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    Method and apparatus for discriminating cardiac signals in a medical device based on wavelet decomposition analysis
    1.
    发明授权
    Method and apparatus for discriminating cardiac signals in a medical device based on wavelet decomposition analysis 有权
    基于小波分解分析来鉴别医疗装置中的心脏信号的方法和装置

    公开(公告)号：US08676289B2

    公开(公告)日：2014-03-18

    申请号：US11744455

    申请日：2007-05-04

    申请人： Raja N. Ghanem ,  Troy E. Jackson

    发明人： Raja N. Ghanem ,  Troy E. Jackson

    IPC分类号： A61B5/0428

    CPC分类号： A61B5/0464 ,  A61B5/0422 ,  A61B5/0424 ,  A61B5/046 ,  A61B5/726 ,  A61N1/362 ,  A61N1/3706 ,  G06K9/00536 ,  G06K9/527

    摘要： A method of detecting cardiac signals in a medical device that includes decomposing a cardiac signal using a wavelet function at a plurality of scales to form a corresponding wavelet transform, determining approximation coefficients in response to the plurality of scales, reconstructing a first wavelet representation of the wavelet transform using predetermined approximation coefficients of the determined approximation coefficients, and evaluating the detected cardiac signals in response to the reconstructing.

    摘要翻译： 一种检测医疗装置中的心脏信号的方法，包括使用多个尺度的小波函数分解心脏信号以形成对应的小波变换，响应于所述多个标度确定近似系数，重建所述多个尺度的第一小波表示 使用所确定的近似系数的预定近似系数的小波变换，以及响应于重建来评估检测到的心脏信号。

    Method and apparatus for discriminating cardiac signals in a medical device based on wavelet decomposition analysis
    2.
    发明授权
    Method and apparatus for discriminating cardiac signals in a medical device based on wavelet decomposition analysis 有权
    基于小波分解分析来鉴别医疗装置中的心脏信号的方法和装置

    公开(公告)号：US07894886B2

    公开(公告)日：2011-02-22

    申请号：US11744475

    申请日：2007-05-04

    申请人： Raja N. Ghanem ,  Troy E. Jackson

    发明人： Raja N. Ghanem ,  Troy E. Jackson

    IPC分类号： A61B5/0428

    CPC分类号： A61B5/0464 ,  A61B5/0422 ,  A61B5/0424 ,  A61B5/046 ,  A61B5/726 ,  A61N1/362 ,  A61N1/3706 ,  G06K9/00536 ,  G06K9/527

    摘要： A method and device for detecting cardiac signals in a medical device that includes decomposing sensed cardiac signals using a wavelet function to form a corresponding wavelet transform, generating a first wavelet representation corresponding to the wavelet transform that is responsive to RR intervals of the sensed cardiac signals, generating a second wavelet representation that is not responsive to RR intervals associated with the sensed cardiac signals, and determining a device failure in response to the first wavelet representation and the second wavelet representation. The method and device may also include decomposing sensed cardiac signals using a wavelet function to form a corresponding wavelet transform, generating a wavelet representation that is not responsive to RR intervals of the sensed cardiac signals, determining RR intervals associated with the sensed cardiac signals, and determining a device failure in response to the first wavelet representation and the determined RR intervals.

    摘要翻译： 一种用于检测医疗装置中的心脏信号的方法和装置，其包括使用小波函数分解感测到的心脏信号以形成对应的小波变换，产生对应于小波变换的第一小波表示，所述小波变换响应于感测的心脏信号的RR间隔 产生不响应于与感测到的心脏信号相关联的RR间隔的第二小波表示，以及响应于第一小波表示和第二小波表示来确定设备故障。 所述方法和装置还可以包括使用小波函数分解感测到的心脏信号以形成相应的小波变换，产生不响应感测的心脏信号的RR间隔的小波表示，确定与感测到的心脏信号相关联的RR间隔，以及 响应于第一小波表示和所确定的RR间隔来确定设备故障。

    Method and apparatus for discriminating cardiac signals in a medical device based on wavelet decomposition analysis
    3.
    发明授权
    Method and apparatus for discriminating cardiac signals in a medical device based on wavelet decomposition analysis 有权
    基于小波分解分析来鉴别医疗装置中的心脏信号的方法和装置

