公开(公告)号：US11939387B2

公开(公告)日：2024-03-26

申请号：US18047039

申请日：2022-10-17

申请人： SHANGHAI MABGEEK BIOTECH. CO., LTD.

发明人： Chenghai Zhang ,  Jinlin Guo ,  Yujing Yuan

IPC分类号： C07K16/28 ,  A61K39/395 ,  A61P11/06 ,  C12N5/16 ,  A61K39/00 ,  C07K14/705

CPC分类号： C07K16/2866 ,  A61K39/3955 ,  A61P11/06 ,  C07K16/2896 ,  C12N5/16 ,  A61K39/00 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  C12N2510/02

摘要： The present invention discloses an antibody capable of binding to human interleukin 4 receptor alpha (hIL-4R alpha) and a preparation method and application thereof. The anti-hIL-4R alpha antibody can specifically bind to hIL-4R alpha, has good effects for inhibiting IL-4 and IL-13-induced cell line proliferation and the like, and can be applied to treatment of IL-4R alpha related diseases, such as immune-mediated inflammatory diseases.

公开(公告)号：US20240190979A1

公开(公告)日：2024-06-13

申请号：US18583713

申请日：2024-02-21

申请人： SHANGHAI MABGEEK BIOTECH CO., LTD.

发明人： Chenghai Zhang ,  Jinlin Guo ,  Yujing Yuan

IPC分类号： C07K16/28 ,  A61K39/00 ,  A61K39/395 ,  A61P11/06 ,  C12N5/16

CPC分类号： C07K16/2866 ,  A61K39/3955 ,  A61P11/06 ,  C07K16/2896 ,  C12N5/16 ,  A61K39/00 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  C12N2510/02

摘要： The present invention discloses an antibody capable of binding to human interleukin 4 receptor alpha (hIL-4R alpha) and a preparation method and application thereof. The anti-hIL-4R alpha antibody can specifically bind to hIL-4R alpha, has good effects for inhibiting IL-4 and IL-13-induced cell line proliferation and the like, and can be applied to treatment of IL-4R alpha related diseases, such as immune-mediated inflammatory diseases.

公开(公告)号：US20230203172A1

公开(公告)日：2023-06-29

申请号：US18047039

申请日：2022-10-17

申请人： SHANGHAI MABGEEK BIOTECH. CO., LTD.

发明人： Chenghai Zhang ,  Jinlin Guo ,  Yujing Yuan

IPC分类号： C07K16/28 ,  A61P11/06 ,  C12N5/16

CPC分类号： C07K16/2866 ,  A61P11/06 ,  C12N5/16 ,  A61K39/00

摘要： The present invention discloses an antibody capable of binding to human interleukin 4 receptor alpha (hIL-4R alpha) and a preparation method and application thereof. The anti-hIL-4R alpha antibody can specifically bind to hIL-4R alpha, has good effects for inhibiting IL-4 and IL-13-induced cell line proliferation and the like, and can be applied to treatment of IL-4R alpha related diseases, such as immune-mediated inflammatory diseases.