公开(公告)号：US20170333599A1

公开(公告)日：2017-11-23

申请号：US15599152

申请日：2017-05-18

申请人： RTI Surgical, Inc.

发明人： Amanda B. LoGuidice ,  Alison P. Houlihan

IPC分类号： A61L27/46 ,  A61L27/44 ,  A61L27/58 ,  D01D5/00 ,  A61L27/18 ,  A61L27/38 ,  A61L27/54

CPC分类号： A61L27/46 ,  A61L27/18 ,  A61L27/26 ,  A61L27/32 ,  A61L27/3821 ,  A61L27/3834 ,  A61L27/3847 ,  A61L27/446 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/106 ,  A61L2300/112 ,  A61L2300/412 ,  A61L2400/12 ,  A61L2430/02 ,  D01D5/0007 ,  C08L33/08 ,  C08L67/04 ,  C08L71/02

摘要： The present application is directed to the field of scaffolds for tissue engineering. The scaffolds are typically comprised of nanofibers and are optionally biomineralized. The present application provides a process for forming nanofibrous materials via electrospinning and for biomineralizing such materials. The scaffolds of the present application can be biomineralized and contain a plurality of cells either on or within the scaffold, resulting in synthetic, bioresorbable scaffolds that can be used in various biomedical applications, such as for bone regeneration.