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公开(公告)号：US20200368433A1
公开(公告)日：2020-11-26
申请号：US16763679
申请日：2018-11-15
申请人： SANOFI
发明人： Michael Schabbach , Charlotte Emma Harvey , Congyi Huang , Timothy Charles Frearson , Alexander David Norman , Andrew Robert Potter , Gary Stacey
摘要： Systems and methods for mixing and/or reconstituting drugs are presented. A system may include an injection device, a vial, a needle, and a base station. The device has a chamber containing a first material. The vial has a chamber containing a second material. A drive unit of the base station moves the vial and/or the housing of the device relative to each other into an activated position. In the activated position, the needle is fluidly connected with the vial's chamber, and the drive unit is connected to a driver that moves the plunger in the axial direction of the device such that during fluid connection of the needle with the vial's chamber the first material is expelled from the device's chamber into the vial's chamber or the second material is expelled from the vial's chamber into the device's chamber.
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公开(公告)号：US11752263B2
公开(公告)日：2023-09-12
申请号：US16763679
申请日：2018-11-15
申请人： SANOFI
发明人： Michael Schabbach , Charlotte Emma Harvey , Congyi Huang , Timothy Charles Frearson , Alexander David Norman , Andrew Robert Potter , Gary Stacey
CPC分类号： A61M5/20 , A61M5/19 , A61M5/24 , A61M5/31576 , A61M5/34 , A61M2205/19
摘要： Systems and methods for mixing and/or reconstituting drugs are presented. A system may include an injection device, a vial, a needle, and a base station. The device has a chamber containing a first material. The vial has a chamber containing a second material. A drive unit of the base station moves the vial and/or the housing of the device relative to each other into an activated position. In the activated position, the needle is fluidly connected with the vial's chamber, and the drive unit is connected to a driver that moves the plunger in the axial direction of the device such that during fluid connection of the needle with the vial's chamber the first material is expelled from the device's chamber into the vial's chamber or the second material is expelled from the vial's chamber into the device's chamber.
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公开(公告)号：US11504473B2
公开(公告)日：2022-11-22
申请号：US16763282
申请日：2018-11-15
申请人： SANOFI
发明人： Michael Schabbach , Dieter Kadereit , Andrea Heiberger , Claus Geiger , Charlotte Emma Harvey , Congyi Huang , Timothy Charles Frearson , Alexander David Norman
摘要： A mixing and/or reconstitution system reduces the possibility of user error and provides a well mixed and/or reconstituted drug in a short time. The system comprises a device containing a first material within a first chamber, a housing, and a plunger, the plunger comprising a second chamber containing a second material, wherein one of the first and the second material is a fluid, and a movable element with an electric, magnetic, or paramagnetic characteristic, wherein the second chamber is initially closed; and a base unit comprising a recess for accommodation of the device, a control unit, and an electromagnetic unit which is adapted to produce an electromagnetic field penetrating the recess, wherein the control unit can electrically operate the electromagnetic unit such that the element contained in the second chamber moves in a direction of the device determined by the electromagnetic field and fluidly communicates the first and second chambers.
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公开(公告)号：US12109395B2
公开(公告)日：2024-10-08
申请号：US16764041
申请日：2018-11-15
申请人： SANOFI
发明人： Michael Schabbach , Claus Geiger , Andrea Heiberger , Dieter Kadereit , Charlotte Emma Harvey , Congyi Huang , Timothy Charles Frearson , Alexander David Norman
CPC分类号： A61M5/19 , A61J1/201 , A61J1/2093 , A61M5/2066 , A61M5/31596
摘要： The disclosure refers to a device, for example a cartridge, a syringe or an autoinjector, which reduces the possibility of user error and provides an easy and automatic operation during mixing and/or reconstitution. The device is adapted such that activation of the device causes movement one of a first piston and a second piston in second chamber in an axial direction of the device, thereby moving the other one of the first piston and the second piston into the same axial direction of the device, opening a fluid communication path between the second chamber and a first chamber of the device, and expelling a second material from the second chamber into the first chamber via the fluid communication path. The disclosure is further directed to a respective mixing and/or reconstitution method.
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公开(公告)号：US20200330686A1
公开(公告)日：2020-10-22
申请号：US16763282
申请日：2018-11-15
申请人： SANOFI
发明人： Michael Schabbach , Dieter Kadereit , Andrea Heiberger , Claus Geiger , Charlotte Emma Harvey , Congyi Huang , Timothy Charles Frearson , Alexander David Norman
摘要： A mixing and/or reconstitution system reduces the possibility of user error and provides a well mixed and/or reconstituted drug in a short time. The system comprises a device containing a first material within a first chamber, a housing, and a plunger, the plunger comprising a second chamber containing a second material, wherein one of the first and the second material is a fluid, and a movable element with an electric, magnetic, or paramagnetic characteristic, wherein the second chamber is initially closed; and a base unit comprising a recess for accommodation of the device, a control unit, and an electromagnetic unit which is adapted to produce an electromagnetic field penetrating the recess, wherein the control unit can electrically operate the electromagnetic unit such that the element contained in the second chamber moves in a direction of the device determined by the electromagnetic field and fluidly communicates the first and second chambers.
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公开(公告)号：US20200276388A1
公开(公告)日：2020-09-03
申请号：US16764041
申请日：2018-11-15
申请人： SANOFI
发明人： Michael Schabbach , Claus Geiger , Andrea Heiberger , Dieter Kadereit , Charlotte Emma Harvey , Congyi Huang , Timothy Charles Frearson , Alexander David Norman
摘要： The disclosure refers to a device, for example a cartridge, a syringe or an autoinjector, which reduces the possibility of user error and provides an easy and automatic operation during mixing and/or reconstitution. The device is adapted such that activation of the device causes movement one of a first piston and a second piston in second chamber in an axial direction of the device, thereby moving the other one of the first piston and the second piston into the same axial direction of the device, opening a fluid communication path between the second chamber and a first chamber of the device, and expelling a second material from the second chamber into the first chamber via the fluid communication path. The disclosure is further directed to a respective mixing and/or reconstitution method.
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