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Patent Agency Ranking
公开(公告)号：US20240384437A1
公开(公告)日：2024-11-21
申请号：US18430601
申请日：2024-02-01
Applicant: RULES-BASED MEDICINE INC.
Inventor： Andrew Raymon Morton BRADBURY , Michael Frank ERASMUS , Andre TEIXEIRA
Abstract: Antibody libraries comprising a plurality of heavy chain variable domains and/or a plurality of light chain variable domains, which comprise complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or more features of such members. Further, the antibody libraries comprise members having heavy chain and/or light chain CDRs not found in the same naturally-occurring human antibody.
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公开(公告)号：US20240384440A1
公开(公告)日：2024-11-21
申请号：US18592499
申请日：2024-02-29
Applicant: RULES-BASED MEDICINE INC.
Inventor： Andrew Raymon Morton BRADBURY , Michael Frank ERASMUS , Andre TEIXEIRA
Abstract: Antibody libraries comprising a plurality of heavy chain variable domains and/or a plurality of light chain variable domains, which comprise complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or more features of such members. Further, the antibody libraries comprise members having heavy chain and/or light chain CDRs not found in the same naturally-occurring human antibody.
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公开(公告)号：US20240229297A1
公开(公告)日：2024-07-11
申请号：US18592473
申请日：2024-02-29
Applicant: RULES-BASED MEDICINE INC.
Inventor： Andrew Raymon Morton BRADBURY , Michael Frank ERASMUS , Andre TEIXEIRA
CPC classification number: C40B40/10 , C12N15/1037 , C12N15/81 , C40B40/08 , C40B50/06
Abstract: Antibody libraries comprising a plurality of heavy chain variable domains and/or a plurality of light chain variable domains, which comprise complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or more features of such members. Further, the antibody libraries comprise members having heavy chain and/or light chain CDRs not found in the same naturally-occurring human antibody.
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公开(公告)号：US20240384439A1
公开(公告)日：2024-11-21
申请号：US18592484
申请日：2024-02-29
Applicant: RULES-BASED MEDICINE INC.
Inventor： Andrew Raymon Morton BRADBURY , Michael Frank ERASMUS , Andre TEIXEIRA
Abstract: Antibody libraries comprising a plurality of heavy chain variable domains and/or a plurality of light chain variable domains, which comprise complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or more features of such members. Further, the antibody libraries comprise members having heavy chain and/or light chain CDRs not found in the same naturally-occurring human antibody.
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公开(公告)号：US20240240360A1
公开(公告)日：2024-07-18
申请号：US18592456
申请日：2024-02-29
Applicant: RULES-BASED MEDICINE INC.
Inventor： Andrew Raymon Morton BRADBURY , Michael Frank ERASMUS , Andre TEIXEIRA
CPC classification number: C40B40/10 , C12N15/1037 , C12N15/81 , C40B40/08 , C40B50/06
Abstract: Antibody libraries comprising a plurality of heavy chain variable domains and/or a plurality of light chain variable domains, which comprise complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or more features of such members. Further, the antibody libraries comprise members having heavy chain and/or light chain CDRs not found in the same naturally-occurring human antibody.
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