公开(公告)号：US20200209233A1

公开(公告)日：2020-07-02

申请号：US16730660

申请日：2019-12-30

Applicant: SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION

Inventor： Katie Campbell ,  Natasha Anna Boghosian ,  Natalie Fekete ,  Rachel Z. Pytel

IPC: G01N33/543

Abstract: This disclosure relates to containers (e.g., in the form of bags) comprising a fluoropolymer and containing a degradable carrier comprising biological agent-capturing moieties, to cell isolation systems comprising such containers, and to methods for cultivating a biological agent using such containers. In one embodiment, the disclosure provides a container having an outer surface and an inner surface, the inner surface comprising a fluoropolymer, and contained in the container, a degradable carrier; wherein the carrier comprises a plurality of biological agent-capturing moieties.

公开(公告)号：US11959056B2

公开(公告)日：2024-04-16

申请号：US16917331

申请日：2020-06-30

Applicant: Saint-Gobain Performance Plastics Corporation

Inventor： Robert G. Pleydon ,  Natasha Anna Boghosian ,  Jacob Andrews ,  Phillippe Jean Broussard

IPC: C12M1/00 ,  C12N1/04 ,  C12N5/0786

CPC classification number: C12M23/14 ,  C12M29/00 ,  C12N1/04 ,  C12N5/0645

Abstract: The disclosure relates generally to a cell culture apparatus and a cell culture method. One aspect of the disclosure provides a perfusion cell culture bag comprising one or more polymer films, having edges bonded together to form edges around an undivided interior compartment of the bag; first and second ports each formed in an exterior surface of the bag; first and second liquid-permeable tubes each extending into and in fluid communication with the interior compartment of the bag and operatively coupled to a respective port; and a third port formed in an exterior surface of the bag, the third port being in fluid communication with the interior compartment of the bag; wherein the first tube comprises a first inner support structure defining a central lumen of the tube and a first outer filter layer surrounding the first inner support structure.

公开(公告)号：US20200207539A1

公开(公告)日：2020-07-02

申请号：US16730477

申请日：2019-12-30

Applicant: SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION

Inventor： Natasha Anna Boghosian ,  Katie Campbell ,  Jian L. DIng ,  Natalie Fekete ,  Rachel Z. Pytel

IPC: B65D85/50 ,  C08L27/22 ,  C12M1/00

Abstract: This disclosure relates to containers and substrates comprising a fluoropolymer and having a textured inner surface and to methods for cultivating and/or isolating a biological agent using such containers and substrates. In one embodiment, the disclosure provides a container (e.g., in the form of a bag) having an outer surface and a textured inner surface, the inner surface comprising a fluoropolymer, wherein the textured inner surface comprises one or more of (a) a plurality of functional groups attached to the fluoropolymer, and (b) a pattern of spaced features, the features having an average spacing within the range of 0.1 μm to 200 μm.