    公开(公告)号：US07774063B2

    公开(公告)日：2010-08-10

    申请号：US11744484

    申请日：2007-05-04

    申请人： Raja N. Ghanem ,  Troy E. Jackson

    发明人： Raja N. Ghanem ,  Troy E. Jackson

    IPC分类号： A61N1/37

    CPC分类号： A61B5/0464 ,  A61B5/0422 ,  A61B5/0424 ,  A61B5/046 ,  A61B5/726 ,  A61N1/362 ,  A61N1/3706 ,  G06K9/00536 ,  G06K9/527

    摘要： A method and device for detecting cardiac signals in a medical device that includes decomposing sensed cardiac signals using a wavelet function to form a corresponding wavelet transform, generating a first wavelet representation corresponding to the wavelet transform that is responsive to RR intervals of the sensed cardiac signals, generating a second wavelet representation that is not responsive to RR intervals associated with the sensed cardiac signals, determining a no lead failure zone in response to the first wavelet representation and the second wavelet representation, and distinguishing the cardiac event from a device failure in response to the determined no lead failure zone. The method and device may also include generating a wavelet representation corresponding to the wavelet transform that is not responsive to RR intervals of the sensed cardiac signals, determining RR intervals associated with the sensed cardiac signals, and determining a no lead failure zone in response to the wavelet representation and the determined RR intervals.

    摘要翻译： 一种用于检测医疗装置中的心脏信号的方法和装置，其包括使用小波函数分解感测到的心脏信号以形成对应的小波变换，产生对应于小波变换的第一小波表示，所述小波变换响应于感测的心脏信号的RR间隔 ，产生不响应于与感测的心脏信号相关联的RR间隔的第二小波表示，响应于第一小波表示和第二小波表示确定无引线故障区域，并将心脏事件与响应中的设备故障区分开 确定无铅故障区。 所述方法和装置还可以包括生成对应于小波变换的小波变换，所述小波变换不响应于感测的心脏信号的RR间隔，确定与所感测的心脏信号相关联的RR间隔，以及响应于 小波表示和确定的RR间隔。

    METHOD AND APPARATUS FOR DISCRIMINATING CARDIAC SIGNALS IN A MEDICAL DEVICE BASED ON WAVELET DECOMPOSITION ANALYSIS
    4.
    发明申请
    METHOD AND APPARATUS FOR DISCRIMINATING CARDIAC SIGNALS IN A MEDICAL DEVICE BASED ON WAVELET DECOMPOSITION ANALYSIS 有权
    基于小波分解分析的医疗设备鉴别心脏信号的方法与装置

    公开(公告)号：US20070260152A1

    公开(公告)日：2007-11-08

    申请号：US11744475

    申请日：2007-05-04

    申请人： Raja N. Ghanem ,  Troy E. Jackson

    发明人： Raja N. Ghanem ,  Troy E. Jackson

    IPC分类号： A61B5/04

    CPC分类号： A61B5/0464 ,  A61B5/0422 ,  A61B5/0424 ,  A61B5/046 ,  A61B5/726 ,  A61N1/362 ,  A61N1/3706 ,  G06K9/00536 ,  G06K9/527

    摘要： A method and device for detecting cardiac signals in a medical device that includes decomposing sensed cardiac signals using a wavelet function to form a corresponding wavelet transform, generating a first wavelet representation corresponding to the wavelet transform that is responsive to RR intervals of the sensed cardiac signals, generating a second wavelet representation that is not responsive to RR intervals associated with the sensed cardiac signals, and determining a device failure in response to the first wavelet representation and the second wavelet representation. The method and device may also include decomposing sensed cardiac signals using a wavelet function to form a corresponding wavelet transform, generating a wavelet representation that is not responsive to RR intervals of the sensed cardiac signals, determining RR intervals associated with the sensed cardiac signals, and determining a device failure in response to the first wavelet representation and the determined RR intervals.

