公开(公告)号：US20160266020A1

公开(公告)日：2016-09-15

申请号：US15036811

申请日：2014-11-13

Applicant: RANDOX LABORATORIES LTD

Inventor： Michael Veitinger ,  Maria Zellner

IPC: G01N1/40 ,  C12Q1/48

CPC classification number: G01N1/4077 ,  C12Q1/485 ,  G01N33/6842 ,  G01N33/86

Abstract: The present invention provides a novel method of in vitro sample preparation for the analysis of proteins. In a first aspect, the present invention is a method comprising the separation and individual treatment of blood platelets and platelet-poor plasma obtained from a platelet-rich plasma sample. This allows for optimal treatment of both fractions and overcomes many of the problems associated with current methods. In a second aspect of the present invention the platelet sample preparation method can be implemented before a biochip based immunoassay for the detection of platelet proteins in combination with plasma proteins.

Abstract translation: 本发明提供了用于分析蛋白质的体外样品制备的新方法。 在第一方面，本发明是一种包括从富含血小板的血浆样品中分离和单独处理血小板和血小板不足血浆的方法。 这允许对两个级分进行最佳处理并克服与当前方法相关的许多问题。 在本发明的第二方面，血小板样品制备方法可以在用于检测与血浆蛋白质组合的血小板蛋白质的基于生物芯片的免疫测定之前实施。

公开(公告)号：US10209167B2

公开(公告)日：2019-02-19

申请号：US15036811

申请日：2014-11-13

Applicant: Randox Laboratories Ltd.

Inventor： Michael Veitinger ,  Maria Zellner

IPC: G01N1/40 ,  C12Q1/48 ,  G01N33/68 ,  G01N33/86

Abstract: The present invention provides a novel method of in vitro sample preparation for the analysis of proteins. In a first aspect, the present invention is a method comprising the separation and individual treatment of blood platelets and platelet-poor plasma obtained from a platelet-rich plasma sample. This allows for optimal treatment of both fractions and overcomes many of the problems associated with current methods. In a second aspect of the present invention the platelet sample preparation method can be implemented before a biochip based immunoassay for the detection of platelet proteins in combination with plasma proteins.