes including a first portion (241) which faces the n-th loop orbit and a second portion (242) which includes other portions; and a voltage applier (29) configured to apply deflecting voltages to the first portion so as to reverse the drifting direction of the ions flying in the n-th loop orbit, and a voltage to the second portion so as to create the loop-flight electric field.

公开(公告)号：US10593535B2

公开(公告)日：2020-03-17

申请号：US16320627

申请日：2016-09-21

Applicant: SHIMADZU CORPORATION

Inventor： Yusuke Tateishi

IPC: H01J49/42 ,  H01J49/14 ,  G01N27/62 ,  H01J49/06 ,  H01J49/10

Abstract: A mass spectrometer including: an ionization chamber (11) that generates ions from a sample, a collision cell (222) located downstream from the ionization chamber (11), a mass separation unit (2412) located downstream from the collision cell (222), an energy barrier unit (223) located between the collision cell (222) and the mass separation unit (2412), a voltage application unit (30) that applies a voltage to each of the ionization chamber (11), the collision cell (222), and the energy barrier unit (223), and a control unit (42) that controls the voltage application unit (30) such that a potential of the ionization chamber (11) is set to a first potential, a potential of the collision cell (222) is set to a second potential that is lower than the first potential, and a potential of the energy barrier unit (223) is set to a third potential between the first potential and the second potential.

公开(公告)号：US09679755B2

公开(公告)日：2017-06-13

申请号：US15049366

申请日：2016-02-22

Applicant: SHIMADZU CORPORATION

Inventor： Yusuke Tateishi ,  Kazuteru Takahashi ,  Hideki Sato

IPC: H01J49/10 ,  H01J49/14

CPC classification number: H01J49/147 ,  H01J27/024 ,  H01J27/205 ,  H01J49/067 ,  H01J49/145

Abstract: In an ion source 3 in which a repeller electrode 32 for forming a repelling electric field that repels ions toward an ion emission port 311 is provided inside of an ionization chamber 31, ion focusing electrodes 36 and 37 are respectively arranged between an electron introduction port 312 and a filament 34 and between an electron discharge port 313 and a counter filament 35. An electric field formed by applying a predetermined voltage to each of the ion focusing electrodes 36 and 37 intrudes into the ionization chamber 31 through the electron introduction port 312 and the electron discharge port 313, and becomes a focusing electric field that pushes the ions in an ion optical axis C direction. Ions at positions off a central part of the ionization chamber 31 receive the combined force of the force of the repelling electric field and the force of the focusing electric field, and move toward the ion emission port 311 while approaching the ion optical axis C. Accordingly, the amount of ions sent out from the ion emission port increases. Further, even if a charge-up phenomenon occurs, the ion trajectories less easily change, and the stability of the sensitivity can be enhanced.

公开(公告)号：US12154778B2

公开(公告)日：2024-11-26

申请号：US17632293

申请日：2020-08-11

Applicant: SHIMADZU CORPORATION

Inventor： Yoshihiro Ueno ,  Ryugo Maeda ,  Yusuke Tateishi ,  Hiroyuki Miura

IPC: H01J49/40 ,  H01J49/06 ,  H01J49/42

Abstract: An MT-TOFMS which is one mode of the present invention includes: a linear ion trap (2) configured to temporarily hold ions to be analyzed, and to eject the ions through an ion ejection opening (211) having a shape elongated in one direction; a loop flight section (3) configured to form a loop path (P) capable of making ions repeatedly fly; and a slit part (5) located on an ion path in which the ions ejected from the linear ion trap (2) travel until the ions are introduced into the loop path, the slit part configured to block a portion of the ions in a longitudinal direction of the ion ejection opening (211).