    摘要翻译： 一种用于检测医疗装置中的心脏信号的方法和装置，其包括使用小波函数分解感测到的心脏信号以形成对应的小波变换，产生对应于小波变换的第一小波表示，所述小波变换响应于感测的心脏信号的RR间隔 产生不响应于与感测到的心脏信号相关联的RR间隔的第二小波表示，以及响应于第一小波表示和第二小波表示来确定设备故障。 所述方法和装置还可以包括使用小波函数分解感测到的心脏信号以形成相应的小波变换，产生不响应感测的心脏信号的RR间隔的小波表示，确定与感测到的心脏信号相关联的RR间隔，以及 响应于第一小波表示和所确定的RR间隔来确定设备故障。

    METHOD AND APPARATUS FOR DISCRIMINATING CARDIAC SIGNALS IN A MEDICAL DEVICE BASED ON WAVELET DECOMPOSITION ANALYSIS
    6.
    发明申请
    METHOD AND APPARATUS FOR DISCRIMINATING CARDIAC SIGNALS IN A MEDICAL DEVICE BASED ON WAVELET DECOMPOSITION ANALYSIS 有权
    基于小波分解分析的医疗设备鉴别心脏信号的方法与装置

    公开(公告)号：US20070260153A1

    公开(公告)日：2007-11-08

    申请号：US11744484

    申请日：2007-05-04

    申请人： Raja N. Ghanem ,  Troy E. Jackson

    发明人： Raja N. Ghanem ,  Troy E. Jackson

    IPC分类号： A61B5/04

    CPC分类号： A61B5/0464 ,  A61B5/0422 ,  A61B5/0424 ,  A61B5/046 ,  A61B5/726 ,  A61N1/362 ,  A61N1/3706 ,  G06K9/00536 ,  G06K9/527

    摘要： A method and device for detecting cardiac signals in a medical device that includes decomposing sensed cardiac signals using a wavelet function to form a corresponding wavelet transform, generating a first wavelet representation corresponding to the wavelet transform that is responsive to RR intervals of the sensed cardiac signals, generating a second wavelet representation that is not responsive to RR intervals associated with the sensed cardiac signals, determining a no lead failure zone in response to the first wavelet representation and the second wavelet representation, and distinguishing the cardiac event from a device failure in response to the determined no lead failure zone. The method and device may also include generating a wavelet representation corresponding to the wavelet transform that is not responsive to RR intervals of the sensed cardiac signals, determining RR intervals associated with the sensed cardiac signals, and determining a no lead failure zone in response to the wavelet representation and the determined RR intervals.

    摘要翻译： 一种用于检测医疗装置中的心脏信号的方法和装置，其包括使用小波函数分解感测到的心脏信号以形成对应的小波变换，产生对应于小波变换的第一小波表示，所述小波变换响应于感测的心脏信号的RR间隔 ，产生不响应于与感测的心脏信号相关联的RR间隔的第二小波表示，响应于第一小波表示和第二小波表示确定无引线故障区域，并将心脏事件与响应中的设备故障区分开 确定无铅故障区。 所述方法和装置还可以包括生成对应于小波变换的小波变换，所述小波变换对所检测到的心脏信号的RR间隔无响应，确定与感测的心脏信号相关联的RR间隔，以及响应于 小波表示和确定的RR间隔。

    Detection of T-wave alternans phase reversal for arrhythmia prediction and sudden cardiac death risk stratification
    7.
    发明授权
    Detection of T-wave alternans phase reversal for arrhythmia prediction and sudden cardiac death risk stratification 有权
    检测心律失常预测和心源性猝死危险分层的T波交替相逆转

    公开(公告)号：US08620414B2

    公开(公告)日：2013-12-31

    申请号：US12749753

    申请日：2010-03-30

    申请人： Raja N. Ghanem ,  Xiaohong Zhou

    发明人： Raja N. Ghanem ,  Xiaohong Zhou

    IPC分类号： A61B5/0452

    CPC分类号： A61B5/0452 ,  A61B5/02405 ,  A61B5/7264 ,  A61B5/7275 ,  A61N1/36507 ,  G06F19/00

    摘要： An implantable medical device and associated method for classifying a patient's risk for arrhythmias by sensing a cardiac electrogram (EGM) signal and selecting a first pair of T-wave signals and a second pair of T-wave signals. A first difference between the two T-wave signals of the first pair is compared to a second difference between the two T-wave signals of the second pair. A T-wave alternans phase reversal is detected in response to comparing the first difference and the second difference, and the patient's arrhythmia risk is classified in response to detecting the phase reversal.

