公开(公告)号：US20230041197A1

公开(公告)日：2023-02-09

申请号：US17253799

申请日：2019-06-19

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Sharat Singh ,  Christopher Loren Wahl ,  Harry Stylli ,  Kevin David Howe ,  Arana Perera

IPC分类号： A61M31/00 ,  A61K38/19

摘要： This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immunomodulator.

公开(公告)号：US11363964B2

公开(公告)日：2022-06-21

申请号：US15940407

申请日：2018-03-29

申请人： Progenity Inc.

发明人： Mitchell Lawrence Jones ,  Yi Liu ,  Kate LeeAnn Bechtel ,  Christopher Loren Wahl

IPC分类号： A61B5/06 ,  A61B5/00 ,  A61B5/07 ,  G16H40/67 ,  A61B5/11 ,  A61B10/00

摘要： Ingestible devices are disclosed that provide very high localization accuracy for the devices when present in the GI tract of a body. Related systems and methods are also disclosed.

公开(公告)号：US20220135666A1

公开(公告)日：2022-05-05

申请号：US16769983

申请日：2018-12-13

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Sharat Singh ,  Christopher Loren Wahl ,  Harry Stylli ,  Kevin David Howe ,  Aruna Perera

IPC分类号： C07K16/24 ,  A61K31/4196 ,  A61K31/4245 ,  A61K31/428 ,  A61K31/436 ,  A61K31/519 ,  A61K31/606 ,  A61K38/08 ,  A61K38/13 ,  A61K9/48 ,  C07K16/28 ,  A61K9/19 ,  A61K31/573

摘要： This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a S1P modulator.

公开(公告)号：US11241562B2

公开(公告)日：2022-02-08

申请号：US16299537

申请日：2019-03-12

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Russell B. Ford ,  Edward G. Solomon ,  Jeffrey A. Shimizu

IPC分类号： A61M31/00 ,  A61B10/00 ,  A61B10/02 ,  A61B5/00 ,  A61K9/00 ,  A61B1/04 ,  A61B10/04

摘要： Ingestible devices with a relatively large payload volume or sample volume, as well as related components, systems and methods, are disclosed.

公开(公告)号：US20210138213A1

公开(公告)日：2021-05-13

申请号：US16496791

申请日：2018-03-30

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Sharat Singh ,  Christopher Loren Wahl ,  Harry Stylli

IPC分类号： A61M31/00 ,  A61K9/00 ,  A61P1/04 ,  C07K16/24 ,  A61K31/436 ,  A61K9/48 ,  C07K16/28 ,  A61K38/13 ,  C12N15/113

摘要： This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immune modulatory agent (e.g., a CD40/CD40L inhibitor).

公开(公告)号：US20200245897A1

公开(公告)日：2020-08-06

申请号：US16839107

申请日：2020-04-03

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Christopher Loren Wahl ,  Gene Alan Wey ,  Aaron Olafur Laurence Philippsen ,  Mark Sasha Drlik ,  Iman Niknia

IPC分类号： A61B5/07 ,  A61B1/04 ,  A61M31/00

摘要： Ingestible devices capable of delivering a dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are disclosed. A removably attachable storage reservoir configured to be used with an ingestible device and capable of storing dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are also disclosed.

公开(公告)号：US20200221954A1

公开(公告)日：2020-07-16

申请号：US16827807

申请日：2020-03-24

申请人： Progenity, Inc.

发明人： Sharat Singh ,  Mitchell Lawrence Jones ,  Christopher Loren Wahl

IPC分类号： A61B5/00 ,  A61B10/00 ,  A61K45/06 ,  A61K49/00 ,  C12M1/00 ,  C12N1/20 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  G01N1/10 ,  G01N1/20 ,  G01N1/38 ,  G01N21/76 ,  G01N33/487 ,  G01N33/483 ,  G01N33/58 ,  A61B5/07

摘要： The present disclosure relates to gastrointestinal (GI) tract detection methods, devices and systems.

公开(公告)号：US10588608B2

公开(公告)日：2020-03-17

申请号：US15680430

申请日：2017-08-18

申请人： Progenity Inc.

发明人： Mitchell Lawrence Jones ,  Christopher Loren Wahl ,  Aaron Olafur Laurence Philippsen ,  Nicholas David Allan ,  Mark Sasha Drlik ,  Ryan Paul McGuinness ,  Sharat Singh ,  Robert S. Magyar

IPC分类号： A61B5/00 ,  A61B10/00 ,  B01L3/00 ,  G01N1/40 ,  G01N33/569 ,  A61B5/145 ,  A61B10/02

摘要： Sampling systems that include an absorbent material a preservative, such as an analyte preservative, as well as related materials and methods, are disclosed.

公开(公告)号：US20190083073A1

公开(公告)日：2019-03-21

申请号：US16194563

申请日：2018-11-19

申请人： Progenity, Inc.

发明人： Yaw Amoako-Tuffour ,  Mitchell Lawrence Jones ,  Satya Prakash

IPC分类号： A61B10/04

摘要： Various embodiments are described herein for a device and method for an ingestible medical device with a rotatable element. In some described embodiments, the ingestible medical device includes a storage sub-unit with multiple chambers each having an opening for collecting or dispensing substances from the GI tract. The device further comprises a chamber enclosure with an access port. One of the chamber enclosure and the storage sub-unit are rotatable to allow for aligning the access port with a chamber opening. The ingestible medical device includes a sensor for positioning the access port of the chamber enclosure or the storage sub-unit as one of these elements rotates.

公开(公告)号：US20180206769A1

公开(公告)日：2018-07-26

申请号：US15835303

申请日：2017-12-07

申请人： Progenity Inc.

发明人： Brian Pak ,  John Mitchell McLean ,  Paul Timothy Smith ,  Mitchell Lawrence Jones ,  Christopher Loren Wahl

IPC分类号： A61B5/1455 ,  A61B5/145 ,  A61B5/00 ,  G01N33/483 ,  G01N33/487

摘要： The present disclosure relates to gastrointestinal (GI) tract detection methods, devices and systems.