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公开(公告)号：US11497780B2
公开(公告)日：2022-11-15
申请号：US16820463
申请日：2020-03-16
Inventor： Steven D. Goodman , Lauren O. Bakaletz , Michael Bailey , Gail Besner
IPC: A61K35/747 , A61K9/50 , A61K35/741 , A61K9/00 , A61K47/22 , A61K47/10 , A23L33/195 , A61K9/16 , A23L33/135 , A01N63/20 , A01N63/22 , A01N63/23 , A01N63/27
Abstract: Provided herein are compositions comprising a biocompatible microsphere, a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic. Methods for preparing and formulating the compositions and methods for treating or preventing a disease using the compositions are also provided.
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公开(公告)号：US11452748B2
公开(公告)日：2022-09-27
申请号：US16449320
申请日：2019-06-21
Inventor： Steven D. Goodman , Lauren O. Bakaletz , Gail Besner , Michael Bailey
IPC: A61K35/747 , A61K9/16 , A23L33/135 , A23L33/195
Abstract: Provided herein are compositions comprising a biocompatible microsphere, a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic. Methods for preparing and formulating the compositions and methods for treating or preventing a disease using the compositions are also provided.
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公开(公告)号：US20240075079A1
公开(公告)日：2024-03-07
申请号：US17955413
申请日：2022-09-28
Inventor： Steven D. Goodman , Lauren O. Bakaletz , Michael Bailey , Gail Besner
IPC: A61K35/747 , A01N63/20 , A01N63/22 , A01N63/23 , A01N63/27 , A23L33/135 , A23L33/195 , A61K9/00 , A61K9/16 , A61K9/50 , A61K35/741 , A61K47/10 , A61K47/22
CPC classification number: A61K35/747 , A01N63/20 , A01N63/22 , A01N63/23 , A01N63/27 , A23L33/135 , A23L33/195 , A61K9/0031 , A61K9/1647 , A61K9/1652 , A61K9/1658 , A61K9/50 , A61K35/741 , A61K47/10 , A61K47/22 , A23V2002/00 , A23V2200/3202 , A23V2200/3204
Abstract: Provided herein are compositions comprising a biocompatible microsphere, a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic. Methods for preparing and formulating the compositions and methods for treating or preventing a disease using the compositions are also provided.
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公开(公告)号：US20220011312A1
公开(公告)日：2022-01-13
申请号：US17379878
申请日：2021-07-19
Applicant: Li Chen , Yu Zhou , RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
Inventor： Li Chen , Yu Zhou , David Brigstock , Gail Besner
IPC: G01N33/574 , A61K45/06 , C12Q1/6886
Abstract: The present disclosure provides a novel method for monitoring the conversion of oral precancerous lesions to oral cancers, including monitoring changes in oral exosome concentrations in a subject, thereby determining the state of the disease and the risk of carcinogenesis. The disclosure also relates to a detection kit for use in the above method.
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公开(公告)号：US20230285475A1
公开(公告)日：2023-09-14
申请号：US17885446
申请日：2022-08-10
Inventor： Steven D. Goodman , Lauren O. Bakaletz , Gail Besner , Michael Bailey
IPC: A61K35/747 , A23L33/135 , A23L33/195 , A61K9/16
CPC classification number: A61K35/747 , A23L33/135 , A23L33/195 , A61K9/1611 , A61K9/1647 , A61K9/1652 , A61K9/1658 , A23V2200/3202 , A23V2200/3204 , A23V2002/00
Abstract: Provided herein are compositions comprising a biocompatible microsphere, a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic. Methods for preparing and formulating the compositions and methods for treating or preventing a disease using the compositions are also provided.
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Patent Agency Ranking
公开(公告)号：US20220136060A1
公开(公告)日：2022-05-05
申请号：US17367220
申请日：2021-07-02
Applicant: Li Chen , Yu Zhou , RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
Inventor： Li Chen , Yu Zhou , David Brigstock , Gail Besner
IPC: C12Q1/6886 , A61K33/243 , A61K31/713
Abstract: The present invention provides novel methods and kits for determining whether a subject is suffering from cisplatin-containing resistant ovarian and methods for treating and reversing resistance.
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公开(公告)号：US20210290701A1
公开(公告)日：2021-09-23
申请号：US17265505
申请日：2019-08-02
Inventor： Gail Besner , Steven D. Goodman , Michael Bailey
IPC: A61K35/747 , A61K9/50 , A61K35/742 , A61K35/745 , A61K35/744 , A61K47/10 , A61K47/22 , A61P1/00
Abstract: Provided herein are prenatal methods comprising administering an effective amount of a biocompatible microsphere comprising a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic.
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公开(公告)号：US20200155620A1
公开(公告)日：2020-05-21
申请号：US16449320
申请日：2019-06-21
Inventor： Steven D. Goodman , Lauren O. Bakaletz , Gail Besner , Michael Bailey
IPC: A61K35/747 , A61K9/16 , A23L33/195 , A23L33/135
Abstract: Provided herein are compositions comprising a biocompatible microsphere, a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic. Methods for preparing and formulating the compositions and methods for treating or preventing a disease using the compositions are also provided.
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公开(公告)号：US20180000878A1
公开(公告)日：2018-01-04
申请号：US15649352
申请日：2017-07-13
Inventor： Steven D. Goodman , Lauren O. Bakaletz , Michael Bailey , Gail Besner
CPC classification number: A61K35/747 , A01N63/00 , A23L33/135 , A23L33/195 , A23V2002/00 , A23V2200/3202 , A23V2200/3204 , A61K9/0031 , A61K9/1647 , A61K9/1652 , A61K9/1658 , A61K9/50 , A61K35/741 , A61K47/10 , A61K47/22
Abstract: Provided herein are compositions comprising a biocompatible microsphere, a biofilm-generating probiotic bacterium, a prebiotic, and/or a prebiofilmic. Methods for preparing and formulating the compositions and methods for treating or preventing a disease using the compositions are also provided.
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公开(公告)号：US20220162700A1
公开(公告)日：2022-05-26
申请号：US17367201
申请日：2021-07-02
Applicant: Li Chen , Yu Chou , RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
Inventor： Li Chen , Yu Zhou , David Brigstock , Gail Besner
IPC: C12Q1/6883 , C12N15/113 , C12N15/10
Abstract: The present invention provides novel methods and kits for determining whether a subject is suffering from endometriosis or an associated disorder. It also provides methods and kits for determining whether a subject suffering from endometriosis or an associated disorder is more or less likely to be responsive to a therapy to treat endometriosis or an associated disorder.
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