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1.发明授权公开(公告)号：US12115386B2
公开(公告)日：2024-10-15
申请号：US17571273
申请日：2022-01-07
Applicant: RefleXion Medical, Inc.
Inventor： Yevgen Voronenko , Debashish Pal , David Quentin Larkin , George Zdasiuk , Jayakrishnan Janardhanan , Michael Kirk Owens , Peter Demetri Olcott
IPC: A61N5/10
CPC classification number: A61N5/1031 , A61N5/1039 , A61N5/1043 , A61N5/1045 , A61N5/1084
Abstract: Disclosed herein are methods for patient setup and patient target region localization for the irradiation of multiple patient target regions in a single treatment session. Virtual localization is a method that can be used to register a patient target region without requiring that the patient is physically moved using the patient platform. Instead, the planned fluence is updated to reflect the current location of the patient target region by selecting a localization reference in the localization image, calculating a localization function based on the localization reference point, and calculating the delivery fluence by convolving the localization function with a shift-invariant firing filter. Mosaic multi-target localization partitions a planned fluence map for multiple patient target regions into sub-regions that can be individually localized. De-coupled multi-target localization involves generating a separate planned fluence map for each target but constraining a cumulative fluence map to ensure dosimetric goals are met.
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公开(公告)号：US11896848B2
公开(公告)日：2024-02-13
申请号：US17375586
申请日：2021-07-14
Applicant: RefleXion Medical, Inc.
Inventor： Jayakrishnan Janardhanan , Michael Kirk Owens
IPC: A61N5/10
CPC classification number: A61N5/1049 , A61N5/103 , A61N5/107 , A61N5/1031 , A61N5/1037 , A61N5/1039 , A61N5/1045 , A61N5/1047 , A61N5/1048 , A61N5/1081 , A61N5/1082 , A61N2005/1052 , A61N2005/1061 , A61N2005/1091
Abstract: Disclosed herein are methods for patient setup and registration for the irradiation of target tissue regions. A method for positioning a patient for radiation therapy may include acquiring an image of a first patient target region and a second patient target region. A first set of patient position-shift vectors may be calculated based on the acquired image and a treatment planning image of the first patient target region. A second set of patient position-shift vectors may be calculated based on the acquired image, a treatment planning image of the second patient target region, and the first set of patient position-shift vectors. The patient may be positioned according to the first set of patient position-shift vectors in a first location. The patient may be moved to a second location and positioned according to the second set of patient position-shift vectors.
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公开(公告)号：US12029921B2
公开(公告)日：2024-07-09
申请号：US17852067
申请日：2022-06-28
Applicant: RefleXion Medical, Inc.
Inventor： Thomas Leroy Laurence, Jr. , Jayakrishnan Janardhanan
CPC classification number: A61N5/1049 , A61B34/10 , A61N5/1081 , A61B2034/105 , A61B2090/367 , A61B2090/373 , A61N2005/105 , A61N2005/1059 , A61N5/107 , A61N2005/1074 , A61N2005/1076
Abstract: Disclosed herein are systems and methods for real-time monitoring of patient position and/or location during a radiation treatment session. Images acquired of a patient during a treatment session can be used to calculate the patient's position and/or location with respect to the components of the radiation therapy system. One variation of a radiation therapy system includes a circular gantry with a rotatable ring coupled to a stationary frame, a therapeutic radiation source mounted on the rotatable ring, and a patient-monitoring imaging system mounted on the rotatable ring. The patient-monitoring system may have one or more image sensors or cameras disposed on the rotatable ring within a bore region of the radiation therapy system, and may be configured to acquire image data as the ring rotates.
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Patent Agency Ranking
公开(公告)号：US20240082605A1
公开(公告)日：2024-03-14
申请号：US18472034
申请日：2023-09-21
Applicant: RefleXion Medical, Inc.
Inventor： Yevgen VORONENKO , Jayakrishnan Janardhanan , Debashish Pal , Rostem Bassalow , Peter Demetri Olcott , Michael Kirk Owens
CPC classification number: A61N5/1079 , A61B6/035 , A61B6/037 , A61B6/0407 , A61B6/4435 , A61B6/54 , A61N5/103 , A61N5/1045 , A61N5/1049 , A61N5/107 , A61N5/1071 , A61N5/1075 , A61N5/1081 , A61N2005/1052 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061 , A61N5/1068 , A61N2005/1072
Abstract: Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.
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公开(公告)号：US12233286B2
公开(公告)日：2025-02-25
申请号：US18472034
申请日：2023-09-21
Applicant: RefleXion Medical, Inc.
Inventor： Yevgen Voronenko , Jayakrishnan Janardhanan , Debashish Pal , Rostem Bassalow , Peter Demetri Olcott , Michael Kirk Owens
Abstract: Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.
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公开(公告)号：US11801398B2
公开(公告)日：2023-10-31
申请号：US17831105
申请日：2022-06-02
Applicant: RefleXion Medical, Inc.
Inventor： Yevgen Voronenko , Jayakrishnan Janardhanan , Debashish Pal , Rostem Bassalow , Peter Demetri Olcott , Michael Kirk Owens
CPC classification number: A61N5/1079 , A61B6/035 , A61B6/037 , A61B6/0407 , A61B6/4435 , A61B6/54 , A61N5/103 , A61N5/107 , A61N5/1045 , A61N5/1049 , A61N5/1071 , A61N5/1075 , A61N5/1081 , A61N5/1068 , A61N2005/1052 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061 , A61N2005/1072
Abstract: Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.
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公开(公告)号：US11369806B2
公开(公告)日：2022-06-28
申请号：US16191131
申请日：2018-11-14
Applicant: RefleXion Medical, Inc.
Inventor： Thomas Leroy Laurence, Jr. , Jayakrishnan Janardhanan
Abstract: Disclosed herein are systems and methods for real-time monitoring of patient position and/or location during a radiation treatment session. Images acquired of a patient during a treatment session can be used to calculate the patient's position and/or location with respect to the components of the radiation therapy system. One variation of a radiation therapy system includes a circular gantry with a rotatable ring coupled to a stationary frame, a therapeutic radiation source mounted on the rotatable ring, and a patient-monitoring imaging system mounted on the rotatable ring. The patient-monitoring system may have one or more image sensors or cameras disposed on the rotatable ring within a bore region of the radiation therapy system, and may be configured to acquire image data as the ring rotates.
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公开(公告)号：US11358008B2
公开(公告)日：2022-06-14
申请号：US16274962
申请日：2019-02-13
Applicant: RefleXion Medical, Inc.
Inventor： Yevgen Voronenko , Jayakrishnan Janardhanan , Debashish Pal , Rostem Bassalow , Peter Demetri Olcott , Michael Kirk Owens
Abstract: Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.
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