    摘要翻译： 一种用于通过感测心电图（EGM）信号和选择第一对T波信号和第二对T波信号来分类患者心律失常风险的可植入医疗装置和相关方法。 将第一对的两个T波信号之间的第一个差异与第二对的两个T波信号之间的第二个差值进行比较。 响应于比较第一个差异和第二个差异，检测到T波交替相位逆转，并且响应于检测相位反转来分类患者的心律失常风险。

    Method and apparatus for detecting arrhythmias in a medical device
    9.
    发明授权
    Method and apparatus for detecting arrhythmias in a medical device 有权
    用于检测医疗装置中的心律失常的方法和装置

    公开(公告)号：US07761150B2

    公开(公告)日：2010-07-20

    申请号：US11380846

    申请日：2006-04-28

    申请人： Raja N. Ghanem ,  Robert W. Stadler ,  Xusheng Zhang

    发明人： Raja N. Ghanem ,  Robert W. Stadler ,  Xusheng Zhang

    IPC分类号： A61N1/368

    CPC分类号： A61N1/3987 ,  A61B5/04011 ,  A61B5/0422 ,  A61B5/0456 ,  A61B5/046 ,  A61B5/0464 ,  A61B5/0468 ,  A61B5/4836 ,  A61B5/686 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7239 ,  A61N1/05 ,  A61N1/3621 ,  A61N1/3925 ,  A61N1/3956 ,  Y10S128/901 ,  Y10S128/902

    摘要： A method of detecting a cardiac event in a medical device that includes determining a first characteristic in response to cardiac signals sensed along a first sensing vector over a predetermined sensing window and in response to cardiac signals sensed along a second sensing vector over the predetermined sensing window, determining a second characteristic in response to cardiac signals sensed along the first sensing vector over the predetermined sensing window and in response to cardiac signals sensed along the second sensing vector over the predetermined sensing window, and determining a third characteristic in response to cardiac signals sensed along the first sensing vector over the predetermined sensing window and in response to cardiac signals sensed along the second sensing vector over the predetermined sensing window.

    摘要翻译： 一种检测医疗设备中的心脏事件的方法，包括响应于沿着预定感测窗口沿着第一感测向量感测的心脏信号并且响应于沿着预定感测窗口沿着第二感测向量感测的心脏信号来确定第一特性 ，响应于沿着预定感测窗口沿着第一感测向量感测的心脏信号并且响应于沿着预定感测窗口沿着第二感测向量感测到的心脏信号，确定响应于感测到的心脏信号的第三特性的第二特性 沿着预定感测窗口上的第一感测向量，并且响应于沿着预定感测窗口沿着第二感测向量感测的心脏信号。

    Electrodes array for a pacemaker
    10.
    发明授权
    Electrodes array for a pacemaker 有权
    用于起搏器的电极阵列

    公开(公告)号：US07496408B2

    公开(公告)日：2009-02-24

    申请号：US11004498

    申请日：2004-12-03

    申请人： Raja N. Ghanem ,  Walter H. Olson

    发明人： Raja N. Ghanem ,  Walter H. Olson

    IPC分类号： A61N1/04

    CPC分类号： A61N1/05 ,  A61N1/362

    摘要： A cardiac pacemaker and method of its use. The pacemaker is provided with a pacing electrode array configured for location at a left anterior portion of a patient's thorax between the patients third and sixth ribs, outside the patient's thoracic cavity. The pacing electrode array includes multiple pacing electrodes and preferably includes one or more steering electrodes for configuring the electrical field produced by delivery of pacing pulses to avoid unwanted nerve and muscle stimulation while allowing cardiac stimulation. The electrode array may be located subcutaneously, submuscularly or on the patient's skin.

    摘要翻译： 心脏起搏器及其使用方法。 起搏器设置有起搏电极阵列，其配置用于位于患者胸腔之间的患者胸部的左前部之间，患者第三肋和第六肋之间，位于患者胸腔外。 起搏电极阵列包括多个起搏电极，并且优选地包括一个或多个转向电极，用于配置通过递送起搏脉冲产生的电场，以避免不必要的神经和肌肉刺激同时允许心脏刺激。 电极阵列可以皮下，肌内或病人的皮肤上。