公开(公告)号：US11975220B2

公开(公告)日：2024-05-07

申请号：US16887852

申请日：2020-05-29

申请人： RefleXion Medical, Inc.

发明人： Brent Harper ,  David Larkin ,  David Nett

IPC分类号： A61N5/10 ,  A61N5/00 ,  G21K1/04

CPC分类号： A61N5/1081 ,  A61N5/1045 ,  A61N5/1049 ,  A61N2005/005 ,  A61N2005/1052 ,  A61N2005/1091 ,  A61N2005/1094 ,  G21K1/046

摘要： Disclosed herein are radiation therapy systems and methods. These radiation therapy systems and methods are used for emission-guided radiation therapy, where gamma rays from markers or tracers that are localized to patient tumor regions are detected and used to direct radiation to the tumor. The radiation therapy systems described herein comprise a gantry comprising a rotatable ring coupled to a stationary frame via a rotating mechanism such that the rotatable ring rotates up to about 70 RPM, a radiation source (e.g., MV X-ray source) mounted on the rotatable ring, and one or more PET detectors mounted on the rotatable ring.

公开(公告)号：US10695586B2

公开(公告)日：2020-06-30

申请号：US15814222

申请日：2017-11-15

申请人： RefleXion Medical, Inc.

发明人： Brent Harper ,  Robert Wiggers ,  David Larkin ,  David Meer ,  David Nett ,  Rostem Bassalow ,  Peter Olcott ,  Chris Julian ,  Brent Dolan ,  William Jorge Pearce

IPC分类号： A61N5/10 ,  A61N5/00 ,  G21K1/04

摘要： Disclosed herein are radiation therapy systems and methods. These radiation therapy systems and methods are used for emission-guided radiation therapy, where gamma rays from markers or tracers that are localized to patient tumor regions are detected and used to direct radiation to the tumor. The radiation therapy systems described herein comprise a gantry comprising a rotatable ring coupled to a stationary frame via a rotating mechanism such that the rotatable ring rotates up to about 70 RPM, a radiation source (e.g., MV X-ray source) mounted on the rotatable ring, and one or more PET detectors mounted on the rotatable ring.

公开(公告)号：US12090340B2

公开(公告)日：2024-09-17

申请号：US17696662

申请日：2022-03-16

申请人： RefleXion Medical, Inc.

发明人： Brent Harper ,  David Quentin Larkin ,  Peter Demetri Olcott ,  George Andrew Zdasiuk ,  David Nett ,  Victor Carboni

IPC分类号： A61N5/10 ,  H05H9/00

CPC分类号： A61N5/1048 ,  A61N5/1045 ,  A61N5/1081 ,  A61N5/1083 ,  H05H9/00 ,  H05H2277/11

摘要： Disclosed herein are systems and methods for rapidly delivering high doses of radiation, also known as, flash dose radiotherapy or flash radiotherapy. One variation of a system for flash radiotherapy has a plurality of therapeutic radiation sources on a support structure (e.g., a gantry or arm) and configured to toward a patient target region, and a controller in communication with all of the therapeutic radiation sources. The controller is configured to activate the plurality of therapeutic radiation sources simultaneously so that the patient target region rapidly receives a high dose of radiation, e.g. the entire prescribed dose of radiation. In some variations, a flash radiotherapy system has a pulsed, high-power source that may be used to generate an X-ray pulse that delivers a dose having a dose rate from about 7.5 Gy/s to about 70 Gy/s. Flash radiotherapy systems may also include one or more imaging systems mounted on the support structure.